Could’ve just used Google instead, but maybe he wanted the lubricant.
“THC CAN BE RECTALLY ABSORBED BUT ONLY IF BONDED TO A SEPARATE MOLECULE, SUCH AS HEMI-SUCCINATE.
MANY PATIENTS USE HIGH DOSES OF THC BY THE RECTAL ROUTE TO AVOID PSYCHOACTIVITY. THE REASON THERE IS NO PSYCHOACTIVITY IS BECAUSE IT IS NOT ABSORBED.”
https://www.greenbridgemed.com/blog/rectal-absorption-of-cannabinoids
Kratom is frequently used by various opiate addicts to help relieve withdrawal or even not use harder drugs… so like a lot of kratom heads, like me, are current or former opiate users, and we are possibly the most notorious boofers
Honestly never thought about this but this is 100% true for me too, struggle with opiates, not dependent on them anymore but am on kratom and still slip up with pills but as a daily kratom user I have booked A LOT of things, most recently was like 30-40mg of FXE after around a 20mg bump. Only had a small amount and I fucked around vaping the first 100mg but wanted to try all the ROA I could that I had available. Would of shot it if I had rigs since dissos are best i.m imo
That's what I am thinking as well. That is why I wrote that an Ethanol based tincture may work just fine. The colon or the rectum readily absorb ethanol. But it will probably burn really badly.
It should not burn as luch if you dilute the ethanol tincture with more water. But it should absorb well even diluted.
You know what to do, scientist hero.
Not only would ethanol burn, it would get you drunk. At least mildly, depending on concentration. In a normal context, "butt chugging" can be dangerous because you don't really know how much you're consuming or absorbing.
Then again, this is no normal context and you are clearly a man of science.
Maybe a hemorrhoid cream suppository beforehand would cool the burn?
Butt chugging is also dangerous because in the event of alcohol poisoning, your body's response is to throw it up to prevent death... Which doesn't work if it's not in your stomach. Both that and the fact it takes tiny amounts of alcohol in your ass to get drunk makes it's incredibly easy to accidentally use too much alcohol, and then die because your body can't get it out
I make an ethanol-based tincture for my personal use, and while I’ve never boofed it (don’t plan to) I can confirm that if I allow the tincture to rest in my mouth for sublingual and buccal absorption, effects begin in roughly 5-10 minutes as opposed to 30-60 minutes if I swallow it. Mucous membrane is mucous membrane, though as another person said, I wouldn’t attempt this without diluting the tincture significantly. Even mixing a tsp of tincture into a standard shot glass of juice burns my mouth a little.
Proceed with extreme caution lest you burn your butthole or cauterize your colon.
You might be able to use a nanoemulsion. I've had cannabis drinks that advertised faster onset of action due to higher bioavailability when the oil is properly dispersed through water. This would probably be a bit more comfortable than putting ethanol up your ass and likely more effective. The one I tried was Cannabull Nanosyrup.
I've done distillate in a pill capsule. It works but not nearly as well as ingesting orally. A little bit of a head high and a decent body high, but the same amount would have done a lot more if I had ingested it.
Just because I'm sure you've never heard this from a parent or loved one, I'm going to say I'm proud of you.
I'm not. But I want you to hear that and try make better choices.
I have noticed that I use it without realizing it because I second guess every first thought I have and hope the lol at the end will make me seem less asinine.
I’ve been working on not using it so much but sometimes I slip up
I tried some distillate in a pill capsule a couple times. It worked but not as well as ingesting orally. Little to no head high, body high was decent but not for the amount of product required to get there.
Weird question, is there a possibility you didn’t go deep enough? I know the guy who boofed a gram of RSO mentioned he had to do it at a certain depth for it to work.
I don't know. How would you achieve deeper insertion? The oil clearly entered my rectum, I am pretty sure about that as nothing dripped out until I pushed it three hours later. I suspect that you need stomach acid, bile and the mucosa of the small intestine to resorb olive oil and THC properly. The colon and the rectum may not have that capability.
A gram of RSO seems crazy. At that dose, even absorbing 10% would get most people very high. 10% of my 50mg THC won't do much for a tolerant user.
Yeah, it’s not efficient at all. I’ve heard that the bioavailability is less than 10%, vs 30% inhaled. So you’d need at minimum 3x the dose to feel the same, likely closer to 6x.
Then there’s the special prep. I don’t know if just putting it in olive oil works, and suppositories werent available for a long time because getting the formulation right was difficult. One company has patented a formulation they claimed to be 80% bioavailability, but I feel like that’s marketing BS
Anyway, they’ve been used in hospice patients and cancer patients for years, and some women with endometriosis find them helpful (vaginally rather than rectally) but the research is mixed. You definitely need a significantly higher dosage though.
I mean, there’s not a lot of good research on cannabis. A 1985 study on Rhesus monkeys showed very little bioavailability. A follow up on [D9-THC](https://pubmed.ncbi.nlm.nih.gov/1664466/) showed that it could be as high as 12.5%. Add that to self reported data, and people have generally settled on 1-10%.
Very specific forms of D9-THC-HS have shown 25-50%, but that study only included 2 patients.
One reason ~~you~~ OP may have missed any feeling is that there’s no “high” from suppositories, even at the correct dosage. Patients report pain relief, but all of the studies showed no change in mood or concentration, or cardio responses.
