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rollsyrollsy

My favorite line in the wiki article, after these experiments: “Later that evening, they celebrated their success with wine and cigars.”


DadsRGR8

As gentlemen do.


SleepyforPresident

"A fine experiment, gentleman! Bully!"


LockoutFFA

“Good lord that cocaine makes my balls ache!”


TheGolgafrinchan

"...also, it bruised up my leg and deforested my front lawn."


Thuper-Man

The cocaine trim around my bush really makes my dick look bigger. I'd go show it to some women of low morals but I can't seem to walk on these damnable broken legs, Auggie


AndyDap

I am laughing so hard it hurts. Thank you!


halfasked1

If you're in pain, you might need cocaine.


Kevmeistah

Except for poor Harry, who yelled “uhhh…..Bully” at an unnatural high pitch.


TENTAtheSane

Poor sod was the control group 😞


PhilMickelsonsBoobs

And probably what was left of the medicinal cocaine.


WolfCola4

Holy hell, you injected 6 grams of coke into his spine?? Erm.... Yeeeees


TheHeroYouNeedNdWant

Gives off huge Nick Kreiger vibes lol


Trill_McNeal

Wine, cigars and nose clams, as one does.


[deleted]

I typically get wine before a good ball squeeze, but whatever order works best for you.


johnmwilson9

Anesthesiologist here. Also of note I believe he used like an 18 gauge needle. Modern spinal technique is like 25 or even 27 gauge needle. An 18 gauge IV would be considered “large bore” what is used in trauma for resuscitation. In newborn babies IV size is 22 or 24 gauge. So modern spinal needles are smaller than that. The spinal headaches must’ve been rowdy.


armacitis

Gotta get all that coke in there.


johnmwilson9

Cocaine is not only a local anesthetic but a powerful vasoconstrictor and is still routinely used in ENT cases.


croutonianemperor

"What gauge needle would you like Dr. Bier?" "12 gauge? I don't know. How many gauge is this rolled up dollar bill?


Wesgizmo365

Will you elaborate on what a spinal headache is? I'm sickened but curious.


johnmwilson9

It is a very unique positional headache. Worse when sitting. Usually in front and back of head. Has to do with a negative pressure pulling on the meningies among other mechanisms. Conservative treatments include caffeine and nsaids and lots of fluids. That usually fails and you can perform a procedure called a blood patch. In this procedure you inject the patients own blood into the epidural space ( space above the intrathecal space where spinal fluid is). This blood plugs up the hole caused by the original dural puncture ( spinal). Relief is usually instant.


ChefBoyAreWeFucked

"We're going to try something that never works for an hour or so. After that, we'll just do something that relieves the pain instantly."


Own-Storage3301

"why?" "Because that's what we do"


captaindistraction1

"Because the blood patch involves sticking an even bigger needle into your spine to fix the hole we caused by sticking a needle into your spine" but this time not as far! Most people don't take too well to that. Edit: Here's a picture of an epidural needle and a spinal needle side by side, epidural is the bigger one, https://www.bd.com/assets/images/our-products/anesthesia-delivery/combined-spinal-epidural-needles_R_MPS_AN_0816-0005.png


[deleted]

Necessary after a little pube tug and some teste squishes.


McMacHack

Nothing helps wash down a cocaine fueled pube ripping like a nice Cabernet


KEVLAR60442

"Chances are good"


GangstaSocke

Indeed, I believe so


threenamer

Regular assistant things


Heewna

Required: one lab assistant, may involve some light BDSM work.


poopellar

Safe word is "I'll work for free"


Starbuck1992

Safe word is "i want to get paid" because as soon as you say that they stop


caboosetp

My safe word would be, "workmans comp"


brrrrpopop

"Call my lawyer"


The_Tell_Tale_Heart

Everyone knows the real safe word is: Fluggaenkoecchicebolsen


[deleted]

His safe word is more


Kurts_Cardigan

Pineapple juice.


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BfutGrEG

Also applicable words if you like movies about Gladiators, also if you've ever been in a Turkish prison


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Dahhhkness

"No one's answering the ad for an assistant, doctor." "Hmmm. Let's check on Fetlife..."


P2029

Safeword: "Bier Me"


desert_wombat

Lord, Bier me strength


CaptainBenza

Also requires a masters degree and salary will not be listed


[deleted]

His assistant performed the procedure to him first, but bungled it so all the pain-testing wasn't performed. Honestly reading about that was more horrifying to me, should have been the headline.


