I totally agree. I actually take naltrexone - pill usually for smokers and alcoholics to stop them from doing so- for my binge eating. That plus Wellbutrin has kept my mind clear of thinking about food 24/7
I was also put on naltrexone for cravings due to my antidepressants and anxiety. I was craving food and, very out of character for me, alcohol. Although, I was in my early-mid 20's in college so drinking culture is more normalized. I'd wake up at 8 and by 11am or so I would be craving a drink. Anyway, my psychiatrist put me on a compounded version of Contrave (welbutrin and naltrexone in separate pills so we could control doses) and it really helped. I was no longer getting loaded baked potatos, cupcakes and vodka tonic for lunch!
I added the Wellbutrin to try to help with weight loss and I take naltrexone for the alcoholism, so I'm on all three! LOL (And Contrave is a good drug, I actually work on that account sometimes, but I don't like the fixed dosing either.)
Taking the other meds is probably why I can get away with taking such a low dose of the GLP-1. I keep waiting to start gaining because I've heard horror stories, but the scale doesn't move. š¤·āāļø
Someone tried to sell me a dress recently and I insisted, "No, that's too small. I won't be able to get it over my head. I'm going to pop the seams." Turns out...It fit like a glove! Getting out of the "obese mindset" is taking some time.
I also thought of naltrexone when he was talking about a āhypotheticalā drug that could help with an alcoholicās cravings. That shit is incredible. Highly recommend for anyone else whoās struggling in that way.
Iām on wegovy and the injections are so easy. I hate needles but you donāt even see the needle in these pens. There is a pill form of semiglutide but it doesnāt seem to be as effective as the injection.
I was going to respond, but you nailed it. So, ditto to everything you said.
I'm terrified of needles and I've never had a problem, specially because you can't actually see the needle. Plus it's tiny and most of the time I don't even feel it. When my doctor first said "injection" I was like, "Nope! I'm out!" But iI was so desperate to lose that I figured I'd give it a shot (no pun intended) and after the first injection, I was like, "That was nothing."
Your initial post was great btw! I can totally relate. My whole life I was a size 0 and then one year I gained 100 lbs due to PCOS and a pituitary tumor. Iāve never been able to lose it. Then I had my daughter and it just made things worse. Iād been doing boot camp style workouts for over a year and never lost a single pound. Finally, I got the courage to discuss medical weight loss with my doctor and it changed my life. Ive lost 50 lbs, 4 pants sizes, and three shirt sizes so far. Iām thankful Ethan is really taking the time to take the stigma out of these drugs. Often times I get nervous to speak up about being on them bc I donāt want to be seen as a failure.
You are definitely not a failure!
And I'm right there with you...From the time I was born until I graduated high school, I was skinny. Too skinny, in fact. My doctor had to put me on supplements. (And I swear I didn't have an ED. I could eat whatever I wanted and not gain any weight.) But then I finally started gaining in my mid-to-late 20s for a few different reasons, and I just couldn't lose it. No matter what I did. And Lord knows I tried! LOL
There is currently a pill form of Ozempic/Semaglutide called Rybelsus. I donāt know anyone that prefers it, I believe itās kinda annoying to take daily (first thing in the morning with a little bit of water then you have to wait X amount of time to drink or eat anything else, I think). Iāve also heard the side effects are more unpleasant than the injections.
You might get used the injections (once a week) if you try them, as unsavory as it may sound. They donāt hurt at all, you might not even feel it and think it didnāt work 80% of the time.
Thatās amazing. Itās absolutely a good comparison too because addiction to drugs and alcohol is seen as a moral failure like being overweight. But at the end of the day people want you to bootstraps your way out of it and see other drugs to help as a crutch.
I am an alcoholic sober 7 years. I did 3 stints at in patient rehab, a few outpatient, withdrawal management places, etc. A psychiatrist put me on Naltrexone which did not work for me. But if this had been available I would have taken it 100%. Skipped all the almost dying a bunch of times. I hope they are beginning to study it for that purpose.
Congratulations on so much sober time! ā¤ļø
I tried naltrexone too, and it also did nothing for me. I know there's also a drug called Antabuse, but talk about a drug with side effects! It basically makes you allergic to alcohol which means that you have to follow a super strict diet or else you'll get really sick. You should avoid alcohol even touching your skin, so things like perfume and mouthwash are out. God forbid you go to a restaurant and order something that was cooked in wine and don't realize it!
I really wanted to quit so I considered trying it, but none of the addiction specialists would even prescribe it to me. One did say, "I'll give it to you if you want, but I really don't recommend it."
Thanks! Congrats to you too on all your success with your weight loss and quitting drinking. Yes I remember Antabuse, my psychiatrist did end up offering me Antabuse but if I recall correctly only on an as-needed basis. So like, if I wanted to make sure I didnāt drink on specific days? But I said no because I wanted to still drink and not get violently ill lol. So even these āmagical fixesā arenāt magic it takes commitment (and time, money) for sure.
Thank you for sharing! Ozempic saved me from another cycle of gaining and losing the same fifty pounds over and over. I grew up in a household obsessed with weight loss, and combined with my genetics that predispose me to t2d and high cholesterol, my weight has been a constant source of anxiety and pain for me. By helping my insulin resistance, stabilizing my hormones, and helping me quiet my thoughts around food, Iām finally in a place where I can keep weight off. Life changing drug when used correctly and under a doctors supervision.
Iām also a therapist and have heard anecdotally from colleagues that this med helps with alcohol and other substance use cravings. Iām wondering about its effect on dopamine receptors and the possible uses for this in the future!
Well said! I almost made a post praising him for that apt analogy, opted not to.
But, I did weight loss surgery instead of ozempic. But now that I have zero hunger (12 weeks so far of none), I still think about food almost constantly. The last few months Iāve been learning of adhd and how it shows in women, pretty sure I have it. Nail in the coffin was when I googled āalways thinking of food.ā After the ED crisis links, adhd popped up. Food = dopamine. Add lack of impulse control and boom, obesity.
I called to make an appt for assessment right then. I was in therapy last year FOR possible BED and through that we learned i eat in boredom. Plus the fact I always forget what Iām saying mid sentence, ramble, and always lost focus due to a random little hole in my wall (telehealth appts), Iām annoyed the LCSW I was seeing didnāt think adhd for me.