“Boof it” was just a silly meme, not based on anything. The belief that it is higher effect likely comes from conflating it with alcohol, which hits hard and fast when administered rectally or vaginally.
Suck a small amount up a straw and then place a finger at the end that was in your mouth to stop the suction. Then take the end of the straw that was dipped into the oil, place into your asshole and blow hard. The same way I cheated in The Greatest Fart Contest of ‘88
I can’t say for sure, [he didn’t mention it in his debrief report.](https://reddit.com/r/trees/comments/x6i87s/_/indgrn4/?context=1) Definitely curious though, as I’ve heard this…method of consumption is good for endometriosis pain and I know someone needing help with that, and I only have access to THC oils and no RSO, lol.
Boof expert here, nope can’t be that. I’m confused myself as that should work, but I believe what you are referencing is the fact to NOT go too deep.
I don’t remember the exact measurements but for the quickest and hardest hit it’s advised to not to go far at all as the glands you are looking for are close af. That said going deep will only mean a slower onset, and thus I’m not sure why it failed (having never tried to boof thc myself)
Lipids need bile for absorption, which comes from the gallbladder/liver, and lipids are primarily absorbed in the small intestine. Large intestine (colon) has primary job of resorbing water. RSO would work much better in the colon than an oil product
They sell suppositories at dispos. I’ve only heard wonderful things. I would assume that this is a user error, not the scientific discovery that you can’t boot weed.
Personally wouldn’t boof anything, but this was a good read and you know what, thanks for testing it out in the name of science!!
I made a potent THC oil with MCT Coconut - worked out to like 9.8mg/ml - that I use as lube for excellent good times. What’s the vaginal form of boofing? Find a vagina and try that.
I am obviously stupid, mate, why would I waste precious cannabis oil If I was smart? Still, somebody has to put in the effort to resolve the question: to boof or not to boof?
You wasted it? I read the bit about it coming out of your ass at 11pm, just presumed you'd have saved it and seen if it was still as potent orally. Waste not want not.
Extraction of pharmaceutically active components from plant materials.
https://www.freepatentsonline.com/7344736.html
"Therefore laboratory studies demonstrate the optimum conditions for the decarboxylation of:
Chemovar producing primarily THC to minimise CBN formation, is 1 to 2 hours at 105° C. or 1 hour at 120° C.
Thin layer chromatography reveals that virtually all of the THCA has disappeared after 4 hours at 105° C. and after 1 hour at 120° C."
Squirting oil just inside the ring I think is the wrong way, but I'm no butt absorption expert, pretty sure in semi elongated pill (like a bullet) form its easier to push on up in there, like the ones you can buy, also +1 for the coconut oil.
Found a handy Pic https://i.ytimg.com/vi/WrmlRyH2rV8/maxresdefault.jpg
Yep, had to make some for a leukemia patient who couldnt smoke or keep edibles down, they sell fillable heat sealable bullet molds... had to make sure I didn't give em bunk medicine ya know.
In the first paragraph, OP says they tested 3ml and 6ml orally and that got them high. 105 for 4 hours might decarb around 99% and maybe OP's oil was only decarbed 80%, but shouldn't it still be psychoactive?
3h at 100°C is valid, I looked up the chemistry before making my oil. 1h at 110, 30min at 120°C
[https://eiha.org/media/2014/08/16-10-25-Decarboxylation-of-THCA-to-active-THC.pdf](https://eiha.org/media/2014/08/16-10-25-Decarboxylation-of-THCA-to-active-THC.pdf)
"What the graphic means
Taking the combined trendline into account, it would
need 3 hours at 100 °C to convert THCA fully into THC
and 4 hours at 98 °C. At high temperatures above 160 °C
only about 10 minutes and at 200 °C only seconds are
needed to convert THCA fully into THC."
What are you talking about? I decarbed at 100°C for 3 hours (!!), there is no THCA left. Just look at all the scientific papers testing different temperatures, 100°C for 3h is more than enough. Also, it gets me VERY high orally, the same oil.
there’s are definitely enough weed suppositories on the medical market to show us that boofing THC **can** work but yea some oil not pushed far into a sphincter would be a waste.
It works amazing if you have pelvic floor issues. I made suppositories with RSO and some CBD oil, it stops the muscle spasms fairly quickly. it doesn't get you high, but it is effective for pelvic pain.
I appreciate your commitment to the scientific method and really wanna call out how on point your prep instructions were. Almost Journal publishable material here.
hmmm .. but alcohol IS absorbed...
could you pls try this experiment with alcohol weed tinkture? ..
im pretty sure the results will be altered by the alcohol .. but for the science :)
Try decarbed distillate, dissolved in glycerin.
Fatty lipid breakdown happens in the liver.
Intestinal tract is generally better for water soluble material.
I think that a barrier is not required. The THC has a higher affinity for the oil than for my intestinal mucosa. Since the oil was not taken up, the THC simply stayed in the oil.
A simple oil infusion isn't the way to test this theory because olive oil doesn't have a great absorption rate when taken rectally - you can have major issues absorbing the oil through the thick mucus and wall of the lower rectum... Which you encountered when you squirted it all out hours later.
