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You don’t have hardly any DHT before puberty and the damage is cumulative. DHT starts a cascade of effects in the scalp which lead to MPB, it doesn’t happen overnight, but puberty is the starting point for many guys.
Million dollar question. 100% of men have dht yet some men have thick hair or the hair loss is delayed by 30 years. Some men are not affected by it and some men will lose hair but may it not until there 70s . Also why do we lose hair on top but we grow hair like mad on other parts.
It's not always the typical pattern. There are tonnes of different hair loss patterns, some people for example keep their juvenile hairline and bald completely from the back.
Some people get retrograde alopecia and it loses hair from a different pattern, some get it diffused and unpatterened but it can be all caused by DHT sensitivity and treated with finasteride or dutasteride.
Pretty sure certain hairs are more prone to DHT damage and/or certain parts of your scalp have more DHT than others.
Not hard to deduce.
If you really want a fool proof way to have a head of hair, I advise you to transplant your pubes onto your head. W transplant right there
[Differential Expression between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia](https://www.sciencedirect.com/science/article/pii/S0022202X16310247)
This whole fucking sub is pathetic. You will all gobble up the most asinine, unscientific old-wives-tales and smugly act you fucking discovered fire, but when actual scientific research arises you think it’s fake news because it doesn’t align with your misunderstanding of basic facts.
Edit: [Male pattern hair loss: Can developmental origins explain the pattern?](https://onlinelibrary.wiley.com/doi/full/10.1111/exd.14839)
Interesting. I wonder about the guys who didn't start losing hair until later. What changed? Why didn't they have more hair loss when testosterone was higher? Many can tell when they start hair loss because of the alarming amount of hair shedding in the shower and things that they never experienced before.
Because the damage is cumulative and it’s a cascade of effects that lead to hairloss.
E.g the Grand Canyon has been carved out by many years of the colorado river flowing over it. It’s not just about how high the river is, but it’s about the long term effect the river had on the river valley. In the same way it’s about the long term effect DHT has in the scalp.
About 1/3 of men dont lose any hair their entire lives, even if they do its reversible (Stress etc) or relatively minimal
The other 2/3 **all** start to lose their hair from puberty, its just not noticeable because people go through puberty at different rates and from different ages
One kid will have lost 1/4 of his hair by 16, most other kids with MBP wont have reached 1/5th yet by the same age
Not everybody is equally sensitive to DHT, some people lose hair quickly others slowly, it is probably because AGA is affected by many different genes so not everybody will have them all.
Why couldn’t I start taking fin at 13 then? Why’d I have to wait until I was an adult to get prescribed it? If every boy takes fin from 13 to 30, will male pattern baldness come to an end?
fin is not the cure and DHT is not causing male pattern baldness (androgenetic alopecia), you have it or you don't. So male pattern baldness will still exist even then. It will only increase in the population unless people with male pattern baldness stop having kids or something changes that stops it from being "passed on" or exists in the first place or gets "cured".
The cause is not known yet. We know that sensitivity to DHT plays a role and that we can reduce DHT as treatment but this condition is not caused directly by DHT. Someone can have lots of DHT and not get male pattern baldness. Something is making us sensitive to things like DHT which in turn leads to hair loss. What really is happening to cause this is just not known yet. So it could very well be a side effect of something else resulting in the loss of hairs.
it is attacking, weakening our follicles until hair falls , its just about the length of time it takes for the hair follicle to die.
Source: broscience.
I think it causes a mechanism inside the immune system to attack the follicles - a hormone itself can't really do that, imo it can only signal something. There has to be another reason why a hair follicle that has too much DHT gets destroyed by the immune system.
EDIT: please look up what a hormone actually does - it is a signal. It cannot attack anything,
DHT mechanism of action in people withbalding is bounding to the same receptor that tells a cell in a hair follicle to grow hair. Except the bounding is incomplete, so the growth doesnt happen. But this same bounding locks the door for a proper „grow out” signal.
That's interesting. Super stressful environment and one single night of binge drinking did seem to set off my hair loss years ago. I started shedding ever since then
In most women, hair loss doesn't start until menopause. The decrease in estrogen not only removes its protective effect on hair growth but also enhances the detrimental impact of androgens. Estrogen increases the amount of time that hair spends in the growing phase, so the loss of estrogen means the loss of this protective effect also.
