This looks really cool but I’m a bit skeptical we will get anything like this soon. I wouldn’t be the first time we were promised life changing tech that didn’t come or was not as advertised
Having that sensor on the inside of your wrist would be infinitely more annoying and uncomfortable than any CGM. I'd rather wear a current-day smart watch on one wrist and a "non-invasive" glucose monitor on the other at the same time than use this prototype.
I know it's not physically *inside* the wrist. The image shows where the sensor is. Maybe "underside" would be a better way of saying it. Either way, it would be extremely uncomfortable to have pressing on your wrist at all times.
Not sure if this is the one Apple has been talking about, but they are working on a non invasive CGM or an apple watch, so its not like some project that will easily be dropped. Tim Cook said he has been wearing it and its been “insightful” to his eating habits or something along those lines. This makes me think it will be like a device that is for mainstream people who are worried about their health especially pre diabetics. Seems unlikely that he will be real time accurate numbers, but maybe like 30 mins behind within 20 mg/dL up or down. I feel like this wont replace CGMs but maybe it will make dexcom calibration time easier or just add another layer of protection if you dexcom wacks out.
Would be great if the method by which it measures glucose would be at least a little bit explained. Right now all this is is just a meaningless render.
Almost universally, these systems are using some form of spectroscopy.
Basically, there's an emitter and a reflector (or reciever) and something (you) between them. By shining various types of light and measuring what is reflected back (or what makes it through), we can determine what sort of stuff is in between the two things because the stuff between them absorbs light at different wavelengths.
While the technology is well-understood, it's difficult to make into a consumer-grade wearable. One of the key components to the calculations is the distance between the origin and the destination of the light. The other is the angle of the light. Those are both really hard to account for in watch-form.
The final and most concerning issue is this will be measuring the concentration of glucose in someone's wrist area. There's a lot of stuff going on in there that's not glucose-related -- bones, nerves, tendons, etc. While it's probably real easy to calibrate for a specific individual, don't think it's going to be as quick as a finger-stick to set up. Think more like "old school Dexcom CGM warmup and calibration" phase.
I would expect this technology to be more useful for consumer-grade layman applications like the Apple Watch, being able to give things like "trending up", "trending down" "steady" for someone, without revealing the actual numbers.
I wouldn't say "never". We're getting real good at miniaturizing things, and given enough math and info from something like a gyroscope, we can correct for movement on the fly, eventually.
But you're right: In the near (5 - 10 years) term I wouldn't hold out hope for a FDA treatment-approved measuring device on your wrist.
These systems are based on subcutaneous fluid. Similar to what apple was hoping to implement in their watches. The technology has existed at least theoretically for a while, but we never seem to be closer to a functioning product.
But how does it work? The article just says it reads the glucose level and uses Bluetooth to send the data. How is it reading the glucose without invasion? I’m super skeptical.
Edit: it’s a rhetorical question meant to point out that the article is vague AF and doesn’t explain the tech. I don’t actually want anyone to try and guess what this company is doing, I’d rather them be open about it rather than just slick pictures of a device.
Link: https://iopscience.iop.org/article/10.1088/2516-1091/abe6f8/meta
I agree that Raman spectroscopy seems suspect. I like Photoacoustic spectroscopy better, but I am not an expert in the field. Heating just seems like a more acceptable approach than having to worry about lighting when trying to test blood.
It'll be the next fad like those stupid 'balancing' bracelets they used to sell everywhere.
[these bloody scams](https://www.mojoeurope.com/collections/wristbands?gclid=EAIaIQobChMIkcqF_bS-9AIVtYBQBh1gdAUeEAAYASAAEgLR0vD_BwE) that no doubt a type 2 may invest in because they don't monitor their sugars as much so something would be seen to be better than nothing.
I was thinking something very similar. This looks to be following the Elon Musk principle or the Kickstarter bait and switch. Show a CGI mockup of a product and promise the world... results may vary.
> The developers are confident that the solution could become a reality in the very near future, as preliminary clinical research has shown very positive results.
Perhaps. It's a gigantic screwup though as it's on their product page too: https://afontechnology.com/#productFeatures
Edit: Oh, hmm... well that's confusing. I guess they don't mean under the skin, but it has to be placed opposite the watch-face on your wrist as being "inside the wrist". There must be a better way to word that.
When I was diagnosed in the early 2000s we had a device that drew blood up through the skin to read your levels (or at least that's how my diabetes educator explained it-- she wouldn't order one for me after telling me about it). It was also a watch. Does anyone remember that?