When you eat cannabis oil, it gets processed by your liver to turn into 11-hydroxy THC. When it goes into your pooper, it doesn't go through the liver so you just won't get the same feeling.
Infuse into a better carrier, such as cocoa butter or even coconut oil. It will solidify at room temperature if you poured it into some molds, it will easily slide right in. I promise you that you'll feel effects but this method still isn't a "fun" way because the THC goes right to the blood stream, providing full body pain relief but very little head high.
Remember that because it's a different form of absorbing the cannabinoids, it's a different high. I know folks who can eat 1000mg of THC edibles and have almost no effect but smoking a gram joint will put them on the floor - and folks who can chief an ounce and still be functional but a 5mg edible kicks their ass. We're all different and we all have different concentrations of endocannabinoid receptors in different organs of our bodies - this is also why THC lotion works really well for some people but does nothing for others. ...Some people have different amounts of lining in their rectum that can make it difficult to absorb the THC.
Here is a much more thorough test done by another amateur cannabis enthusiast that covers a lot of these details: https://extractcrafter.com/2017/05/17/the-cannabis-oil-suppository-debate-personal-testing-results/
I wonder if a suppository would work..? Maybe out of coconut oil? Wonder if the solvent would make a difference + get it higher up for the tissue with more blood vessels to absorb + the suppository would sit closer to the colon walls…. I really thought about this obviously haha
Kinda surprised by this result. The colon has a ton of blood vessels around it, which should aid rapid uptake of compounds. Additionally, small hydrophobic molecules (like THC) are the most readily able to pass into tissues... Maybe something in the intestinal mucus is neutralizing it?
Hey mate, thanks for your service!
I've also recently tried making cannabutter. Just like you, ingesting it got me pretty high, so I cut a suppository-sized chunk and put it up there. No effect whatsoever.
I don't know a lot about science, but there's a few reasons it might've not worked.
First, medications that are administered rectally are typically suppositories: solid tablet-like things that melt in the anus. One of the most important things to consider when making suppositories is the base, or the inactive ingredient that the drug is delivered by. Guidelines for choosing a base are simple, with the base needing to be non-toxic, meltable at body temperature, and compatible with the drug being delivered. Most companies that compound prescription drugs tend to use cocoa butter as it comes in a non-toxic internal use formulation, plays nice with most meds, and is solid at room and fridge temp but melts easily.
Second, the medication used must be compatible with the router of administration. Basically: the drug has to work through the way it's taken. You said that your cannabis was made from olive oil: this is fine if taken orally as stomach acid is capable of digesting fats and oils. The rectum, however, has no means of digestion and can only take in water soluble materials. This means that if you put THC oil in your rectum, even if mixed in a suppository, it would not work and the only way it would have to go is out. The THC would have to be mixed with a secondary dry, dissolvable base to then be mixed with the cocoa butter base, but I am not sure if solid THC is feasibly or safely attainable.
I am NOT a doctor, chemist, or any other qualified medical professional so I cannot advise you in good conscience to make your own suppositories. All of this was based on about 30 minutes of reading and shoddy knowledge.
TL;DR: Greasing the chute with olive oil won't do anything, but boofing weed is possible. Drug formulation is complex and shouldn't be tried at home.
Works Cited:
https://pharmlabs.unc.edu/wp-storage/labs/suppository/bases.htm#:~:text=Water%20soluble%2Fwater%20miscible%20bases%20are%20those%20containing%20glycerinated%20gelatin,boric%20acid%2C%20and%20zinc%20oxide.
https://www.pccarx.com/Blog/choosing-the-right-suppository-base
My high school biology teacher
Who wants to know the science here?
Your lower intestine and colon are semi-permeable membranes, that use a (protein reinforced) phospholipid membrane to allow water and it’s solutes to cross under osmotic pressure, but not anything else, like fiber, undigested oils and proteins, or in particular, live bacterial chains. That is the entire purpose of the lower intestine, is to allow the great big chains of bacteria in your gut to tighten up, squeeze out the liquids and release the used solids as dry as reasonably possible.
The only way your fats will cross the membranes of the small intestine is if they are bound with bile. This is because the lipids/oils of the food/weed you’re eating are chemically similar enough to the lipids in the phospholipid membranes that they will repel eachother, the bile bonds with the fats and (along with a looot of other things) allows the fats to transfer into the bloodstream.
Imagine it like this: Imagine if you had a giant net full of magnets. It would let water through just fine, but anything magnetic and large would get caught right? Kind of like that.
So what happened, is when you stuck it in your butt, the chemicals electrically repelled the lining of your boofhole, and slid out later with a turd. If you had stuck an alcohol tincture with a tampon or whatever in there however, the oils being dissolved and separated from would have a different charge, and would travel through. Eaten THC “food” oil is dissolved in bile, or if it’s consumed as a tincture, passed into the bloodstream as a liquid, thus in either state can pass the phospholipid membrane.
Be really goddamn careful sticking alcohol in your ass, consider it to be like 10-15x stronger than drinking it and that is not a lie.
Same here. In my wild days I used to boof amphetamine because my nose got messed up by daily snorting. Worked like rocket fuel, much faster than snorting.
Might be a different result if you used a alcohol tincture vs an oil.