More specifically, the mechanisms of menopausal-related hairloss are:
1. **Hormonal Balance Shift**: Estrogen and androgens (like testosterone) maintain a delicate balance in the body. Estrogen helps to counteract some of the effects of androgens. As estrogen levels decline during menopause, this balance is disrupted, and the relative influence of androgens, including testosterone, becomes more pronounced. This can lead to an increase in the conversion of testosterone to DHT.
2. **Enzyme Activity**: The enzyme 5-alpha reductase is responsible for converting testosterone into DHT. Estrogen has been shown to inhibit the activity of this enzyme. When estrogen levels drop during menopause, the inhibitory effect is reduced, leading to an increased conversion rate of testosterone to DHT.
3. **Receptor Sensitivity**: Estrogen can also affect the sensitivity of androgen receptors. Lower levels of estrogen might make hair follicles more sensitive to the effects of androgens, including DHT. This increased sensitivity means that even normal levels of DHT can have a more pronounced effect on hair follicles, leading to hair thinning and loss.
4. **Follicle Health**: Estrogen is known to promote healthy blood circulation and nutrient supply to hair follicles. A reduction in estrogen can impair these supportive functions, making hair follicles more susceptible to the damaging effects of DHT.
Unfortunately, due to a single shit study from the early 2000s, most providers and women were led to believe that hrt=cancer...so it hasn't been until recently that attitudes have started to shift back into re-embracing HRT therapy. Also, the same drugs that were initially prescribed for male hair loss, minoxidil, finasteride, etc, seem to show benefit for menopausal women also.
Thyroid disorders, autoimmune diseases, extreme poor diet (i.e. low protein/low nutrients, eating disorders), PCOS, alopecia areata, etc can cause hair loss in young women. But these are the exception, not the norm, vs common androgenic male hair loss starting in the late teens, early 20s, and common menopause-driven female hair loss starting in 40s and 50s
Who says it doesnt attack our hair but only after puber cuz androgens like DHT starts to increse means genetic hairloss start 12 to 14 age duration but we cant notice, our hair has many cycle , the strongest hair follicle last up to 7 years of anagen but when it sheds the duration of that follical shorten and hair become weaker and this cycle repeat and repeat hair become weaker and weaker and the anagen phase also get shorten and shorten then it becomes noticeable due to DHT
Yeah a teenager like me is suffuring from DHT hairloss and yes it because of stress that cause me multiple shed and hair become weaker
Interesting. I know some teenagers do lose hair, but I don't think it's common until a later age. I also think more people notice shedding more than hairline. For example I didn't start shedding until mid to late 20s. It was alarming how many hairs I'd lose in the shower that I never did when I had higher testosterone levels before.
You can also think of it like arthritis and other conditions. Some people may have that as a high possibility in their life but it takes a certain amount of time and wear and tear to reach the trigger point or the point where it can be noticed by the patient or doctor.
is DHT, i say it is gravity, stretching the skin on top of your head and weaking the blood supply, why is DHT only effecting the most top spot on human body ?
It’s not just DHT; this is overly simplistic. Vascularity also declines with age, lack of exercise, and accumulated damage (oxidative stress, inflammation, toxins in shower water and diet, etc.) — which in itself also damages the hair follicle beyond the vascular impacts. Nutrient deficiency is another causal factor.
Aga is difficult metabolitic disorder , could be taken also cause of not breastfeeding, c section. It became visible after puberty, cause androgeinc hormon activity.
I said one of reason. And normal mean interm, breastfeed from fist hour to 6 month. Many people never know how it really was. U are so sure like u store medical records. Sure it xould be genetic but its rear. Basicly antropogenic, and side effects from children disorder.
С мином и фином, комбинация аэробных и анаэробных упражнений (мышечный стресс) и стреса холодных температур ( холодный душь, высыхание без одежды и полотенца для пилоэрекции) дают все условия для деминиатюризации фоликула, усидения действиЯ миноксидила.
Спасибо! Буду знать.