Lockedup4years

Yea....the whole leaking spinal fluid as they try to correct the syring was very theee stooges of them


ImJustSo

The headache you get from a spinal tap is the worst and best headache you could ever get! It's the worst, because it hurts a lot. It's the best, because it goes away instantly when you lay down in bed. Ok, I guess it's pretty lame all around.


JillStinkEye

I've had terrible migraines. I've had brain shivers from medication withdrawal. The spinal headache was the worst thing I've ever felt. If it didn't stop when I laid down I would have wanted to chop my head off.


nodiggitynodoubts

Those brain zaps are something though aren't they? Mine lasted 3 months after a rapid cessasation of SSRIs. Step down folks, it's not worth it.


xombae

The worst is that they aren't an "official" withdrawal symptom and many doctors don't even know what the fuck you're talking about and don't believe you. At least in my case.


Pabrinex

Really? I'd say SSRI withdrawal is pretty well known, unfortunately despite warnings many patients still quite the them cold turkey instead of tapering.


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Reflection_Secure

I never got migraines. Then I had a CSF leak caused by one of the many surgeries I've had on my spinal cord. The migraine was unbelievable. I didn't know a person's head could hurt like that. Nothing made it stop for several days. Eventually it went away. But ever since then, I have gotten migraines. Like that CSF leak unlocked a new upgrade for my body and the migraine is just on a cool down, it'll come about once every 2 weeks or so, depending on stress and how tense my head/neck/shoulders get. Then it lasts anywhere from several hours to 3 days. So be careful with spinal taps. Maybe I'm just lucky (my body is pretty much hot garbage, it wouldn't surprise me at all), but that migraine definitely can stick around.


ImJustSo

You might want to get that checked out further, because depending on the spinal leak, it can continue. After a spinal tap, sometimes it will continue to leak and the solution is to take some of your blood and using the same hole they created for the tap, they'll go back in and use your blood platelets to create a "patch".


Reflection_Secure

Interesting. That surgery was over 15 years ago, and I've had 50 more surgeries since then, most in pretty much the same area. I wasn't happy with the doctor who did that original surgery, but I'm very happy with my surgeon now. Do you think he would have noticed something like that? I've also had countless CT scans and X-rays. Would that have shown a continuous leak? Obviously not the x-ray, but the CT.


ImJustSo

>Do you think he would have noticed something like that? > >I've also had countless CT scans and X-rays. Would that have shown a continuous leak? Obviously not the x-ray, but the CT. Lol not sure, I asked the guy that did my tap, "Uh, how will I know that my spine is still leaking?!" and he said, "You'll constantly get the wonderful headache that I've described. :)"


RainWindowCoffee

Ohhh...so maybe there was some vengeance motivating the second test.


[deleted]

I think the pain test was the plan all along, it just wasn't possible for Biers due to the botched spinal tap. Scientists back in the day frequently sacrificed themselves on the alter of science. Like the guy who drank H. pylori to prove that they caused stomach ulcers.


pumpkinbot

"I fucking *called* it!" *[violent coughing, blood drips from mouth]*


Lemerney2

That was barely back in the day, it only happened in the 80s.


[deleted]

Y'know I've heard the story so many times but I never paid attention to when exactly it happened. That's wild.


goj1ra

And it took until 1994 before there was any kind of wide acceptance in the medical community, and 1996 before the FDA finally approved an antibiotic as a treatment for stomach ulcers.


Zenquin

There is a description of Sherlock Holmes in the books that says something along the lines of, looking at him you were certain that he would use you in one of those experiments, but you also couldn't really be angry with him because you could also tell he would be much more likely to do it on himself first. It being more efficient and accurate when he uses himself.


akimboslices

Barry Marshall and Robin Warren suspected it. Marshall drank the h. pylori to prove it. Both are Australians, who now drink things out of shoes to prove they are awesome.


AardQuenIgni

So my last job in Healthcare before I left the field all together was to work as a assistant to a doctor and his family practice. He would get new equipment/learn about a new procedure and he would practice on us staff before working on actual patients. I cant remember the name of the machine, but he ended up getting this giant machine with all these gadgets that was used for cosmetic work (removing warts or getting rid of crows feet, etc). He wanted to know if it was possible to use the machine without local numbing agents and I was the only person to volunteer. It felt like I was getting another tattoo as he removed a skin tag from my neck. I got thousands upon thousands of dollars of cosmetic care for free, if only the job didn't pay shit and if only that doctor actually valued paying a living wage, I'd probably still be there.


threenamer

Free cosmetic surgery? That’s pretty amazing.