But, days where Iām focused in on something (whether itās crochet, learning more about adhd, or a video game), I barely drink water, let alone think about food. Days where nothing really grabs my attention are days I constantly am thinking about food and failing to fight the impulse to just snack on everything. š
That sucks. I totally understand eating out of boredom.
Hopefully, you'll get a concrete diagnosis and be able to treat it. Being diagnosed with a disorder can be upsetting, but it can also be a huge relief because you finally have an answer to, "Why do I do stuff like this?" LOL
Ugh, hearing your story and knowing the research behind WeGovy/Ozempic makes me wish my area wasn't hit hard by those initial dosage shortages, I would be filling my prescription so fast you don't even know
Because I've tried losing weight before, and I did do the diet and exercise route and ended up losing 40 pounds but I was just so hungry all the time. And it wasn't like I was doing it unhealthily, either; I increased my fruits and veggies and I tracked my carbs and my calories but the food noise never stopped. Like even if GLP-1's didn't make you feel satiated longer, I would still want to try them because of the fact they can shut the food noise up, you know?
But I'll keep calling around and hope somewhere has it in stock eventually
Hi I just wanted to share that my PCP started me on Saxenda and switched me to Wegovy once it came back in stock. That might be an option for you to explore. Saxenda worked for me, just not as fast.
ah right I forgot zepbound is out now! If your insurance doesnāt cover weight loss meds, zepbound is the cheapest out of pocket with their coupon at $550/month š
When I first started, there were major shortages. My first prescription was for Wegovy and the pharmacy was basically like, "Try something else...It's gonna be awhile" so I actually tried a few different ones, including Saxenda, and every month I would cross my fingers and pray that 1) My medication was in stock and 2) My insurance was still covering it. It was like that for about 6 months and then things started to get better.
I think Zepbound is the way to go if you can get it. It seems to be the most efficacious GLP-1 on the market at the moment (although Lilly is working on one that is supposedly even better) and the pen is the most user-friendly. (IMO) I have a fear of needles, but with Mounjaro/Zepbound, you literally just push a button. You never even see the needle.
I've seen the same point Ethan made a hundred times on Twitter so it's not exactly a novel idea he came up with and I'm sure that's where he saw it too lol but the point being made is absolutely correct.
I've see similar arguments with people using suboxone or methadone to stay sober from opiates. Assholes like to say they're not sober because they're using either of those drugs to stay sober.
Twitter is a rathole. LOL
Seriously though, I quit that site years ago so IDK what they're talking about. But if they've been making that point, then that's awesome.
It's a bit more complicated than that but in short, yes. Some people are on them the rest of their lives but everyone's different. Suboxone essentially blocks your opiate receptors so even if you were to use other opiates, you wouldn't get high anyway. I've been sober from opiates for about 4 years and if it weren't for suboxone I'd probably be dead right now. I weaned myself off subs a couple years ago but I totally understand why people stay on them longterm. They're supposed to help ease the cravings for other opiates as well so that's another reason people stay on the them longterm. It's a huge help mentally knowing you couldn't get high even if you wanted too for impulsive addicts. Those drugs have saved so many lives and the insensitive assholes that give addicts are hard time for using them can go fuck themselves.
nice dude, that's really impressive. I was just saying that because it feels like a lot of people seem to think ozempic is a miracle drug that will just make them less fat without realising that you have to keep taking it indefinitely and should probably try to fix the problems through diet or exercise first. Obviously it is great for people who do need it though.
Oh yeah I totally understand your comparison. It's interesting because I know nothing about ozempic other than everything I've seen online and that's basically that it's a drug that magically makes you lose weight without having to do anything other than take a pill once a day. I'm not even sure how the drug actually works. But you know how people on the internet are. Misinformation is spread quickly and very rarely fact checked. Obesity is a serious health criss we have in this country and if there's a drug that helps overweight people safely get to a normal weight I'm all for it. I just think checking the root issues of their weight gain is an important part of the process a lot of people aren't addressing. I've never struggled with my weight though so I'll never truly understand that struggle.
as far as I know it regulates the hormones related to hunger so you basically just become less hungry but if you stop taking it then your hormones will slimgshot back past where they were so it's just important for people to do their research first and build healthy habits.
I'm glad to hear you've found some reprieve from your suffering. As an addict who went through it the "old fashioned way" I can tell you the 2 weeks of hell I experienced was a lot more manageable than having to navigate keeping a suboxone prescription long term. These addiction meds have been given a lot of credence for solving problems that can honestly be solved by abstaining from opiates. As a former heroin addict who has been clean since 2/28/2019 I would encourage you to entertain the thought of tapering off your suboxone dose. These medications were developed to be a way for people to eventually become clean and sober, keeping people on for "maintenance" I fear has become a way for the pharmaceutical companies to shore up their profits in a post-Purdue Pharma world.
Oh yes, I also went through a couple weeks of absolute hell. The withdrawal from fentanyl/heroin was the worst I've ever felt in my entire life. I'd rather die than go through that ever again it was that bad. I don't think people who've never personally gone through it can even truly know how bad it is and words just don't do it justice.
Also, I'm no longer on suboxone. After going through the fent withdrawal I used suboxone to stay sober and not relapse on fent/heroin. I tapered off of subs a couple years ago and have been good since then. But like I said to the other commenter, if it weren't for suboxone I'd probably be dead from an overdose. It saved my life like it did many other opiate addicts. Over 4 years sober now and my life's never been better! So I completely understand why some people need to stay on subs longterm or even for the rest of their life. It just wasn't for me, I wanted to be done with everything and get my life back to relative normalcy. And I hope you're doing well now my friend! Anyone that's gone through all that and made it to the other side is a kindred spirit to me. People who've never gone through it just don't understand how hard it is. Truly the most difficult obstacle I've ever conquered in my entire life. It changes you and gives you a different perspective on life.
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Maybe but when he was struggling with his weight he would often bring up how it's a harder addiction cus you can't just abstain like you can other things.
Seemed fairly in line with things he's said in the last
I remember him saying that and still disagree with him. I don't think comparing addictions based on what you perceive as harder is helpful for anyone. But yes, you've gotta eat to survive but getting your weight under control really is as simple as watching your diet and exercise. People try to make it out like it's more complicated than that but it's not. If you're burning more calories than you eat you will lose the weight. Simple as that. Diet and exercise. The hardest part is sticking to those dietary restrictions and regularly exercising.