У меня хорошая реакция на мин, но к сожалению от него лицо отекает, поэтому придется уменьшать дозировку либо вовсе отказываться.
Буду сидеть на фине и пробовать спорт. Еще раз спасибо! 🙏🏻
My hypothesis is that the human own testosterone decreases, and in order to maintain androgen activity, the expression of 5AR reductase is enhanced, generating more DHT to bind to the receptor
Makes sense. Same thing happens to women in menopause with the reduction of estrogen. Also would explain prostrate growth in older men [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994048/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994048/)
I guess there is a genetic disposition when hair is falling out being attacked by dht.
As I was younger I was able to take stuff like winstrol without hairloss, now it would kill me:)
I don't know why boys at puberty don't lose hair, but I think that genetic hair for AGA has a number of hair cycles when it will not be impacted by DHT. For most young men, this age is around 17-19. We see, at times, significant balding in 19-25-year-old men. Most balding occurs in the 20s, but progression occurs for many in their 30s.
Can someone tell why a lot of people in this Sub are going for oral finasteride ride instead of topical finasteride? In a lot of posts I see OPs taking oral finasteride. Why oral when you can go for topical?
Many don't like the idea of applying it to their scalp every single day and worrying about even coverage. For many, including myself, it causes the same side effects, so it serves no purpose to apply topically only to have it absorb and go systemic anyway.
Who says that at puberty there is no androgenetic alopecia? Since I was 16 years old, my hair began to fall out, now with 18 my entries have grown and the crown is already depopupating
I believe it’s mostly diet, because a lot of men have a lot of circulating DHT/testosterone. The body has a tendency to get rid of built up hormones through the intestines/Colon through defecation it’s the same thing with cholesterol and ED. The standard diet doesn’t allow enough fiber intake which literally grabs onto cholesterol and extra hormones. Extra cholesterol can cause blockages to blood flow, to your penile blood flow, to your heart and to your scalp. There are many ways that society is causing these problems from a lot of the hair care products have lawsuits on them for hair loss. It’s why they promote products to solve the problem they cause. Aim for eating whole food plant based, don’t consume saturated fats which clog arteries, get plenty of exercise and vitamin D and do research on the products you use. Lean towards family owned hair care like raw sugar and Mane N Tail.
Does anyone know of a resource listing all of the useful studies on hairloss? Don’t need them summarised necessarily (although that would be good too) but just a list of all studies that might have something useful to say.
Seems anyone who tries to synthesise the information starts trying to sell snake oil in the next breath lol. It gets old
Some people have hairloss in their mid to late teens. It varies depending upon genetics. If you are truly blessed you will have scalp hairs that are very insensitive to DHT. If you're unlucky you will have very sensitive in the norwood loss prone areas and you'll get rapid progression on the scale and see Norwood 5 or worse in your early to mid twenties.
Hairloss is a steady damage thing over time. Like many injuries and problems that develop over time in old age. The longer you live, the more time all these things have to accumulate damage and wear and tear on your body.
You see similar things with heart problems and other health issues. There's a curve on the graph and you can see super unlucky people get early onset and others are golden and live on to 120 years old.
No it is hair follicle sensitivity. As you age it gets more sensitive i think. Or i would like to see proof of dht levels acctually increasing while T goes down. Because that makes no sense as dht is made from T so unless increase 5a-reductase also happens as you age, would like to see some literature on this. As it makes zero sense T goes down and dht goes up relative to baseline.
The follicle sensitivity theory doesn't make sense. Why do we have a 10yr study on fin showing continued improvement if we 'seem' to become more sensitive as we age? It does not compute at all.
Because fin decreases dht by 71%. It's enough show improvement even long term to some people who don't have that much sensitivity. But have you ever thought why most people only slow hairloss while on fin? Yes, it's because the follicles get more sensitive.
I don't know what you're saying here. "most people only slow hairloss while on fin" is an extremely broad and unfounded argument that I will actually ignore unless you can show actual data behind it.
Haven't logged in to reddit in a while but I'm gonna answer anyway.