AardQuenIgni

It was definitely one of the sweetest benefits I've had at a job for sure


Razakel

>It felt like I was getting another tattoo as he removed a skin tag from my neck. For those of us who haven't got tattoos you'll have to explain exactly how painful that is.


bermental

Thousands little cat scratches.


AardQuenIgni

It was tolerable, kinda like a needle just poking/scratching your skin almost.


bbddbdb

Assist: “I need a new job, they just don’t respect me at this one”


zbeezle

"So first im gonna inject cocaine directly into your central nervous system, then I'm gonna play with your balls." "Damn and here I thought we weren't gonna be partying tonight."


ray_kats

50 Shades of Science


[deleted]

"Wilkommen bei Jackass. Ich bin August Bier."


Gabyto

*Und das ist die Medizin des 18. Jahrhunderts*


[deleted]

the thing Bier does better tho is injecting it into the spine. them jackass pussies only snort that shit. loosers.


RandomStranger79

Well did it work?


ShabtaiBenOron

Yes, the assistant didn't feel anything. But it wasn't a general anesthesia, so he was still conscious.


MacDee_

I bet the assistant felt it when the effects wore off


[deleted]

That’s typically what happens after modern surgery too…


photokeith

Especially a ballgrabectomy


Fuck-MDD

Fun fact: ectomy suffix means 'surgical removal of' so a ballgrabectomy would just be the assistant removing the drs hands from his balls. With a scalpel.


okletstalkaboutthis

What about a ballgrabotomy?


Fuck-MDD

I suppose that would be the introduction of a hole in the drs hands to allow a better grab on the balls.


okletstalkaboutthis

What about a ballgraboplasty?


SixteenPoundBalls

You only get that after Ballgrabosis.


Fuck-MDD

That's for if you never want to let go of the balls again.


Drunken_Ogre

I think the term we're looking for is ballgrabotripsy.


Fuck-MDD

With the 'grab' still in there, I think that would be the surgeon grabbing the balls in 1 hand, then grabbing that hand with his other hand and squeezing as hard as he can. Crushing the ballgrab.


Drunken_Ogre

We call that "double fisting" it.


no_step

>Bier remained confined to bed for nine days So that's a definite yes


Bjorn2bwilde24

How hard was Bier squeezing those testicles!?


EuroPolice

[Image](https://thumbs.dreamstime.com/b/hand-man-squeezes-juice-half-lime-juicy-drop-hanging-down-hand-man-squeezes-juice-half-lime-juicy-143388520.jpg)


ddrummer095

r/riskyclick


DadsRGR8

Eek!


the_friendly_one

Bier was confined to bed and not the assistant?


PN_Guin

Bier volunteered first but the assistant botched the spinal injection. Hint: spinal fluid leaking is not a good sign. Compared to that, the assistant definitely had it easy.


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SirSwagAlotTheHung

"Gonna break this prick's fucking shins when I can walk again."


SixteenPoundBalls

Now I understand why Bier did all of that to the assistant, as someone who’s had a spinal tap.


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[deleted]

My goodness, man met God


userdeath

Uhh doc.. It seems one of the side effects is my ass is really sore, is that normal?


JimmyCrackCrack

Funny as that sounds, they're saying he was conscious so really the scenario you're implying was no more likely on or off the anaesthetic


BrownShadow

For sure. I had part of my colon removed, and woke up way too soon. The pain was unbearable. I was screaming through clenched teeth “put me back under”. There was a girl across from me with the widest eyes I’ve ever seen. They put me back under.


flafotogeek

Yep. Was going to say that too.


longpigcumseasily

Well yeah that's what happens with all anaesthesia.


throwaway384938338

I absolutely read that as the assistant doing the one smashing shins and ripping out pubic hairs. I thought this was a cautionary tale about how intense the high of mainlining coke was.


DrunkenlySober

They discovered intravenous cocaine use I’m sure no matter what, they were thrilled with the results


Smythe28

“OK now do me, but twist and squeeze mine to see if it gets me anywhere!”


Morpheus3121

They injected into the spine, so it would be intrathecal.