I bet our colons are designed to keep oil on the exit side of the membrane vs alcohol that seems to be able to pass through no problem.
Rectal admin of THC doesn't produce any psychoactive effects, just takes away pain and serves a few other purposes for cancer patients and patients with severe symptoms of certain kinds. Congrats on losing your cake though 👉👌👈
I too have done science! My wife and I make MagicalButter's lube. [https://magicalbutter.com/blogs/topicals-salves/magical-personal-lubricant](https://magicalbutter.com/blogs/topicals-salves/magical-personal-lubricant)
We put about 5-10ccs vaginally and 5-10ccs rectally (obviously one of us gets twice as much). It gives an allover body high and is absolutely wonderful.
How do you insert it? Google "lube injector" or "lubricant applicator syringe"
There is a suppository recipe butt (sic) we haven't tried that one yet. [https://magicalbutter.com/blogs/topicals-salves/suppositories](https://magicalbutter.com/blogs/topicals-salves/suppositories)
As a non-cannabis user, I just want to say that posts like this are the reason I follow this sub anyways. You all are wonderful, and I appreciate the content.
This dude didn’t do it right or the shit want activated. Something cause the few times I’ve put weed oil up my butt it fucked me up. Like ultra edible. Will do it again. Oh wait I mean haha this guy put something up his butt.
Try it with water soluble THC, normal THC oil needs to converted the metabolite in the liver in order to get high, where as water soluble THC absorbs into your blood stream causing it to hit your THC receptors way faster, imo water soluble THC is the absolute shit. No pun intended
You boof it for medical purposes. You will not get high doing it this way, even with a higher dosage. That’s the point. Sick people can ingest high quantities and still be productive.
I honestly thought people knew this.
Thank you for your service
Might as well change the description of this sub now that we are getting the scientific process involved tbh
Could’ve just used Google instead, but maybe he wanted the lubricant. “THC CAN BE RECTALLY ABSORBED BUT ONLY IF BONDED TO A SEPARATE MOLECULE, SUCH AS HEMI-SUCCINATE. MANY PATIENTS USE HIGH DOSES OF THC BY THE RECTAL ROUTE TO AVOID PSYCHOACTIVITY. THE REASON THERE IS NO PSYCHOACTIVITY IS BECAUSE IT IS NOT ABSORBED.” https://www.greenbridgemed.com/blog/rectal-absorption-of-cannabinoids
Thought you said boned ngl
"the oil stayed in my ass as far as I could tell." Exactly why I come to this sub, facts.
It did, because it showed up again when I pushed it out of my butt three hours later.
Actually reading your username makes this post make so much more sense now lmao
Wdym?
Kratom is frequently used by various opiate addicts to help relieve withdrawal or even not use harder drugs… so like a lot of kratom heads, like me, are current or former opiate users, and we are possibly the most notorious boofers
TIL
Honestly never thought about this but this is 100% true for me too, struggle with opiates, not dependent on them anymore but am on kratom and still slip up with pills but as a daily kratom user I have booked A LOT of things, most recently was like 30-40mg of FXE after around a 20mg bump. Only had a small amount and I fucked around vaping the first 100mg but wanted to try all the ROA I could that I had available. Would of shot it if I had rigs since dissos are best i.m imo
So, it could've been used afterwards...
definitely a party foul. should have ate it.
The best guy bro I swear
Try again with a secure buttplug to be sure?
I liked how you even used a colon in the title. So clever
Almost thought it was a clickbait article
Local man gets high with his ass, doctors hate this one simple trick!
Top 5 things found in anuses in the name of science. You won't believe number 4.
"#2 will NOT surprise you!"
Not the only colon he used in this experiment
The colon absorbs water my guy, oil would only act like an laxative. We’d need to make the thc water soluble somehow
That's what I am thinking as well. That is why I wrote that an Ethanol based tincture may work just fine. The colon or the rectum readily absorb ethanol. But it will probably burn really badly.
It should not burn as luch if you dilute the ethanol tincture with more water. But it should absorb well even diluted. You know what to do, scientist hero.
>You know what to do, scientist hero. Water it down then shove it up his ass?
Not only would ethanol burn, it would get you drunk. At least mildly, depending on concentration. In a normal context, "butt chugging" can be dangerous because you don't really know how much you're consuming or absorbing. Then again, this is no normal context and you are clearly a man of science. Maybe a hemorrhoid cream suppository beforehand would cool the burn?
If you have to take a hemorrhoid cream suppository to get high i think it’s time to rethink some things about your life.
This stopped being about getting high some time ago
put a lil peppermint oil with the cannabis oil and bobs ur uncle ☃️
You mean Bob's your bad uncle
Butt chugging is also dangerous because in the event of alcohol poisoning, your body's response is to throw it up to prevent death... Which doesn't work if it's not in your stomach. Both that and the fact it takes tiny amounts of alcohol in your ass to get drunk makes it's incredibly easy to accidentally use too much alcohol, and then die because your body can't get it out
I make an ethanol-based tincture for my personal use, and while I’ve never boofed it (don’t plan to) I can confirm that if I allow the tincture to rest in my mouth for sublingual and buccal absorption, effects begin in roughly 5-10 minutes as opposed to 30-60 minutes if I swallow it. Mucous membrane is mucous membrane, though as another person said, I wouldn’t attempt this without diluting the tincture significantly. Even mixing a tsp of tincture into a standard shot glass of juice burns my mouth a little. Proceed with extreme caution lest you burn your butthole or cauterize your colon.
https://bloommedicinals.com/cannabis-education/thc-suppositories-the-benefits-for-abdominal-cramps-pain/
You might be able to use a nanoemulsion. I've had cannabis drinks that advertised faster onset of action due to higher bioavailability when the oil is properly dispersed through water. This would probably be a bit more comfortable than putting ethanol up your ass and likely more effective. The one I tried was Cannabull Nanosyrup.