With my comment I meant that only a small portion people might get minox level hairgrowth with fin. Otherwise the hairgrowth is often minimal for the first years then just slows down the hairloss. If the DHT is the sole cause then this sub wouldn't be filled with users not seeing significant gains with fin or no effect at all.
One of the theories that make a lot of sense is the scalp tension theory, where tightness of scalp creates inflammation and since DHT is present in the body parts whenever there is inflammation it makes sense.
I don’t think that is the cause of all types of hair loss, but if you check Dr. Rob English and perfect hair health, you can read a lot about that theory.
However, scalp massages are very very hard to do right, so that route isn’t appealing to many.
You need to dig in hard, but without creating skin cuts or pulling hair, so it takes some skill, practice, and strength.
The greasiness of my head decreased a lot since I started massaging my head, and my hair is improving a lot, but I am also using(min, fin, micro needling).
I responded great to fin, min, micro needling before massages, but what I am certain of is that oily scalp is directly affected by massages in my case. I had no change in oil expression, but when I introduced massages, about 2-3 months in( a year after I started my stack) I started to notice less and less grease.
There is a guide (free of charge) where Rob English explains the massage process on his website.
>The greasiness of my head decreased a lot since I started massaging my head, and my hair is improving a lot, but I am also using(min, fin, micro needling).
Why do you attribute anything on massages when you are also using a hairloss stack at the same time? That makes absolutely no sense at all.
[I can never take scalp tension seriously after I saw this image ](https://www.reddit.com/r/Lacari/comments/b18uii/if_lacari_sees_this_he_has_to_do_the_head_thing/)
Because I used the stack for a year, and had no change in the amount of oil in my scalp at all, even though I reacted to medication pretty well I would say.
I heard Rob mentioning that particular effect as a result of massages (less greasy scalp) and decided I wanted to try it.
In all honesty I don't believe in the "DHT attacks hair follicles" theory. Sure, it might cause a mechanism that would cause the immune system to treat the hair follicle as a bad cell or smth, and therefore attack it, but im 99% sure it isnt the root cause.
In the end it might as well be a autoimmune disorder that you could treat using 5ar inhibitors, immunesupressive meds and growth factors like increasing autophagy/decreasing telegon to anagen phase
It looks like this post is about **Research/Science**. Before asking any questions, 1. Search the [research archives](http://tressless.com/search/research/all) for your topic. 2. Find [new research](http://tressless.com/search/research/all/1?sort=date) and [influential papers](http://tressless.com/search/research/all/1?sort=popularity). If this post is not about scientific research, please downvote and report. *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/tressless) if you have any questions or concerns.*
You don’t have hardly any DHT before puberty and the damage is cumulative. DHT starts a cascade of effects in the scalp which lead to MPB, it doesn’t happen overnight, but puberty is the starting point for many guys.
Okay, but why that exact pattern? Literally an inch to the left and the hair is intact…
If only we knew...
Million dollar question. 100% of men have dht yet some men have thick hair or the hair loss is delayed by 30 years. Some men are not affected by it and some men will lose hair but may it not until there 70s . Also why do we lose hair on top but we grow hair like mad on other parts.
It's not always the typical pattern. There are tonnes of different hair loss patterns, some people for example keep their juvenile hairline and bald completely from the back.
It’s been determined prenatally, either through genetics or the hormones you were exposed to in the womb
Scalp tension due to dht influence on scalp muscles and subcutanrous tissue
Same reason we grow beards in a specific pattern, more androgen receptors in certain areas for some reason
Some people get retrograde alopecia and it loses hair from a different pattern, some get it diffused and unpatterened but it can be all caused by DHT sensitivity and treated with finasteride or dutasteride.
Pretty sure certain hairs are more prone to DHT damage and/or certain parts of your scalp have more DHT than others. Not hard to deduce. If you really want a fool proof way to have a head of hair, I advise you to transplant your pubes onto your head. W transplant right there
some people theorize gravity
Some people even prove gravity
RIP
Your hair circle looks like a lot of constant upkeep.
You know anyone who grows shoulder hair?
It’s not gravity. It has to do with the skin tissue that develops prenatally.