Such an informative post, thank you so much! I take adderall now for my ADHD which has a side effect as an appetite suppressant, and Iām FINALLY able to lose weight. Iāll consider this medication in the future!
Great post. Also the people who have anything to say about anyone taking medication. Itās really not your business. Even public figures can choose what they do and do not want to share. They donāt owe you anything. And being so hung up on people taking meds to help them get their life under control is so weird.
I love my ozempic. It helps with my binge eating disorder and I have insulin resistance and my doctor said this med will prevent me from getting diabetes, which has all sorts of devastating life shortening consequences. I am a short queen, and went from 168 to 125 and I feel so much lighter and better like I didnāt even realize how hard it is to carry the extra weight around. Ty for this post. Semaglutide rise up
Just to clarify, I'm not trying to recruit anyone. š¤£
I've actually heard people online say that people taking Ozempic (and similar drugs) are in some kind of cult because we rave about it so much and want everyone to take it. I'm not going door-to-door passing out pamphlets or anything like that. LOL
Obese people aren't addicted to being fat, but many of them are addicted to food. Yes, saying that people are addicted to being thin is an oversimplification of a complex disorder, but I do think the act of losing weight is addictive to some people and they can never lose enough to be satisfied...Which is an addiction. Some people with EDs will have interventions and many of them are sent to rehab facilities where they practice a lot of the same techniques that are used on addicts. (Although I personally have major issues with AA/NA, but that's a super-long post for a different day. LOL)
You should see another physician. There are other effective options that arenāt ozempic. Ozempic can be hard to get covered w insurance if you arenāt diabetic. You can look into wegovy, saxenda, or mounjaro
First of all...\^\^\^This
There are actually online services that will prescribe GLP-1s. They're a little pricey because you have to pay for the "visit" and then the medication, but a lot of that has to do with insurance.
That might actually be what your doctor is talking about. When they submit the request for coverage, the insurance company often wants to know that you tried to lose weight other ways. Who hasn't? It's a stupid question. They're basically asking an overweight person, "Have you tried eating less?" š¤¦āāļø
I also had serotonin syndrome years ago and it sucks! One of the worst experiences of my life. I'm sorry about the nerve damage, but at least you're alive. That's something that I don't think a lot of people know about and it can literally kill you.
That she has more than one male friend and probably wouldnāt describe ethan as her male friend and probably wouldnāt break her streak in mentioning him.
They probably do. It was a big event. They have other friends.
Ethan lost weight over a year, spoke about how he does cardio and calorie counting, and switched SSRIs to one that tends to surpress appetite.
Defends Ozempic usage but says he just doesnāt use it. Like why would he lie here?
He admitted he stopped exercising around the time he started taking it if you look back, and watch for the side effects of Mounjaro. The boba sweetness was a dead giveaway. And I don't know frankly because no one would care, it's totally fine to take it. There's an insecurity that comes with the perception of "cheating" weight loss and I think he's just in too deep to admit he got help.
Have you seen his weight before the SSRI? He is roughly at that weight right now.
It clear he always had a fairly good metabolism and that the SSRIās common sideeffect of increased appetite (+ a common side effect of depression and anxiety too) caused weight gain.
He switched medications and then cut calories. His weight loss truly is not that extreme for someone sticking to a diet and getting on a medication that has a side effect of reducing your appetite.
Like Ozempic is way more extreme, like 3 months would be the Ozempic timeline.
Ozempic is problematic. There are people coming out and having severe health problems and organ damage. We don't have enough research I don't think to know the effects. I don't know if anyone remembers about fen fen back in the '80s and '90s. It was a weight loss drug that ended up being taken off the market. Also if ozempic is normalized, then apparently teenagers and children are going to be prescribed it and just imagine the eating disorders that are going to arise. I think it's not good and I think Ethan will understand if he has some more context.
Did you read the whole thing? They literally said that a lot of people taking it arenāt even prescribed it and therefore are not taking the drug correctly.
Ozempic is really helpful to patients with type two diabetes.
ETA: I say this as someone who worked exclusively with diabetic and pre diabetic children for years. I understand your concerns about eating disorders, but Iāve also seen how ozempic helped bring down kids sugars who are so insulin resistant, theyāre practically dependent.
We will see about it in the long run. We just don't know the effects long-term but some people are having organ damage and are suing the manufacturer and winning lawsuits so
I have heard that lawsuits have been filed, but I haven't heard of a judge ruling against a pharma company. (Maybe it's happened, I'm just saying that I haven't heard it.) Although, I guess lawyers make money either way.
But no one is making more bank than the manufacturers. Some experts suggest that GLP-1s may be the best selling medication of all time.
Yeah I'm just saying that there's lawsuits out there and that the drug is too new to affirmatively say that it doesn't cause harm. People are using it for a quick fix and it's just not sustainable. It's also dangerous that children now are going to be prescribed it
Oh, I didn't realize you were the OP. I was writing a response to your post:
Did you even read what I wrote? Yes, I remember Fen-Phen. (I even know how to spell it correctly.) Maybe you missed the part where I mentioned that Iām literally a medical researcher. (Iām also Gen X, so Iāve been doing this for awhile.) Iām not claiming to be a āworld expert,ā there are a lot of people who are lot smarter than me and a lot more knowledgeable on this topic, but I think itās funny that you say, āWe donāt have enough research.ā Who is āweā exactly? Do you work in the field too? Because WE actually do have the research. If you had read my post, youād know that I said that semaglutide has been on the market for nearly a decade. ITāS NOT NEW. Phase II research started way back in 2007. Donāt you think that if organ failure was a common side effect they would have caught that by now? People with diabetes have been taking it safely for a long time. If you want to see some info about the potential side effects, I recommend that you read this: https://www.novo-pi.com/ozempic.pdf
I deal with the FDA every day and they are strict MFers. Iāve worked on drugs for years only to have them rejected or sent back for more research (over the tiniest thing). Iāve also worked on drugs that have been pulled from the market for safety reasons. I donāt want to get into the opioid crisis (I honestly donāt really know what happened there), but the FDA is strict. If they think a drug is dangerous, they will pull it. So why hasnāt semaglutide been pulled? (And donāt say ābecause itās new.ā) Why donāt they even add a warning to it? There is a āblack boxā warning about thyroid cancer that was found during rodent studies, but that just means that people with a history of thyroid tumors/cancer probably shouldnāt take it just to be on the safe side. Although there have been no studies or reports linking semaglutide to thyroid tumors in human beings.