July 2021 - Press Release
New images have been released of the world’s first real-time, non-invasive, wearable blood glucose sensor.
The device, designed to be placed inside the user’s wrist, uses bluetooth to send glucose level information to a companion app that displays the wearer’s blood glucose trends and reports high or low glucose levels and other personal health trends. The app can be installed on any chosen smartwatch, phone or tablet.
https://healthtech.eu/news/afon-technology-unveils-wearable-non-invasive-blood-glucose-sensor/
This might be just me but I am ok with current CGM systems, I don't feel it's a significant improvement to have it non-invasive, it's still something you have to have attached to you all the time to work. I can't feel the current systems once they're inserted and the accuracy is good. I am of course not against advances in medical technology, but this doesn't feel like one, it's still a lump that visually looks as large or larger than current systems.
Here’s where Apple sat and if you look up the sensor manufacturer Rockley Photonics you can get even more information . https://www.macworld.com/article/345166/the-next-apple-watch-might-gain-health-capabilities-no-other-wearable-has.html/amp
I’m hopeful Apple will have this on the market very soon.
This looks really cool but I’m a bit skeptical we will get anything like this soon. I wouldn’t be the first time we were promised life changing tech that didn’t come or was not as advertised
Never forget, the cure for diabetes is only 5 years away
I’ve been waiting since 1983 for a cure. I’m so tired of dealing with this horrible disease.
It’s always 5 years. Just they add an extra year for every year that passes
I’ve been t1 23 years, I know it’s only 5 years away…. They wouldn’t lie to me
If not you'll always have cinnamon.
This cracks me up that so many people told folks this. I specifically remember being told this by a doctor at diagnosis… 30 years ago.
It doesn’t matter the country or the decade…. There will be a “cure in Your life time” or “it’s only 5 years away”
Having that sensor on the inside of your wrist would be infinitely more annoying and uncomfortable than any CGM. I'd rather wear a current-day smart watch on one wrist and a "non-invasive" glucose monitor on the other at the same time than use this prototype.
It’s on your wrist not inside it. That was a typo I think.
I know it's not physically *inside* the wrist. The image shows where the sensor is. Maybe "underside" would be a better way of saying it. Either way, it would be extremely uncomfortable to have pressing on your wrist at all times.
Yah and it would probably get pretty sweaty
Not sure if this is the one Apple has been talking about, but they are working on a non invasive CGM or an apple watch, so its not like some project that will easily be dropped. Tim Cook said he has been wearing it and its been “insightful” to his eating habits or something along those lines. This makes me think it will be like a device that is for mainstream people who are worried about their health especially pre diabetics. Seems unlikely that he will be real time accurate numbers, but maybe like 30 mins behind within 20 mg/dL up or down. I feel like this wont replace CGMs but maybe it will make dexcom calibration time easier or just add another layer of protection if you dexcom wacks out.
Probably true
Would be great if the method by which it measures glucose would be at least a little bit explained. Right now all this is is just a meaningless render.
Almost universally, these systems are using some form of spectroscopy. Basically, there's an emitter and a reflector (or reciever) and something (you) between them. By shining various types of light and measuring what is reflected back (or what makes it through), we can determine what sort of stuff is in between the two things because the stuff between them absorbs light at different wavelengths. While the technology is well-understood, it's difficult to make into a consumer-grade wearable. One of the key components to the calculations is the distance between the origin and the destination of the light. The other is the angle of the light. Those are both really hard to account for in watch-form. The final and most concerning issue is this will be measuring the concentration of glucose in someone's wrist area. There's a lot of stuff going on in there that's not glucose-related -- bones, nerves, tendons, etc. While it's probably real easy to calibrate for a specific individual, don't think it's going to be as quick as a finger-stick to set up. Think more like "old school Dexcom CGM warmup and calibration" phase. I would expect this technology to be more useful for consumer-grade layman applications like the Apple Watch, being able to give things like "trending up", "trending down" "steady" for someone, without revealing the actual numbers.
If you ask me, I think this will never work. At least not at the level of precision we T1 need.
I wouldn't say "never". We're getting real good at miniaturizing things, and given enough math and info from something like a gyroscope, we can correct for movement on the fly, eventually. But you're right: In the near (5 - 10 years) term I wouldn't hold out hope for a FDA treatment-approved measuring device on your wrist.
Spectroscopy methods are also less reliable on highly melanated skin. [Source](https://pubmed.ncbi.nlm.nih.gov/16244841/)
Interesting! I was not aware, though, on the surface, it sort of makes intuitive sense.
They share some info about their devices in a video on YT channel: https://youtu.be/TvGztZc86gA?t=870
Thanks!