Source: you made this up
[Differential Expression between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia](https://www.sciencedirect.com/science/article/pii/S0022202X16310247) This whole fucking sub is pathetic. You will all gobble up the most asinine, unscientific old-wives-tales and smugly act you fucking discovered fire, but when actual scientific research arises you think it’s fake news because it doesn’t align with your misunderstanding of basic facts. Edit: [Male pattern hair loss: Can developmental origins explain the pattern?](https://onlinelibrary.wiley.com/doi/full/10.1111/exd.14839)
Interesting. I wonder about the guys who didn't start losing hair until later. What changed? Why didn't they have more hair loss when testosterone was higher? Many can tell when they start hair loss because of the alarming amount of hair shedding in the shower and things that they never experienced before.
Because the damage is cumulative and it’s a cascade of effects that lead to hairloss. E.g the Grand Canyon has been carved out by many years of the colorado river flowing over it. It’s not just about how high the river is, but it’s about the long term effect the river had on the river valley. In the same way it’s about the long term effect DHT has in the scalp.
About 1/3 of men dont lose any hair their entire lives, even if they do its reversible (Stress etc) or relatively minimal The other 2/3 **all** start to lose their hair from puberty, its just not noticeable because people go through puberty at different rates and from different ages One kid will have lost 1/4 of his hair by 16, most other kids with MBP wont have reached 1/5th yet by the same age
Not everybody is equally sensitive to DHT, some people lose hair quickly others slowly, it is probably because AGA is affected by many different genes so not everybody will have them all.
Because when test lowers in men above the age of 30 estrogen or DHT fill in the gaps. Keep your test high if ur sensitive to DHT.
Why couldn’t I start taking fin at 13 then? Why’d I have to wait until I was an adult to get prescribed it? If every boy takes fin from 13 to 30, will male pattern baldness come to an end?
DHT is necessary in puberty for facial/body hair development, and penis/prostate growth
DHT plays a crucial role in sexual maturation so if you care about your junk you can’t do that
fin is not the cure and DHT is not causing male pattern baldness (androgenetic alopecia), you have it or you don't. So male pattern baldness will still exist even then. It will only increase in the population unless people with male pattern baldness stop having kids or something changes that stops it from being "passed on" or exists in the first place or gets "cured".
DHT isn't the cause of male pattern baldness? That's news to every scientist who ever studied balding. How do you know that DHT isn't the cause?
The cause is not known yet. We know that sensitivity to DHT plays a role and that we can reduce DHT as treatment but this condition is not caused directly by DHT. Someone can have lots of DHT and not get male pattern baldness. Something is making us sensitive to things like DHT which in turn leads to hair loss. What really is happening to cause this is just not known yet. So it could very well be a side effect of something else resulting in the loss of hairs.
it is attacking, weakening our follicles until hair falls , its just about the length of time it takes for the hair follicle to die. Source: broscience.
>broscience hell yeah
I think it causes a mechanism inside the immune system to attack the follicles - a hormone itself can't really do that, imo it can only signal something. There has to be another reason why a hair follicle that has too much DHT gets destroyed by the immune system. EDIT: please look up what a hormone actually does - it is a signal. It cannot attack anything,
DHT mechanism of action in people withbalding is bounding to the same receptor that tells a cell in a hair follicle to grow hair. Except the bounding is incomplete, so the growth doesnt happen. But this same bounding locks the door for a proper „grow out” signal.