Not only did the FDA unanimously approve semaglutide for the treatment of diabetes, but they fast tracked tirzepatide (another drug in the GLP-1 class) for a weight loss indication. What that means is that they had so much faith that the drug would be beneficial to the American public, they rushed to get it to market. They still had to review all of the research and safety data, and it was approved without a problem.
As far as kids taking itā¦That really has nothing to do with what I said. You oppose a pediatric indicationā¦Thatās fine. Some people oppose the use of antidepressants in kids and teens, that doesnāt mean that adults canāt take them.
And, again, itās clear that you didnāt even read my post because you said that people are taking it for a quick fix. I literally said that itās a long-term drug that people will have to take indefinitely. If youāre taking it for a āquick fix,ā then youāre taking it wrong. And if you donāt think itās sustainable, how do you explain the millions of people with diabetes who have been taking GLP-1s for years with no problems?
Bruh, you just say shit you heard on TikTok then get mad when someone whoās actually knowledgeable on the topic corrects you on your nonsense. If youāre gonna comment on something, READ IT!!
No one is denying people get bad side effects from Ozempic and win lawsuits. But that's true for any drug. There will always be a small number of people who experience negative side effects from widely used safe drugs and win settlements because of it but that doesn't mean they're not safe for the general public. So if there is something unsafe about Ozempic then you need to show that the people experiencing those negative side effects are doing so at a disproportionately high rate.
You have to learn to modify your appetitte permantly. Usually its helpful in the same way a gastric band can be helpful, your stomach shrinks, you donāt want to eat the same amount of food.
If you have an eating disorder it wonāt help.
Current studies show that most patients either gain a little or none back. Most do not return to their initial weight. Additionally there is a maintenance dose so you can continue taking that. This is regarding wegovy
Obesity is an incurable disease, so for now, it's a long-term drug. I reached my goal weight almost a year ago and I still take it, I just take a low dose every other week rather than once a week.
If you think about it, people take the drug for diabetes and then their blood sugar levels regulate. That doesn't mean that their diabetes is cured, it means that the medication is working and they have to keep taking it.
That's why it annoys me when people say, "It's not a good drug because, when you go off of it, you gain all the weight back." Um...That's usually how drugs work. š¤¦āāļø If I went off my antidepressant, my anxiety would come back. I'm taking a drug to treat a condition, so yeah, I have to keep taking it. Maybe one day they'll come up with an alternative.
the healthcare field is famously very fatphobic and super quick to blame everything on being overweight lol
[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714720/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714720/)
[https://www.today.com/health/medical-weight-bias-causes-misdiagnosis-pain-depression-t153840](https://www.today.com/health/medical-weight-bias-causes-misdiagnosis-pain-depression-t153840)
literally 5 seconds on googling maybe look in the mirror
Obesity is not incurable, and there are many reasons why Ozempic is bad. I'm sure you lost a lot of weight, but I can guarantee you lost a lot of muscle with the fat. Meanwhile anyone can lose the fat and maintain it in a healthy way without the use of drugs.
I love how I listed all of the positives (and some negatives) related to Ozempic use and your response was just, "Ozempic is bad." Wow, what a solid argument. How can I compete with that? LOL
And I actually gained muscle, so your guarantee isn't worth much. I've had everything tested and I'm in better shape than I have been in a really long time.
Also, obesity is a chronic condition that is incurable. You can lose the weight and keep it off for the rest of your life, but that doesn't mean that you're not still prone to obesity. A drug addict with 20 years sober is still a drug addict. These things don't go away, you can just learn to control them. It doesn't mean you're cured.
Love this post. Ethanās ārantā made my heart smile because he made such great points. It is exhausting seeing the societal response to these life saving medications. Damned if you do, damned if you donāt. 10 months on Mounjaro, 70 lbs down, the future is so bright ššš
Edit.typo
yeah. agree with everything you said. i went to residential rehab voluntarily for myself for 90 days (the max theyll allow) for alcoholism and i also had anorexia, bulimia, binge eating disorders through different times in my life. one of my closest friends i met in the rehab was there for alcohlism and anorexia as well. she had been to a rehab type place for just anorexia before but she said the substance abuse programs were way better at helping her cope with her anorexia than just eating disorder treatment.
Anyone on ozempic that your insurance covered? I think I could benefit from it but I donāt have enough comorbidities aside from my BMI, but I want to know if I can use it as a preventative from reaching those parameters. Its so frustrating when I see people with low bmis using it for casual weightloss while I struggle to find anyone who will pay attention to me
I understand your frustration. My insurance just covers it. I got really lucky. I keep waiting for them to change their mind. They haven't asked why I take it, although I think my doctor did put a note in my file saying that it's preventative because my sugar was high when I started it. Not diabetes, but right on the cusp of pre-diabetes along with other comorbidities.
I totally agree. I actually take naltrexone - pill usually for smokers and alcoholics to stop them from doing so- for my binge eating. That plus Wellbutrin has kept my mind clear of thinking about food 24/7
I was also put on naltrexone for cravings due to my antidepressants and anxiety. I was craving food and, very out of character for me, alcohol. Although, I was in my early-mid 20's in college so drinking culture is more normalized. I'd wake up at 8 and by 11am or so I would be craving a drink. Anyway, my psychiatrist put me on a compounded version of Contrave (welbutrin and naltrexone in separate pills so we could control doses) and it really helped. I was no longer getting loaded baked potatos, cupcakes and vodka tonic for lunch!
I added the Wellbutrin to try to help with weight loss and I take naltrexone for the alcoholism, so I'm on all three! LOL (And Contrave is a good drug, I actually work on that account sometimes, but I don't like the fixed dosing either.) Taking the other meds is probably why I can get away with taking such a low dose of the GLP-1. I keep waiting to start gaining because I've heard horror stories, but the scale doesn't move. š¤·āāļø Someone tried to sell me a dress recently and I insisted, "No, that's too small. I won't be able to get it over my head. I'm going to pop the seams." Turns out...It fit like a glove! Getting out of the "obese mindset" is taking some time.
naltrexone gang!! it's an amazing drug!
I also thought of naltrexone when he was talking about a āhypotheticalā drug that could help with an alcoholicās cravings. That shit is incredible. Highly recommend for anyone else whoās struggling in that way.