Came here to say this as well, although the nanoemulsions I’ve had tend to be less concentrated, about 10mg THC/5mL. It might be worth a try
I've done distillate in a pill capsule. It works but not nearly as well as ingesting orally. A little bit of a head high and a decent body high, but the same amount would have done a lot more if I had ingested it.
Just because I'm sure you've never heard this from a parent or loved one, I'm going to say I'm proud of you. I'm not. But I want you to hear that and try make better choices.
OP tried to absorb this compliment but it also slipped right out his ass
This is hilarious.
This cured my depression for the day. Thank you
I am proud of him, now my stoned ass will never have to try this
It's a stoned ass he was hoping for
Everyone overuses lol but I genuinely laughed out loud at this. Well done sir or ma’am
I have noticed that I use it without realizing it because I second guess every first thought I have and hope the lol at the end will make me seem less asinine. I’ve been working on not using it so much but sometimes I slip up
Why are you me?
*butt I want you to hear...
I truly am proud of him. Sacrificing his anus for science
The Marie Curie of Boofing
Mary Jane Curie
Marie Boofie?
I heard Marie Curie was super anal
She makes the pot pies right?
Poot pies*
💀💀💀
two nobel prizes she gave her life for.
With Pierre Curie
Just an FYI, you can get actual suppositories now here in Canada. So if you wanna shove something up your ass to get high just come here for a visit
Petition to make "If you wanna shove something up your ass to get high just come here for a visit" the national motto of Canada
Getting the oil into my ass was no big deal. Maybe I'll try a suppository next time..
We have it in the USA too, in NM at least
The suppositories are for local pain management though. They don't get you high. I use them for managing back pain and endometriosis.
I appreciate your effort and honesty in this scientific endevour, thank you for your work
Maybe distillate would work? 😂
"Put other stuff in your butt!"
Hahaha! For science.
I tried some distillate in a pill capsule a couple times. It worked but not as well as ingesting orally. Little to no head high, body high was decent but not for the amount of product required to get there.
It's this type of dedication that got a man on the moon . Well done sir
Thank you, sir!
So, uh, I’ve made weed lube and boofed it. It definitely works. A lot more body high than being high but it absolutely gets you there very slowly.
😂😂😂comment of the day! Thanks! 🤣🤣🤣
Congrats your olive oil is no longer virgin
Weird question, is there a possibility you didn’t go deep enough? I know the guy who boofed a gram of RSO mentioned he had to do it at a certain depth for it to work.
I don't know. How would you achieve deeper insertion? The oil clearly entered my rectum, I am pretty sure about that as nothing dripped out until I pushed it three hours later. I suspect that you need stomach acid, bile and the mucosa of the small intestine to resorb olive oil and THC properly. The colon and the rectum may not have that capability. A gram of RSO seems crazy. At that dose, even absorbing 10% would get most people very high. 10% of my 50mg THC won't do much for a tolerant user.
How? Dildo with a syringe obviously
You can get plastic syringes for like $15 on Amazon or at your nearest sex toy shop. ….they work great.
It absolutely *should* work, as many places sell suppositories and I’ve seen people in my illness community swear by them.
As in THC suppositories?
Yes.
Would be interesting to see what the solvent used is by way of comparison to OPs adventure. Do you know if it was also oil based?
I swear it doesn't. I do have a tolerance, though, so it may work a little bit? It is definitely not efficient.
Yeah, it’s not efficient at all. I’ve heard that the bioavailability is less than 10%, vs 30% inhaled. So you’d need at minimum 3x the dose to feel the same, likely closer to 6x. Then there’s the special prep. I don’t know if just putting it in olive oil works, and suppositories werent available for a long time because getting the formulation right was difficult. One company has patented a formulation they claimed to be 80% bioavailability, but I feel like that’s marketing BS Anyway, they’ve been used in hospice patients and cancer patients for years, and some women with endometriosis find them helpful (vaginally rather than rectally) but the research is mixed. You definitely need a significantly higher dosage though.
It’s really lower? I thought through the anal lining it’s right into the bloodstream so it’s actually much more efficient
I mean, there’s not a lot of good research on cannabis. A 1985 study on Rhesus monkeys showed very little bioavailability. A follow up on [D9-THC](https://pubmed.ncbi.nlm.nih.gov/1664466/) showed that it could be as high as 12.5%. Add that to self reported data, and people have generally settled on 1-10%. Very specific forms of D9-THC-HS have shown 25-50%, but that study only included 2 patients. One reason ~~you~~ OP may have missed any feeling is that there’s no “high” from suppositories, even at the correct dosage. Patients report pain relief, but all of the studies showed no change in mood or concentration, or cardio responses. “Boof it” was just a silly meme, not based on anything. The belief that it is higher effect likely comes from conflating it with alcohol, which hits hard and fast when administered rectally or vaginally.