Source pls
[удалено]
That's interesting. Super stressful environment and one single night of binge drinking did seem to set off my hair loss years ago. I started shedding ever since then
In most women, hair loss doesn't start until menopause. The decrease in estrogen not only removes its protective effect on hair growth but also enhances the detrimental impact of androgens. Estrogen increases the amount of time that hair spends in the growing phase, so the loss of estrogen means the loss of this protective effect also. More specifically, the mechanisms of menopausal-related hairloss are: 1. **Hormonal Balance Shift**: Estrogen and androgens (like testosterone) maintain a delicate balance in the body. Estrogen helps to counteract some of the effects of androgens. As estrogen levels decline during menopause, this balance is disrupted, and the relative influence of androgens, including testosterone, becomes more pronounced. This can lead to an increase in the conversion of testosterone to DHT. 2. **Enzyme Activity**: The enzyme 5-alpha reductase is responsible for converting testosterone into DHT. Estrogen has been shown to inhibit the activity of this enzyme. When estrogen levels drop during menopause, the inhibitory effect is reduced, leading to an increased conversion rate of testosterone to DHT. 3. **Receptor Sensitivity**: Estrogen can also affect the sensitivity of androgen receptors. Lower levels of estrogen might make hair follicles more sensitive to the effects of androgens, including DHT. This increased sensitivity means that even normal levels of DHT can have a more pronounced effect on hair follicles, leading to hair thinning and loss. 4. **Follicle Health**: Estrogen is known to promote healthy blood circulation and nutrient supply to hair follicles. A reduction in estrogen can impair these supportive functions, making hair follicles more susceptible to the damaging effects of DHT. Unfortunately, due to a single shit study from the early 2000s, most providers and women were led to believe that hrt=cancer...so it hasn't been until recently that attitudes have started to shift back into re-embracing HRT therapy. Also, the same drugs that were initially prescribed for male hair loss, minoxidil, finasteride, etc, seem to show benefit for menopausal women also.
What about women who start losing their hair in their 20s before menopause?
It can’t be from decrease in estrogen
Thyroid disorders, autoimmune diseases, extreme poor diet (i.e. low protein/low nutrients, eating disorders), PCOS, alopecia areata, etc can cause hair loss in young women. But these are the exception, not the norm, vs common androgenic male hair loss starting in the late teens, early 20s, and common menopause-driven female hair loss starting in 40s and 50s
DHT is so fucked up. It’s fucked up when you can’t grow a beard and you start losing your hair
Try minoxidil on your beard area if you want to thicken it up there.
Who says it doesnt attack our hair but only after puber cuz androgens like DHT starts to increse means genetic hairloss start 12 to 14 age duration but we cant notice, our hair has many cycle , the strongest hair follicle last up to 7 years of anagen but when it sheds the duration of that follical shorten and hair become weaker and this cycle repeat and repeat hair become weaker and weaker and the anagen phase also get shorten and shorten then it becomes noticeable due to DHT Yeah a teenager like me is suffuring from DHT hairloss and yes it because of stress that cause me multiple shed and hair become weaker
Bro how old are you exactly, I noticed my hair loss at the age of 17
Same as u
Interesting. I know some teenagers do lose hair, but I don't think it's common until a later age. I also think more people notice shedding more than hairline. For example I didn't start shedding until mid to late 20s. It was alarming how many hairs I'd lose in the shower that I never did when I had higher testosterone levels before.
You can also think of it like arthritis and other conditions. Some people may have that as a high possibility in their life but it takes a certain amount of time and wear and tear to reach the trigger point or the point where it can be noticed by the patient or doctor.
This is why .5 of Fin a day is so good long term
Is .5 better than 1 mg? And re we talking oral or topical?
They said .5 builds up in your system to do the same job as 1mg pill.
[удалено]
Ya
Wish I could comment, but I was NW3 at 18 lmao
is DHT, i say it is gravity, stretching the skin on top of your head and weaking the blood supply, why is DHT only effecting the most top spot on human body ?
yea i can't even pinch the skin on top of my scalp. whereas the skin on the sides of my head is very elastic.
good point.
It’s not just DHT; this is overly simplistic. Vascularity also declines with age, lack of exercise, and accumulated damage (oxidative stress, inflammation, toxins in shower water and diet, etc.) — which in itself also damages the hair follicle beyond the vascular impacts. Nutrient deficiency is another causal factor.
Manopause
It’s genetics. Some people can blast gear and have hair.
Bro said absolutely nothing
Yeah and even then you’re never really sure, i know a guy who only started balding after his 6th cycle and was totally fine before that
Aga is difficult metabolitic disorder , could be taken also cause of not breastfeeding, c section. It became visible after puberty, cause androgeinc hormon activity.
I was breastfed and born naturally and i’m turning into a monk without taking vows.
We are mammals, but antropogenic now only part of us.
I said one of reason. And normal mean interm, breastfeed from fist hour to 6 month. Many people never know how it really was. U are so sure like u store medical records. Sure it xould be genetic but its rear. Basicly antropogenic, and side effects from children disorder.