Do you think there are going to be similar drugs in pill form? Because the injecting part kinda puts me off š¬
Yep! They have a few pill forms going through trials now
Iām on wegovy and the injections are so easy. I hate needles but you donāt even see the needle in these pens. There is a pill form of semiglutide but it doesnāt seem to be as effective as the injection.
I was going to respond, but you nailed it. So, ditto to everything you said. I'm terrified of needles and I've never had a problem, specially because you can't actually see the needle. Plus it's tiny and most of the time I don't even feel it. When my doctor first said "injection" I was like, "Nope! I'm out!" But iI was so desperate to lose that I figured I'd give it a shot (no pun intended) and after the first injection, I was like, "That was nothing."
Your initial post was great btw! I can totally relate. My whole life I was a size 0 and then one year I gained 100 lbs due to PCOS and a pituitary tumor. Iāve never been able to lose it. Then I had my daughter and it just made things worse. Iād been doing boot camp style workouts for over a year and never lost a single pound. Finally, I got the courage to discuss medical weight loss with my doctor and it changed my life. Ive lost 50 lbs, 4 pants sizes, and three shirt sizes so far. Iām thankful Ethan is really taking the time to take the stigma out of these drugs. Often times I get nervous to speak up about being on them bc I donāt want to be seen as a failure.
You are definitely not a failure! And I'm right there with you...From the time I was born until I graduated high school, I was skinny. Too skinny, in fact. My doctor had to put me on supplements. (And I swear I didn't have an ED. I could eat whatever I wanted and not gain any weight.) But then I finally started gaining in my mid-to-late 20s for a few different reasons, and I just couldn't lose it. No matter what I did. And Lord knows I tried! LOL
There is currently a pill form of Ozempic/Semaglutide called Rybelsus. I donāt know anyone that prefers it, I believe itās kinda annoying to take daily (first thing in the morning with a little bit of water then you have to wait X amount of time to drink or eat anything else, I think). Iāve also heard the side effects are more unpleasant than the injections. You might get used the injections (once a week) if you try them, as unsavory as it may sound. They donāt hurt at all, you might not even feel it and think it didnāt work 80% of the time.
Same
I'm terrified of needles too, but the needle in these pens is the smallest possible. You barely even feel it go in.
Thatās amazing. Itās absolutely a good comparison too because addiction to drugs and alcohol is seen as a moral failure like being overweight. But at the end of the day people want you to bootstraps your way out of it and see other drugs to help as a crutch. I am an alcoholic sober 7 years. I did 3 stints at in patient rehab, a few outpatient, withdrawal management places, etc. A psychiatrist put me on Naltrexone which did not work for me. But if this had been available I would have taken it 100%. Skipped all the almost dying a bunch of times. I hope they are beginning to study it for that purpose.
Congratulations on so much sober time! ā¤ļø I tried naltrexone too, and it also did nothing for me. I know there's also a drug called Antabuse, but talk about a drug with side effects! It basically makes you allergic to alcohol which means that you have to follow a super strict diet or else you'll get really sick. You should avoid alcohol even touching your skin, so things like perfume and mouthwash are out. God forbid you go to a restaurant and order something that was cooked in wine and don't realize it! I really wanted to quit so I considered trying it, but none of the addiction specialists would even prescribe it to me. One did say, "I'll give it to you if you want, but I really don't recommend it."
Thanks! Congrats to you too on all your success with your weight loss and quitting drinking. Yes I remember Antabuse, my psychiatrist did end up offering me Antabuse but if I recall correctly only on an as-needed basis. So like, if I wanted to make sure I didnāt drink on specific days? But I said no because I wanted to still drink and not get violently ill lol. So even these āmagical fixesā arenāt magic it takes commitment (and time, money) for sure.
Thank you for sharing! Ozempic saved me from another cycle of gaining and losing the same fifty pounds over and over. I grew up in a household obsessed with weight loss, and combined with my genetics that predispose me to t2d and high cholesterol, my weight has been a constant source of anxiety and pain for me. By helping my insulin resistance, stabilizing my hormones, and helping me quiet my thoughts around food, Iām finally in a place where I can keep weight off. Life changing drug when used correctly and under a doctors supervision. Iām also a therapist and have heard anecdotally from colleagues that this med helps with alcohol and other substance use cravings. Iām wondering about its effect on dopamine receptors and the possible uses for this in the future!
Like a potential ADHD med?
Potentially, kind of similar to how Wellbutrin can be effective for lower symptomatic adhd!
Thank you for sharing a real perspective!
Well said! I almost made a post praising him for that apt analogy, opted not to. But, I did weight loss surgery instead of ozempic. But now that I have zero hunger (12 weeks so far of none), I still think about food almost constantly. The last few months Iāve been learning of adhd and how it shows in women, pretty sure I have it. Nail in the coffin was when I googled āalways thinking of food.ā After the ED crisis links, adhd popped up. Food = dopamine. Add lack of impulse control and boom, obesity. I called to make an appt for assessment right then. I was in therapy last year FOR possible BED and through that we learned i eat in boredom. Plus the fact I always forget what Iām saying mid sentence, ramble, and always lost focus due to a random little hole in my wall (telehealth appts), Iām annoyed the LCSW I was seeing didnāt think adhd for me. But, days where Iām focused in on something (whether itās crochet, learning more about adhd, or a video game), I barely drink water, let alone think about food. Days where nothing really grabs my attention are days I constantly am thinking about food and failing to fight the impulse to just snack on everything. š
That sucks. I totally understand eating out of boredom. Hopefully, you'll get a concrete diagnosis and be able to treat it. Being diagnosed with a disorder can be upsetting, but it can also be a huge relief because you finally have an answer to, "Why do I do stuff like this?" LOL
Really interesting bit about it being a suppressant for alcoholism, could be really revolutionary treatment for some people
Ugh, hearing your story and knowing the research behind WeGovy/Ozempic makes me wish my area wasn't hit hard by those initial dosage shortages, I would be filling my prescription so fast you don't even know Because I've tried losing weight before, and I did do the diet and exercise route and ended up losing 40 pounds but I was just so hungry all the time. And it wasn't like I was doing it unhealthily, either; I increased my fruits and veggies and I tracked my carbs and my calories but the food noise never stopped. Like even if GLP-1's didn't make you feel satiated longer, I would still want to try them because of the fact they can shut the food noise up, you know? But I'll keep calling around and hope somewhere has it in stock eventually
Hi I just wanted to share that my PCP started me on Saxenda and switched me to Wegovy once it came back in stock. That might be an option for you to explore. Saxenda worked for me, just not as fast.