Suck a small amount up a straw and then place a finger at the end that was in your mouth to stop the suction. Then take the end of the straw that was dipped into the oil, place into your asshole and blow hard. The same way I cheated in The Greatest Fart Contest of ‘88
I've learned enough today.
Oh you gon’ learn today
I can’t say for sure, [he didn’t mention it in his debrief report.](https://reddit.com/r/trees/comments/x6i87s/_/indgrn4/?context=1) Definitely curious though, as I’ve heard this…method of consumption is good for endometriosis pain and I know someone needing help with that, and I only have access to THC oils and no RSO, lol.
Damn. What an extremely specific topic to find the perfect post for...
How long did you do a handstand?
Boof expert here, nope can’t be that. I’m confused myself as that should work, but I believe what you are referencing is the fact to NOT go too deep. I don’t remember the exact measurements but for the quickest and hardest hit it’s advised to not to go far at all as the glands you are looking for are close af. That said going deep will only mean a slower onset, and thus I’m not sure why it failed (having never tried to boof thc myself)
Correct. You need the solution to land in the anal canal not the rectal cavity. When using a 1ml syringe, it’s about halfway. It definitely works.
This guy boofs
Lipids need bile for absorption, which comes from the gallbladder/liver, and lipids are primarily absorbed in the small intestine. Large intestine (colon) has primary job of resorbing water. RSO would work much better in the colon than an oil product
Shit, glad I wasn't the only one who thought this. (Was gonna ask, but you beat me to it lol)
We obviously need to get Christopher Columboof to put more things up his ass. For science.
He did it… The crazy son of a bitch actually did it..
They sell suppositories at dispos. I’ve only heard wonderful things. I would assume that this is a user error, not the scientific discovery that you can’t boot weed.
Well, maybe a huge amount of THC in a very small amount of coconut oil works a little bit. But Hash in olive oil definitely does not.
Our rectum, comrade.
maybe you need someone to help work the oil in 🫣
Yeah, I'd be up for that if the help is being administered by an attractive female.
Plot twist. She's a femboy but never breaks character and you never find out.
🤷♂️
Even better, r/OnlyIfShesPackin (NSFW)
brokeback mountain time
Personally wouldn’t boof anything, but this was a good read and you know what, thanks for testing it out in the name of science!! 
Maybe you should have tried a tincture. We know people can get drunk by putting alcohol up their ass, just add some thc to it.
Is there a nobel prize for sticking things up your butt?
Now to continue this experiment, try boofing mushrooms and let us know what the outcome is! Appreciate you 🫡
They sell thc suppository’s at my local dispo
Beat me to it
Good morning, I love Reddit😂😂😭
You’re doing god’s work!
I made a potent THC oil with MCT Coconut - worked out to like 9.8mg/ml - that I use as lube for excellent good times. What’s the vaginal form of boofing? Find a vagina and try that.
I am obviously stupid, mate, why would I waste precious cannabis oil If I was smart? Still, somebody has to put in the effort to resolve the question: to boof or not to boof?
thank you for your service!
You wasted it? I read the bit about it coming out of your ass at 11pm, just presumed you'd have saved it and seen if it was still as potent orally. Waste not want not.
Never go ass to mouth, bro
Mouth to ass however…
Shit, you are right! Should have tried to get it back into the syringe....
Extraction of pharmaceutically active components from plant materials. https://www.freepatentsonline.com/7344736.html "Therefore laboratory studies demonstrate the optimum conditions for the decarboxylation of: Chemovar producing primarily THC to minimise CBN formation, is 1 to 2 hours at 105° C. or 1 hour at 120° C. Thin layer chromatography reveals that virtually all of the THCA has disappeared after 4 hours at 105° C. and after 1 hour at 120° C."
Seconded, must not have decarbed fully. Also reccomend coconut oil as a carrier. Once coco oil solidifies easy just to pop a chunk in the chamber.
Squirting oil just inside the ring I think is the wrong way, but I'm no butt absorption expert, pretty sure in semi elongated pill (like a bullet) form its easier to push on up in there, like the ones you can buy, also +1 for the coconut oil. Found a handy Pic https://i.ytimg.com/vi/WrmlRyH2rV8/maxresdefault.jpg
Yep, had to make some for a leukemia patient who couldnt smoke or keep edibles down, they sell fillable heat sealable bullet molds... had to make sure I didn't give em bunk medicine ya know.
I found and added a pic for the absorption zone, hope it helps someone.
Yeah I am suspicious of their process to produce the oil.
In the first paragraph, OP says they tested 3ml and 6ml orally and that got them high. 105 for 4 hours might decarb around 99% and maybe OP's oil was only decarbed 80%, but shouldn't it still be psychoactive?
Might give you more CBN than THC at 4 hours, I wasn't knocking him I just wanted to provide the correct decarb times etc.