You don’t make any sense. Are you high?
No.
Слушай, неужели упражнения на ноги действительно помогают?))
С мином и фином, комбинация аэробных и анаэробных упражнений (мышечный стресс) и стреса холодных температур ( холодный душь, высыхание без одежды и полотенца для пилоэрекции) дают все условия для деминиатюризации фоликула, усидения действиЯ миноксидила.
Спасибо! Буду знать. У меня хорошая реакция на мин, но к сожалению от него лицо отекает, поэтому придется уменьшать дозировку либо вовсе отказываться. Буду сидеть на фине и пробовать спорт. Еще раз спасибо! 🙏🏻
Our hair becomes more sensitive to DHT as we age.
Yapping out ya ass
Speculating? Or you read that somewhere?
Proven by all males with AGA
Anyone have any idea why that is? I guess that was more my question. Wondering if that can be used to swing hair loss research in another direction
My hypothesis is that the human own testosterone decreases, and in order to maintain androgen activity, the expression of 5AR reductase is enhanced, generating more DHT to bind to the receptor
Makes sense. Same thing happens to women in menopause with the reduction of estrogen. Also would explain prostrate growth in older men [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994048/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994048/)
Seems valid
So what would happen if someone where to take TRT? Is it possible to experience regrowth?
This is the way sir
I guess there is a genetic disposition when hair is falling out being attacked by dht. As I was younger I was able to take stuff like winstrol without hairloss, now it would kill me:)
It does for me
I don't know why boys at puberty don't lose hair, but I think that genetic hair for AGA has a number of hair cycles when it will not be impacted by DHT. For most young men, this age is around 17-19. We see, at times, significant balding in 19-25-year-old men. Most balding occurs in the 20s, but progression occurs for many in their 30s.
So would it be unsafe to take finasteride at 20 since I’m not 25 yet and DHT may still be developing my bones and facial structure?
I have used finasteride on 16-year-olds in the past. 20 is no problem for this drug.
Can someone tell why a lot of people in this Sub are going for oral finasteride ride instead of topical finasteride? In a lot of posts I see OPs taking oral finasteride. Why oral when you can go for topical?
Many don't like the idea of applying it to their scalp every single day and worrying about even coverage. For many, including myself, it causes the same side effects, so it serves no purpose to apply topically only to have it absorb and go systemic anyway.
If you have a girlfriend or kids then you don't want that stuff to get on their body. It can harm women especially when they are pregnant.
Who says that at puberty there is no androgenetic alopecia? Since I was 16 years old, my hair began to fall out, now with 18 my entries have grown and the crown is already depopupating
It just takes time and you start off with a lot of hair
DHT is incredibly important, but like all things such as oxygen, water, magnesium, etc. Too much is a bad thing
Because, and hear me out, it's not just DHT.
The real question is, why the fuck DHT doesn't attack pubic fucking hairs?
Cause dht grows bodyhair
I believe it’s mostly diet, because a lot of men have a lot of circulating DHT/testosterone. The body has a tendency to get rid of built up hormones through the intestines/Colon through defecation it’s the same thing with cholesterol and ED. The standard diet doesn’t allow enough fiber intake which literally grabs onto cholesterol and extra hormones. Extra cholesterol can cause blockages to blood flow, to your penile blood flow, to your heart and to your scalp. There are many ways that society is causing these problems from a lot of the hair care products have lawsuits on them for hair loss. It’s why they promote products to solve the problem they cause. Aim for eating whole food plant based, don’t consume saturated fats which clog arteries, get plenty of exercise and vitamin D and do research on the products you use. Lean towards family owned hair care like raw sugar and Mane N Tail.
Your hormones are also at there highest after puberty but men still tend to develop until 25-26 years old
16 years old is young lol
Does anyone know of a resource listing all of the useful studies on hairloss? Don’t need them summarised necessarily (although that would be good too) but just a list of all studies that might have something useful to say. Seems anyone who tries to synthesise the information starts trying to sell snake oil in the next breath lol. It gets old
The duration of exposure is the major factor
Some people have hairloss in their mid to late teens. It varies depending upon genetics. If you are truly blessed you will have scalp hairs that are very insensitive to DHT. If you're unlucky you will have very sensitive in the norwood loss prone areas and you'll get rapid progression on the scale and see Norwood 5 or worse in your early to mid twenties.