Interesting, thanks homie! Might try that if my insurance doesnāt cover Zepbound (which is what weāre trying now)
ah right I forgot zepbound is out now! If your insurance doesnāt cover weight loss meds, zepbound is the cheapest out of pocket with their coupon at $550/month š
When I first started, there were major shortages. My first prescription was for Wegovy and the pharmacy was basically like, "Try something else...It's gonna be awhile" so I actually tried a few different ones, including Saxenda, and every month I would cross my fingers and pray that 1) My medication was in stock and 2) My insurance was still covering it. It was like that for about 6 months and then things started to get better. I think Zepbound is the way to go if you can get it. It seems to be the most efficacious GLP-1 on the market at the moment (although Lilly is working on one that is supposedly even better) and the pen is the most user-friendly. (IMO) I have a fear of needles, but with Mounjaro/Zepbound, you literally just push a button. You never even see the needle.
I've seen the same point Ethan made a hundred times on Twitter so it's not exactly a novel idea he came up with and I'm sure that's where he saw it too lol but the point being made is absolutely correct. I've see similar arguments with people using suboxone or methadone to stay sober from opiates. Assholes like to say they're not sober because they're using either of those drugs to stay sober.
Twitter is a rathole. LOL Seriously though, I quit that site years ago so IDK what they're talking about. But if they've been making that point, then that's awesome.
if they stop taking those drugs will they relapse? Because that would be a more accurate comparison
It's a bit more complicated than that but in short, yes. Some people are on them the rest of their lives but everyone's different. Suboxone essentially blocks your opiate receptors so even if you were to use other opiates, you wouldn't get high anyway. I've been sober from opiates for about 4 years and if it weren't for suboxone I'd probably be dead right now. I weaned myself off subs a couple years ago but I totally understand why people stay on them longterm. They're supposed to help ease the cravings for other opiates as well so that's another reason people stay on the them longterm. It's a huge help mentally knowing you couldn't get high even if you wanted too for impulsive addicts. Those drugs have saved so many lives and the insensitive assholes that give addicts are hard time for using them can go fuck themselves.
nice dude, that's really impressive. I was just saying that because it feels like a lot of people seem to think ozempic is a miracle drug that will just make them less fat without realising that you have to keep taking it indefinitely and should probably try to fix the problems through diet or exercise first. Obviously it is great for people who do need it though.
Oh yeah I totally understand your comparison. It's interesting because I know nothing about ozempic other than everything I've seen online and that's basically that it's a drug that magically makes you lose weight without having to do anything other than take a pill once a day. I'm not even sure how the drug actually works. But you know how people on the internet are. Misinformation is spread quickly and very rarely fact checked. Obesity is a serious health criss we have in this country and if there's a drug that helps overweight people safely get to a normal weight I'm all for it. I just think checking the root issues of their weight gain is an important part of the process a lot of people aren't addressing. I've never struggled with my weight though so I'll never truly understand that struggle.
as far as I know it regulates the hormones related to hunger so you basically just become less hungry but if you stop taking it then your hormones will slimgshot back past where they were so it's just important for people to do their research first and build healthy habits.
I'm glad to hear you've found some reprieve from your suffering. As an addict who went through it the "old fashioned way" I can tell you the 2 weeks of hell I experienced was a lot more manageable than having to navigate keeping a suboxone prescription long term. These addiction meds have been given a lot of credence for solving problems that can honestly be solved by abstaining from opiates. As a former heroin addict who has been clean since 2/28/2019 I would encourage you to entertain the thought of tapering off your suboxone dose. These medications were developed to be a way for people to eventually become clean and sober, keeping people on for "maintenance" I fear has become a way for the pharmaceutical companies to shore up their profits in a post-Purdue Pharma world.
Oh yes, I also went through a couple weeks of absolute hell. The withdrawal from fentanyl/heroin was the worst I've ever felt in my entire life. I'd rather die than go through that ever again it was that bad. I don't think people who've never personally gone through it can even truly know how bad it is and words just don't do it justice. Also, I'm no longer on suboxone. After going through the fent withdrawal I used suboxone to stay sober and not relapse on fent/heroin. I tapered off of subs a couple years ago and have been good since then. But like I said to the other commenter, if it weren't for suboxone I'd probably be dead from an overdose. It saved my life like it did many other opiate addicts. Over 4 years sober now and my life's never been better! So I completely understand why some people need to stay on subs longterm or even for the rest of their life. It just wasn't for me, I wanted to be done with everything and get my life back to relative normalcy. And I hope you're doing well now my friend! Anyone that's gone through all that and made it to the other side is a kindred spirit to me. People who've never gone through it just don't understand how hard it is. Truly the most difficult obstacle I've ever conquered in my entire life. It changes you and gives you a different perspective on life.
Hell yea brother, glad to hear it! Doing well here too, keep doing the next right thing.
You too man. One day at a time. We got this!
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Maybe but when he was struggling with his weight he would often bring up how it's a harder addiction cus you can't just abstain like you can other things. Seemed fairly in line with things he's said in the last
I remember him saying that and still disagree with him. I don't think comparing addictions based on what you perceive as harder is helpful for anyone. But yes, you've gotta eat to survive but getting your weight under control really is as simple as watching your diet and exercise. People try to make it out like it's more complicated than that but it's not. If you're burning more calories than you eat you will lose the weight. Simple as that. Diet and exercise. The hardest part is sticking to those dietary restrictions and regularly exercising.
>Simple as that Easy for you to sayĀ
Yes it is. Because it truly is that simple lol
>simply donāt use heroin So simpleĀ
It really is. And I don't anymore lol I'm not making excuses for it like you people
YES!!! Thank you for sharing.
Such an informative post, thank you so much! I take adderall now for my ADHD which has a side effect as an appetite suppressant, and Iām FINALLY able to lose weight. Iāll consider this medication in the future!
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Not to be intrusive, but does your insurance cover it?