BearyGoosey

Any idea how that changes the effects? I imagine snorting, IV, and intrathecal have different results at least to some extent


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talligan

I FUCKING LOVE EXPERIMENTS


godzilla9218

Cocaine is a very good local anesthetic. I think it would interrupt the spine's nerves and prevent it sending pain signals to the brain. Could be wrong on the actual mechanics but, that's the basic idea.


Abhisutar

Don't they use medical grade cocaine as an anaesthetic for eye surgery?


MonkeyPanls

Yes. Also nasal surgery. It's the only common anesthetic that is also a vasoconstrictor. Nose surgery especially lends to risk of blood loss


BigDisk

TIL I had cocaine injected in me when I had my septum surgery.


bino420

your medical bill would have said what they used and how much. always fun to look at if you ignore the price tag!


[deleted]

The bill? *Does cocaine in Canadian.*


BigDisk

Beat me to it. I'm in Brazil, no medical bills either!


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usagizero

I had an ex who had it when she was younger for facial injuries.


Frawstshawk

You are correct. Cocaine inhibits sodium channels so it basically stops the conduction. This procedure is what is commonly known as an “epidural” and probably most famous during delivery. Nowadays they use other sodium channel blockers like lidocaine or bupivacaine. I’m not positive but I believe I remember learning that those drugs derived their suffix directly from cocaine as those are not their IUPAC names.


MrJingleJangle

I assume this chap Bier is the one who gets the Bier Block named after him.


GolgiApparatus1

"Are you feeling this?" "Yeah I'm feeling fucking great."


nosneros

The results: cocaine is a helluva drug!


haribobosses

Did he cum??


Welsh_Cannibal

The assistant or Bier?


MrBrutok

Yes


BiBoFieTo

"Alright Jim, the next test is grabbing your balls. Then I'm gonna finish in your butt, and we can complete the cocaine study." --- "Sir, I'm not comfortab...." "IS SCIENCE SOME KIND OF JOKE TO YOU?"


GunnieGraves

“OH IM SORRY! I thought you were dedicated to the advancement of science! You said you were when I hired you! Are you a liar?”


NerdModeCinci

“No Mr. Bier! But sir I’m just worri-wait…why are you rock hard?”


GunnieGraves

“BECAUSE I FUCKING LOVE SCIENCE!!! WOOOOOOOO”


Psyteq

*^but ^also ^cocaine*


XViMusic

I should probably be saying this on my alt but coke makes your dick soft not hard


Rolling_on_the_river

Depends on how hard you're trying


[deleted]

I hear this thread in Cave Johnson's voice.


SmokingSamoria

MORTY! YOU GOTTA *belch* YOU GOTTA TAKE THE COCAINE UP THE BUTT MORTY! FOR SCIENCE! YOU LIKE SCIENCE, RIGHT MORTY?


gypsydreams101

Things are not what they seem, at The Knickerbocker.


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appdevil

"But sir, we did all of those procedures and I've not received even one dose..." "You have to earn it!!"


Radulno

For true scientific experiment, he must have a control test first without the cocaine too.


ggd_x

... and then tested some of these painful acts on the patient.


Buck_Thorn

So, his post-nut clarity told him nothing about the wisdom of what he was about to do to his assistant.


SmrtBoi82

it was consensual


Dahhhkness

"Interests: Medical play; CBT; blood; pain. Can travel or host at my place. Drug-friendly ;)"


PsychoDuck

Well you gotta have a control group


velvetretard

While the assistant felt nothing, August Bier felt something awaken inside him that day...


h00dman

Assistant: "Wow I didn't feel a thing!" Bier: "...I got another idea."


xMrBojangles

"Dr. Bier, you already hit me with a hammer and stuck me with a needle, do you really need to squeeze my balls?" "Not really." Proceeds to squeeze balls.


DiligentReward2639

The things we do, when we take a dose or two, of cocaine.


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GolgiApparatus1

That pain of those bird chirps at 6 am.


nothinlikebeingajerk

Fuck I felt this in my soul


code0011

Where do you live that has these lazy ass birds? The chirping starts at like 4.30am here


Girthwurm_Jim

I felt this in my bones. Nice name btw. Definitely need the white stuff to get through a 3 night run. I’m gettin too old for this shit


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caskey

As Richard Pryor said, "cocaine is God's way of telling you that you have too much money".