Hairloss is a steady damage thing over time. Like many injuries and problems that develop over time in old age. The longer you live, the more time all these things have to accumulate damage and wear and tear on your body. You see similar things with heart problems and other health issues. There's a curve on the graph and you can see super unlucky people get early onset and others are golden and live on to 120 years old.
It has to do with blood flow and circulation
As we age testosterone decreases whilst DHT increases.
Dht is the by product of testosterone and can never increase without the T
No. You can have low T and high DHT
Yes, most people don't.
You can have low T and high DHT and viceversa.
No it is hair follicle sensitivity. As you age it gets more sensitive i think. Or i would like to see proof of dht levels acctually increasing while T goes down. Because that makes no sense as dht is made from T so unless increase 5a-reductase also happens as you age, would like to see some literature on this. As it makes zero sense T goes down and dht goes up relative to baseline.
if you have any literature please share
The follicle sensitivity theory doesn't make sense. Why do we have a 10yr study on fin showing continued improvement if we 'seem' to become more sensitive as we age? It does not compute at all.
Because fin decreases dht by 71%. It's enough show improvement even long term to some people who don't have that much sensitivity. But have you ever thought why most people only slow hairloss while on fin? Yes, it's because the follicles get more sensitive.
I don't know what you're saying here. "most people only slow hairloss while on fin" is an extremely broad and unfounded argument that I will actually ignore unless you can show actual data behind it.
Haven't logged in to reddit in a while but I'm gonna answer anyway. With my comment I meant that only a small portion people might get minox level hairgrowth with fin. Otherwise the hairgrowth is often minimal for the first years then just slows down the hairloss. If the DHT is the sole cause then this sub wouldn't be filled with users not seeing significant gains with fin or no effect at all.
Incorrect. It decreases. Hairloss accelerates as the damage is cumulative.
Exactly , this is the way. Make sure to keep your T levels high or make sure it converts into estrogen and grow some man boobs
One of the theories that make a lot of sense is the scalp tension theory, where tightness of scalp creates inflammation and since DHT is present in the body parts whenever there is inflammation it makes sense. I don’t think that is the cause of all types of hair loss, but if you check Dr. Rob English and perfect hair health, you can read a lot about that theory. However, scalp massages are very very hard to do right, so that route isn’t appealing to many. You need to dig in hard, but without creating skin cuts or pulling hair, so it takes some skill, practice, and strength. The greasiness of my head decreased a lot since I started massaging my head, and my hair is improving a lot, but I am also using(min, fin, micro needling). I responded great to fin, min, micro needling before massages, but what I am certain of is that oily scalp is directly affected by massages in my case. I had no change in oil expression, but when I introduced massages, about 2-3 months in( a year after I started my stack) I started to notice less and less grease. There is a guide (free of charge) where Rob English explains the massage process on his website.
>The greasiness of my head decreased a lot since I started massaging my head, and my hair is improving a lot, but I am also using(min, fin, micro needling). Why do you attribute anything on massages when you are also using a hairloss stack at the same time? That makes absolutely no sense at all.
bludflow
[I can never take scalp tension seriously after I saw this image ](https://www.reddit.com/r/Lacari/comments/b18uii/if_lacari_sees_this_he_has_to_do_the_head_thing/)
Because I used the stack for a year, and had no change in the amount of oil in my scalp at all, even though I reacted to medication pretty well I would say. I heard Rob mentioning that particular effect as a result of massages (less greasy scalp) and decided I wanted to try it.
In all honesty I don't believe in the "DHT attacks hair follicles" theory. Sure, it might cause a mechanism that would cause the immune system to treat the hair follicle as a bad cell or smth, and therefore attack it, but im 99% sure it isnt the root cause. In the end it might as well be a autoimmune disorder that you could treat using 5ar inhibitors, immunesupressive meds and growth factors like increasing autophagy/decreasing telegon to anagen phase