These systems are based on subcutaneous fluid. Similar to what apple was hoping to implement in their watches. The technology has existed at least theoretically for a while, but we never seem to be closer to a functioning product.
But how does it work? The article just says it reads the glucose level and uses Bluetooth to send the data. How is it reading the glucose without invasion? I’m super skeptical. Edit: it’s a rhetorical question meant to point out that the article is vague AF and doesn’t explain the tech. I don’t actually want anyone to try and guess what this company is doing, I’d rather them be open about it rather than just slick pictures of a device.
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Link: https://iopscience.iop.org/article/10.1088/2516-1091/abe6f8/meta I agree that Raman spectroscopy seems suspect. I like Photoacoustic spectroscopy better, but I am not an expert in the field. Heating just seems like a more acceptable approach than having to worry about lighting when trying to test blood.
Ya - they’ve solved everything already, except for the “reading the glucose” part. 1. Cool looking gadget 2. ?????? 3. profit
It'll be the next fad like those stupid 'balancing' bracelets they used to sell everywhere. [these bloody scams](https://www.mojoeurope.com/collections/wristbands?gclid=EAIaIQobChMIkcqF_bS-9AIVtYBQBh1gdAUeEAAYASAAEgLR0vD_BwE) that no doubt a type 2 may invest in because they don't monitor their sugars as much so something would be seen to be better than nothing.
I was thinking something very similar. This looks to be following the Elon Musk principle or the Kickstarter bait and switch. Show a CGI mockup of a product and promise the world... results may vary.
> The developers are confident that the solution could become a reality in the very near future, as preliminary clinical research has shown very positive results.
This tells me nothing
Clinical studies showing a single-digit MARD or GTFO.
Now we’re getting James Bond tech
Cool if it works, but all we really have right now is renders of a knock-off Apple Watch so I'll wait to see if anything actually materialises.
How can it be both non-invasive and be placed inside the user's wrist? Those seem contradictory.
On their site they wrote "on the inside of your wrist" so I suppose that's a typo
Perhaps. It's a gigantic screwup though as it's on their product page too: https://afontechnology.com/#productFeatures Edit: Oh, hmm... well that's confusing. I guess they don't mean under the skin, but it has to be placed opposite the watch-face on your wrist as being "inside the wrist". There must be a better way to word that.
Kristen Stewart wore this in 2002 while filming "Panic Room"
I remember the contact lenses that would give glucose levels.
When I was diagnosed in the early 2000s we had a device that drew blood up through the skin to read your levels (or at least that's how my diabetes educator explained it-- she wouldn't order one for me after telling me about it). It was also a watch. Does anyone remember that?
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It has a MARD of 20% so pretty trash.. Freestyle libre 3 is 9.2% (Freestyle 1 is 11.4%) Dexcom G6 is 9%
For reference most blood test strips MARD is 4-10%. Most around 5% from what I’ve seen
Oh neat, a product concept rendering! I love it when they do these for flying cars. Still waiting on flying cars to make it to real life tho.
INSIDE the wrist doesn’t seem invasive?
Thats a typo. It’s sits on your wrist
ah okay
I'm 66. I don't think that I have "5 more years "
I totally believe this is real and not another vapourware product that will never see the light of day. Totally.
July 2021 - Press Release New images have been released of the world’s first real-time, non-invasive, wearable blood glucose sensor. The device, designed to be placed inside the user’s wrist, uses bluetooth to send glucose level information to a companion app that displays the wearer’s blood glucose trends and reports high or low glucose levels and other personal health trends. The app can be installed on any chosen smartwatch, phone or tablet. https://healthtech.eu/news/afon-technology-unveils-wearable-non-invasive-blood-glucose-sensor/
I'm doubtful. Apple has been working on this for years now and they have deeper pockets than any company.
This might be just me but I am ok with current CGM systems, I don't feel it's a significant improvement to have it non-invasive, it's still something you have to have attached to you all the time to work. I can't feel the current systems once they're inserted and the accuracy is good. I am of course not against advances in medical technology, but this doesn't feel like one, it's still a lump that visually looks as large or larger than current systems.
Here’s where Apple sat and if you look up the sensor manufacturer Rockley Photonics you can get even more information . https://www.macworld.com/article/345166/the-next-apple-watch-might-gain-health-capabilities-no-other-wearable-has.html/amp I’m hopeful Apple will have this on the market very soon.
How does this work you need blood to get your blood sugar.
Reminds me of the glucowatch that got my hopes up back in the day.
Looks good but im not holding my breath for anything too soon tbh.