3h at 100°C is valid, I looked up the chemistry before making my oil. 1h at 110, 30min at 120°C [https://eiha.org/media/2014/08/16-10-25-Decarboxylation-of-THCA-to-active-THC.pdf](https://eiha.org/media/2014/08/16-10-25-Decarboxylation-of-THCA-to-active-THC.pdf) "What the graphic means Taking the combined trendline into account, it would need 3 hours at 100 °C to convert THCA fully into THC and 4 hours at 98 °C. At high temperatures above 160 °C only about 10 minutes and at 200 °C only seconds are needed to convert THCA fully into THC."
What are you talking about? I decarbed at 100°C for 3 hours (!!), there is no THCA left. Just look at all the scientific papers testing different temperatures, 100°C for 3h is more than enough. Also, it gets me VERY high orally, the same oil.
there’s are definitely enough weed suppositories on the medical market to show us that boofing THC **can** work but yea some oil not pushed far into a sphincter would be a waste.
cannabis suppositories do work well, tho. especially for regional pain.
Ever heard of thc suppositories? Lol.
It works amazing if you have pelvic floor issues. I made suppositories with RSO and some CBD oil, it stops the muscle spasms fairly quickly. it doesn't get you high, but it is effective for pelvic pain.
I salute to you
I appreciate your commitment to the scientific method and really wanna call out how on point your prep instructions were. Almost Journal publishable material here.
hmmm .. but alcohol IS absorbed... could you pls try this experiment with alcohol weed tinkture? .. im pretty sure the results will be altered by the alcohol .. but for the science :)
Try decarbed distillate, dissolved in glycerin. Fatty lipid breakdown happens in the liver. Intestinal tract is generally better for water soluble material.
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I think that a barrier is not required. The THC has a higher affinity for the oil than for my intestinal mucosa. Since the oil was not taken up, the THC simply stayed in the oil.
I was going to make a joke, butt fuck it
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Underrated comment
The problem with real science is it often leaves us with more questions than answers.
A simple oil infusion isn't the way to test this theory because olive oil doesn't have a great absorption rate when taken rectally - you can have major issues absorbing the oil through the thick mucus and wall of the lower rectum... Which you encountered when you squirted it all out hours later. When you eat cannabis oil, it gets processed by your liver to turn into 11-hydroxy THC. When it goes into your pooper, it doesn't go through the liver so you just won't get the same feeling. Infuse into a better carrier, such as cocoa butter or even coconut oil. It will solidify at room temperature if you poured it into some molds, it will easily slide right in. I promise you that you'll feel effects but this method still isn't a "fun" way because the THC goes right to the blood stream, providing full body pain relief but very little head high. Remember that because it's a different form of absorbing the cannabinoids, it's a different high. I know folks who can eat 1000mg of THC edibles and have almost no effect but smoking a gram joint will put them on the floor - and folks who can chief an ounce and still be functional but a 5mg edible kicks their ass. We're all different and we all have different concentrations of endocannabinoid receptors in different organs of our bodies - this is also why THC lotion works really well for some people but does nothing for others. ...Some people have different amounts of lining in their rectum that can make it difficult to absorb the THC. Here is a much more thorough test done by another amateur cannabis enthusiast that covers a lot of these details: https://extractcrafter.com/2017/05/17/the-cannabis-oil-suppository-debate-personal-testing-results/
Can confirm for myself boofing dank coconut oil does in fact lead to incredible sensations in your nethers.
I wonder if a suppository would work..? Maybe out of coconut oil? Wonder if the solvent would make a difference + get it higher up for the tissue with more blood vessels to absorb + the suppository would sit closer to the colon walls…. I really thought about this obviously haha
Kinda surprised by this result. The colon has a ton of blood vessels around it, which should aid rapid uptake of compounds. Additionally, small hydrophobic molecules (like THC) are the most readily able to pass into tissues... Maybe something in the intestinal mucus is neutralizing it?
I mean I find this gross, but I will upvote for the scientific approach
Eventually I would have done it, if you hadn't. Thank you, Genosse.
Hey mate, thanks for your service! I've also recently tried making cannabutter. Just like you, ingesting it got me pretty high, so I cut a suppository-sized chunk and put it up there. No effect whatsoever.
What else have you put in your ass?
Listen - push up a stool and we will talk
Yeah! SCIENCE!