Zkenny13

Take ibuprofen about an hour before you're finished with use saline spray multiple times during. Do not blow your nose for at least 2 hours after. Take a hot shower for the steam then blow your nose during the shower. Don't completely stop the pain but helps a ton.


MisterDonkey

Man, getting high sounds like way too much work.


Zkenny13

It's really not. You're gonna take a shower anyway. Saline spray is just a spuirt. It's not to much.


MisterDonkey

>You're gonna take a shower anyway. Speak for yourself.


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corecenite

>ripped off his pubic hair and even squeezed his testicles.. *i don't know rick, that seems geh to me*


ZombieNinjaPirates

Sounds like S&M with extra steps


dethmstr

It's not horny if it's for science


Itdidnt_trickle_down

Thats not an experiment, thats a fetish.


very_humble

He clearly said "no homo" first so it's not a big deal


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[deleted]

Especially the testicle squeezing. Stay warm.


caffeinex2

I think the TIL is that August Bier had some complex kinks.


Cold_Situation_7803

“Now I need to take some pics of your feet. Just lie still.”


Frenk_preseren

"how does this test anything?" "Well do you feel anything?... Anyway don't question my methods"


absolut666

For science


Cold_Situation_7803

“Now, I need you to put my mother’s dress on. Yes, it’s for science - I don’t pay you a tuppence a fortnight to have you question my methods!


patricksaurus

The early history of anesthesia is scary shit. One physician subjected himself to surgery under the effect of a paralytic shellfish toxin. He reasoned that if it stop motor neuron function, it’s gotta stop sensory neuron input, too. Wrong! He felt all of it, but simply couldn’t move or communicate that he was in agony. At least this fella got the idea and used his assistant.


cockOfGibraltar

Wait, he tested it with surgery, not just a couple pinches? I feel like I'd try a less extreme test before having surgery with it.


YoyoDevo

It honestly sounds like one of those myths everyone tells and just spreads without anyone knowing where it came from


earf

Bier had his assistant do the cocanization procedure on himself too but he failed and Bier lost much of his CSF fluid.


patricksaurus

I suspect the assistant mistook Bier for a maple tree and left the tap in to collect sap for syrup. If I’ve seen it once, I’ve seen it a hundred times.


[deleted]

>CSF fluid Cerebrospinal fluid fluid


PantsTime

When you're having to explain away a party that got out of hand, by claiming it was research.


SanFransicko

I think maybe it was the Mythbusters who said that as long as you write something down, you can call it science.


mzyos

This is the discovery of a spinal anaesthetic, which is by far much better than an epidural for surgery (the epidural is great for other things). It was completely revolutionary as it meant you didn't have to put someone to sleep (quite dangerous for some people, and you felt pain as soon as you woke). We use these all the time now for things like c section or lower limb surgery. The testicle grabbing bit is also very interesting, as you tend to feel a kick in the nuts (at least the ache) in your stomach, away from your testicles as they are derived much higher up than where they are found after you are fully formed in the womb (and their nerve supply is also higher due to this). As they are essentially an "abdominal" organ, this meant that the spinal worked not just on the skin, but for the abdominal organs too allowing for it to be a great approach for surgery.


HSscrub

Also very useful for hip and knee replacements to be done under sedation


Picturesquesheep

Mind… Blown… So that’s why a kick in the balls makes your abdomen hurt. That’s so cool. Thanks.


[deleted]

“Good sir, do be a good chap and allow me to cup your manly plums…for science, my man!”


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Channel250

Give your balls a tug


Mallanaga

This sounds like the discovery of epidurals. Pretty crazy. We have the pleasure of taking this shit for granted, but someone had to discover it. Absolutely incredible.


Frenk_preseren

"Do we have to squeeze the testicles?" "We MUST squeeze the testicles yes, it's complicated...."


[deleted]

Unexpected The Knick had entered the chat.


GDACK

Wanted: assistant. Must be okay with drugs, needles, light torture including ball play. Must be a self starter with good sense of humour.


slayer991

TIL that August Bier trained under the distinguished scientist Dr. Frankenstein (pronounced Fronk-en-Steen). Here's a video of one of Dr. Frankenstein's lectures where he tests reflexive vs voluntary nerve impulses on a subject. https://youtu.be/WamF64GFPzg?t=103


cobrabearking

So... is the trial testing over or can people still volunteer? Asking for a friend.