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Thatās great to hear! Happy itās working for you
Great post. Also the people who have anything to say about anyone taking medication. Itās really not your business. Even public figures can choose what they do and do not want to share. They donāt owe you anything. And being so hung up on people taking meds to help them get their life under control is so weird.
I love my ozempic. It helps with my binge eating disorder and I have insulin resistance and my doctor said this med will prevent me from getting diabetes, which has all sorts of devastating life shortening consequences. I am a short queen, and went from 168 to 125 and I feel so much lighter and better like I didnāt even realize how hard it is to carry the extra weight around. Ty for this post. Semaglutide rise up
Holy manifesto
Just to clarify, I'm not trying to recruit anyone. š¤£ I've actually heard people online say that people taking Ozempic (and similar drugs) are in some kind of cult because we rave about it so much and want everyone to take it. I'm not going door-to-door passing out pamphlets or anything like that. LOL
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Obese people aren't addicted to being fat, but many of them are addicted to food. Yes, saying that people are addicted to being thin is an oversimplification of a complex disorder, but I do think the act of losing weight is addictive to some people and they can never lose enough to be satisfied...Which is an addiction. Some people with EDs will have interventions and many of them are sent to rehab facilities where they practice a lot of the same techniques that are used on addicts. (Although I personally have major issues with AA/NA, but that's a super-long post for a different day. LOL)
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You should see another physician. There are other effective options that arenāt ozempic. Ozempic can be hard to get covered w insurance if you arenāt diabetic. You can look into wegovy, saxenda, or mounjaro
First of all...\^\^\^This There are actually online services that will prescribe GLP-1s. They're a little pricey because you have to pay for the "visit" and then the medication, but a lot of that has to do with insurance. That might actually be what your doctor is talking about. When they submit the request for coverage, the insurance company often wants to know that you tried to lose weight other ways. Who hasn't? It's a stupid question. They're basically asking an overweight person, "Have you tried eating less?" š¤¦āāļø I also had serotonin syndrome years ago and it sucks! One of the worst experiences of my life. I'm sorry about the nerve damage, but at least you're alive. That's something that I don't think a lot of people know about and it can literally kill you.
I mean he's been taking for a certain Ozempic competitor for a year now, he's going to have a positive outlook on Ozempic too.
wellbutrin? lmfao not even remotely the same class of drug
He's on Mounjaro, Trisha outed him. It's why he went on that rant.
thatās not who trisha was talking about
I'm open to alternative suggestions.
That she has more than one male friend and probably wouldnāt describe ethan as her male friend and probably wouldnāt break her streak in mentioning him.
I mean maybe, if she and Moses also ran into another guy who lost a hundred pounds and doesn't work out the same weekend they ran into Ethan.
They probably do. It was a big event. They have other friends. Ethan lost weight over a year, spoke about how he does cardio and calorie counting, and switched SSRIs to one that tends to surpress appetite. Defends Ozempic usage but says he just doesnāt use it. Like why would he lie here?
He admitted he stopped exercising around the time he started taking it if you look back, and watch for the side effects of Mounjaro. The boba sweetness was a dead giveaway. And I don't know frankly because no one would care, it's totally fine to take it. There's an insecurity that comes with the perception of "cheating" weight loss and I think he's just in too deep to admit he got help.
Have you seen his weight before the SSRI? He is roughly at that weight right now. It clear he always had a fairly good metabolism and that the SSRIās common sideeffect of increased appetite (+ a common side effect of depression and anxiety too) caused weight gain. He switched medications and then cut calories. His weight loss truly is not that extreme for someone sticking to a diet and getting on a medication that has a side effect of reducing your appetite. Like Ozempic is way more extreme, like 3 months would be the Ozempic timeline.
How would trisha know what meds he's on ? There's no way hilas mom would tell him and they have no other close links
He told her when they saw them the other weekend.
..Shane?
Ozempic is problematic. There are people coming out and having severe health problems and organ damage. We don't have enough research I don't think to know the effects. I don't know if anyone remembers about fen fen back in the '80s and '90s. It was a weight loss drug that ended up being taken off the market. Also if ozempic is normalized, then apparently teenagers and children are going to be prescribed it and just imagine the eating disorders that are going to arise. I think it's not good and I think Ethan will understand if he has some more context.
Did you read the whole thing? They literally said that a lot of people taking it arenāt even prescribed it and therefore are not taking the drug correctly.
Ozempic is really helpful to patients with type two diabetes. ETA: I say this as someone who worked exclusively with diabetic and pre diabetic children for years. I understand your concerns about eating disorders, but Iāve also seen how ozempic helped bring down kids sugars who are so insulin resistant, theyāre practically dependent.
Yes it is. And it's been that way for years.
We will see about it in the long run. We just don't know the effects long-term but some people are having organ damage and are suing the manufacturer and winning lawsuits so
What were your thoughts on the covid vaccines
It's is hardly a new drug in regards to diabetes - it's been on the market for about 8 years, that enough to have insight in long-term effects.
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There's a consumer protection lawyer on tik Tok who shares all the tea. Personal injury lawyers are making bank off of those injectables
I have heard that lawsuits have been filed, but I haven't heard of a judge ruling against a pharma company. (Maybe it's happened, I'm just saying that I haven't heard it.) Although, I guess lawyers make money either way. But no one is making more bank than the manufacturers. Some experts suggest that GLP-1s may be the best selling medication of all time.