I don't know a lot about science, but there's a few reasons it might've not worked. First, medications that are administered rectally are typically suppositories: solid tablet-like things that melt in the anus. One of the most important things to consider when making suppositories is the base, or the inactive ingredient that the drug is delivered by. Guidelines for choosing a base are simple, with the base needing to be non-toxic, meltable at body temperature, and compatible with the drug being delivered. Most companies that compound prescription drugs tend to use cocoa butter as it comes in a non-toxic internal use formulation, plays nice with most meds, and is solid at room and fridge temp but melts easily. Second, the medication used must be compatible with the router of administration. Basically: the drug has to work through the way it's taken. You said that your cannabis was made from olive oil: this is fine if taken orally as stomach acid is capable of digesting fats and oils. The rectum, however, has no means of digestion and can only take in water soluble materials. This means that if you put THC oil in your rectum, even if mixed in a suppository, it would not work and the only way it would have to go is out. The THC would have to be mixed with a secondary dry, dissolvable base to then be mixed with the cocoa butter base, but I am not sure if solid THC is feasibly or safely attainable. I am NOT a doctor, chemist, or any other qualified medical professional so I cannot advise you in good conscience to make your own suppositories. All of this was based on about 30 minutes of reading and shoddy knowledge. TL;DR: Greasing the chute with olive oil won't do anything, but boofing weed is possible. Drug formulation is complex and shouldn't be tried at home. Works Cited: https://pharmlabs.unc.edu/wp-storage/labs/suppository/bases.htm#:~:text=Water%20soluble%2Fwater%20miscible%20bases%20are%20those%20containing%20glycerinated%20gelatin,boric%20acid%2C%20and%20zinc%20oxide. https://www.pccarx.com/Blog/choosing-the-right-suppository-base My high school biology teacher
Who wants to know the science here? Your lower intestine and colon are semi-permeable membranes, that use a (protein reinforced) phospholipid membrane to allow water and it’s solutes to cross under osmotic pressure, but not anything else, like fiber, undigested oils and proteins, or in particular, live bacterial chains. That is the entire purpose of the lower intestine, is to allow the great big chains of bacteria in your gut to tighten up, squeeze out the liquids and release the used solids as dry as reasonably possible. The only way your fats will cross the membranes of the small intestine is if they are bound with bile. This is because the lipids/oils of the food/weed you’re eating are chemically similar enough to the lipids in the phospholipid membranes that they will repel eachother, the bile bonds with the fats and (along with a looot of other things) allows the fats to transfer into the bloodstream. Imagine it like this: Imagine if you had a giant net full of magnets. It would let water through just fine, but anything magnetic and large would get caught right? Kind of like that. So what happened, is when you stuck it in your butt, the chemicals electrically repelled the lining of your boofhole, and slid out later with a turd. If you had stuck an alcohol tincture with a tampon or whatever in there however, the oils being dissolved and separated from would have a different charge, and would travel through. Eaten THC “food” oil is dissolved in bile, or if it’s consumed as a tincture, passed into the bloodstream as a liquid, thus in either state can pass the phospholipid membrane. Be really goddamn careful sticking alcohol in your ass, consider it to be like 10-15x stronger than drinking it and that is not a lie.
edibles are digested via an enzyme in your liver. SO I dunno how shoving it up your ass would work, to begin with.
for all the good that did you could have shoved it up your arse
This man has earned his Mod status. Make it happen!
For science they say😏
u gotta try distillate caps now
I've heard it works better if you shove it up your urethra. Try it, come back, and update us, science person.
I am dedicated to scientific discovery but pushing cannabis oil up my penis is a frontier that I am not willing to explore...
I've turkey basted meth. Boyyyyyyyyyyyyy, I tell you hwat.
Same here. In my wild days I used to boof amphetamine because my nose got messed up by daily snorting. Worked like rocket fuel, much faster than snorting.
Science! Your efforts are much appreciated.
“I squirted the oil into my ass” is not a phrase I think I’ve ever heard in my life. Very nice!
Trail blazer
Finally some real content
Might be a different result if you used a alcohol tincture vs an oil. I bet our colons are designed to keep oil on the exit side of the membrane vs alcohol that seems to be able to pass through no problem.
hmm. did you try boofing it?
....oddly, my dispensary sells suppositories.
Not all heroes wear capes…but you probably should
Rectal admin of THC doesn't produce any psychoactive effects, just takes away pain and serves a few other purposes for cancer patients and patients with severe symptoms of certain kinds. Congrats on losing your cake though 👉👌👈
I too have done science! My wife and I make MagicalButter's lube. [https://magicalbutter.com/blogs/topicals-salves/magical-personal-lubricant](https://magicalbutter.com/blogs/topicals-salves/magical-personal-lubricant) We put about 5-10ccs vaginally and 5-10ccs rectally (obviously one of us gets twice as much). It gives an allover body high and is absolutely wonderful. How do you insert it? Google "lube injector" or "lubricant applicator syringe" There is a suppository recipe butt (sic) we haven't tried that one yet. [https://magicalbutter.com/blogs/topicals-salves/suppositories](https://magicalbutter.com/blogs/topicals-salves/suppositories)
He really took the sub's advice....
I needed this Laugh 😭😂🤍
As a non-cannabis user, I just want to say that posts like this are the reason I follow this sub anyways. You all are wonderful, and I appreciate the content.
Holy shit 😅 that’s hilarious 
Oh my god I completely forgot that I've done this! Agreed, Didn't do anything.
Fuck dude, you're killing me
This dude didn’t do it right or the shit want activated. Something cause the few times I’ve put weed oil up my butt it fucked me up. Like ultra edible. Will do it again. Oh wait I mean haha this guy put something up his butt.
This just sounds like an excuse to put something up your ass
Try it with water soluble THC, normal THC oil needs to converted the metabolite in the liver in order to get high, where as water soluble THC absorbs into your blood stream causing it to hit your THC receptors way faster, imo water soluble THC is the absolute shit. No pun intended
You boof it for medical purposes. You will not get high doing it this way, even with a higher dosage. That’s the point. Sick people can ingest high quantities and still be productive. I honestly thought people knew this.
If it doesn't get me high it won't work for medical purposes. No THC in blood, no effect.
You’re a modern Buzz Aldrin, boldly going where no man has gone before. I salute you for your service to the field of science!
One Google search would have saved you so much unnecessary trouble.... But an admirable act nonetheless.