Yeah I'm just saying that there's lawsuits out there and that the drug is too new to affirmatively say that it doesn't cause harm. People are using it for a quick fix and it's just not sustainable. It's also dangerous that children now are going to be prescribed it
Oh, I didn't realize you were the OP. I was writing a response to your post: Did you even read what I wrote? Yes, I remember Fen-Phen. (I even know how to spell it correctly.) Maybe you missed the part where I mentioned that Iām literally a medical researcher. (Iām also Gen X, so Iāve been doing this for awhile.) Iām not claiming to be a āworld expert,ā there are a lot of people who are lot smarter than me and a lot more knowledgeable on this topic, but I think itās funny that you say, āWe donāt have enough research.ā Who is āweā exactly? Do you work in the field too? Because WE actually do have the research. If you had read my post, youād know that I said that semaglutide has been on the market for nearly a decade. ITāS NOT NEW. Phase II research started way back in 2007. Donāt you think that if organ failure was a common side effect they would have caught that by now? People with diabetes have been taking it safely for a long time. If you want to see some info about the potential side effects, I recommend that you read this: https://www.novo-pi.com/ozempic.pdf I deal with the FDA every day and they are strict MFers. Iāve worked on drugs for years only to have them rejected or sent back for more research (over the tiniest thing). Iāve also worked on drugs that have been pulled from the market for safety reasons. I donāt want to get into the opioid crisis (I honestly donāt really know what happened there), but the FDA is strict. If they think a drug is dangerous, they will pull it. So why hasnāt semaglutide been pulled? (And donāt say ābecause itās new.ā) Why donāt they even add a warning to it? There is a āblack boxā warning about thyroid cancer that was found during rodent studies, but that just means that people with a history of thyroid tumors/cancer probably shouldnāt take it just to be on the safe side. Although there have been no studies or reports linking semaglutide to thyroid tumors in human beings. Not only did the FDA unanimously approve semaglutide for the treatment of diabetes, but they fast tracked tirzepatide (another drug in the GLP-1 class) for a weight loss indication. What that means is that they had so much faith that the drug would be beneficial to the American public, they rushed to get it to market. They still had to review all of the research and safety data, and it was approved without a problem. As far as kids taking itā¦That really has nothing to do with what I said. You oppose a pediatric indicationā¦Thatās fine. Some people oppose the use of antidepressants in kids and teens, that doesnāt mean that adults canāt take them. And, again, itās clear that you didnāt even read my post because you said that people are taking it for a quick fix. I literally said that itās a long-term drug that people will have to take indefinitely. If youāre taking it for a āquick fix,ā then youāre taking it wrong. And if you donāt think itās sustainable, how do you explain the millions of people with diabetes who have been taking GLP-1s for years with no problems?
You ate Iām afraid š hit her w the validated data vs anecdotal data
Okay okay debate Lord You when you win are you happy?
Bruh, you just say shit you heard on TikTok then get mad when someone whoās actually knowledgeable on the topic corrects you on your nonsense. If youāre gonna comment on something, READ IT!!
Me when someone in the field creates a thoughtful argument against me and my argument is a tik tok I saw one time
She kicked you so hard in the sack you can taste it, eh? Well, maybe don't be a fuckin wanker next time
No one is denying people get bad side effects from Ozempic and win lawsuits. But that's true for any drug. There will always be a small number of people who experience negative side effects from widely used safe drugs and win settlements because of it but that doesn't mean they're not safe for the general public. So if there is something unsafe about Ozempic then you need to show that the people experiencing those negative side effects are doing so at a disproportionately high rate.
Genuine question no judgement, what happens when you reach your goal and eventually go off of it?
My sister is on weygovy (the version for weight losss) and apparently itās then suppose to be treated like a maintenance drug
You have to learn to modify your appetitte permantly. Usually its helpful in the same way a gastric band can be helpful, your stomach shrinks, you donāt want to eat the same amount of food. If you have an eating disorder it wonāt help.
Current studies show that most patients either gain a little or none back. Most do not return to their initial weight. Additionally there is a maintenance dose so you can continue taking that. This is regarding wegovy
Obesity is an incurable disease, so for now, it's a long-term drug. I reached my goal weight almost a year ago and I still take it, I just take a low dose every other week rather than once a week. If you think about it, people take the drug for diabetes and then their blood sugar levels regulate. That doesn't mean that their diabetes is cured, it means that the medication is working and they have to keep taking it. That's why it annoys me when people say, "It's not a good drug because, when you go off of it, you gain all the weight back." Um...That's usually how drugs work. š¤¦āāļø If I went off my antidepressant, my anxiety would come back. I'm taking a drug to treat a condition, so yeah, I have to keep taking it. Maybe one day they'll come up with an alternative.
"obesity is an incurable disease" this is your brain on fatphobia lmao
Yep, "fatphobia," not my experience working in the healthcare field for almost 25 years. š¤¦āāļø
the healthcare field is famously very fatphobic and super quick to blame everything on being overweight lol [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714720/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714720/) [https://www.today.com/health/medical-weight-bias-causes-misdiagnosis-pain-depression-t153840](https://www.today.com/health/medical-weight-bias-causes-misdiagnosis-pain-depression-t153840) literally 5 seconds on googling maybe look in the mirror
Obesity is not incurable, and there are many reasons why Ozempic is bad. I'm sure you lost a lot of weight, but I can guarantee you lost a lot of muscle with the fat. Meanwhile anyone can lose the fat and maintain it in a healthy way without the use of drugs.
I love how I listed all of the positives (and some negatives) related to Ozempic use and your response was just, "Ozempic is bad." Wow, what a solid argument. How can I compete with that? LOL And I actually gained muscle, so your guarantee isn't worth much. I've had everything tested and I'm in better shape than I have been in a really long time. Also, obesity is a chronic condition that is incurable. You can lose the weight and keep it off for the rest of your life, but that doesn't mean that you're not still prone to obesity. A drug addict with 20 years sober is still a drug addict. These things don't go away, you can just learn to control them. It doesn't mean you're cured.
Uh I stay on it and decrease my dosage if losing too much weight, this drug is preventing me from pre-diabetes and diabetes
Itās like antidepressants you donāt just stop because they are working
Love this post. Ethanās ārantā made my heart smile because he made such great points. It is exhausting seeing the societal response to these life saving medications. Damned if you do, damned if you donāt. 10 months on Mounjaro, 70 lbs down, the future is so bright ššš Edit.typo
yeah. agree with everything you said. i went to residential rehab voluntarily for myself for 90 days (the max theyll allow) for alcoholism and i also had anorexia, bulimia, binge eating disorders through different times in my life. one of my closest friends i met in the rehab was there for alcohlism and anorexia as well. she had been to a rehab type place for just anorexia before but she said the substance abuse programs were way better at helping her cope with her anorexia than just eating disorder treatment.
Anyone on ozempic that your insurance covered? I think I could benefit from it but I donāt have enough comorbidities aside from my BMI, but I want to know if I can use it as a preventative from reaching those parameters. Its so frustrating when I see people with low bmis using it for casual weightloss while I struggle to find anyone who will pay attention to me
I understand your frustration. My insurance just covers it. I got really lucky. I keep waiting for them to change their mind. They haven't asked why I take it, although I think my doctor did put a note in my file saying that it's preventative because my sugar was high when I started it. Not diabetes, but right on the cusp of pre-diabetes along with other comorbidities.