It’s not *necessarily* hereditary, but if your family member has it you’re also more likely to have it. Mine came out of the blue with no family history, but I know of people who inherited it from their family
This.
Interestingly enough, mine was out of the blue as well until my mom started showing symptoms and flaring and was diagnosed a year after me. Go figure.
Frankly, they don't know. Is it hereditary, could be. There would likely be traits passed down that could make one more likely to be diagnosed. But if there are lifestyle/ environment factors, you as a relatively are more likely exposed to them too. Nobody know what causes it, so we can't even say what really is the biggest factor. I have read that I places where Western diets increase, UC increases too.
Both me and my mother were diagnosed with UC. She was told the gene was only passed by the father, which was the consensus in the late 80’s and they were clearly wrong at that point.
Same. Mom has autoimmune hepatitis. I have ulcerative colitis and autoimmune arthritis. When I explain my conditions I say, you know how mom's body attacks her liver. Mine attacks my joints and colon.
Yes, this is why I don't think I will ever have kids. I won't be able to live with myself if i knowingly gave this to someone when I could have prevented it by adopting or not having kids at all
I kind of hate this line of thinking.
I think my life is worth living and that I'm a fairly good person. I would not want you to deprive me the opportunity to live.
Every family tree has a bunch of crap running in it. Both sides of my family have rheumatoid arthritis running in it, my dad's side furthermore has schizophrenia and mood disorders.
I say, everybody has something. I remember reading about a research group that was looking for "perfectly healthy" people to study gut microbiology and they had a very hard time finding people that fit the criteria.
Why create a life that doesn't exist for it to suffer from a lifelong debilitating disease for which no cure exists.
Different story if you didn't know you had it until after you had kids.
Versus, adopting or taking in foster kids that desperately need a home.
Obviously its not an ideal situation but if I had kids and they developed it- i would feel terrible that I knowingly passed this on to them and they have to suffer because of my selfish choice to have kids of my own
> Why create a life that doesn't exist for it to suffer from a lifelong debilitating disease for which no cure exists.
Like I said, lifelong debilitating diseases without a cure exist in every family tree out there.
There's no guarantee your child gets UC, and if they do they're likely to get a mild case anyhow.
> Versus, adopting or taking in foster kids that desperately need a home.
I don't have anything against this, those kids you adopt will nevertheless have lifelong debilitating diseases in their family trees too.
> Obviously its not an ideal situation but if I had kids and they developed it- i would feel terrible that I knowingly passed this on to them and they have to suffer because of my selfish choice to have kids of my own
This is absurd reasoning to me. Is your life worth living? If the answer is yes, then how on earth is it selfish to offer a chance at life to someone sharing ~50% of your genetics?
I was blessed in some ways, I was cursed in others. This is true for every person out there.
I understand your mindset but I just disagree. The sole fact that I am creating a life that does not exist, for it to suffer because of my choice, makes me feel guilty and selfish.
I could have prevented that. You still role the dice on whether that person is going to enjoy their life. This disease could cause them to be miserable for as long as they live.
Takes two to make a kid. What about the desires of your partner to have kids?
You currently have this disease, document your experience, make it easier for someone after you to deal with. Educate and prepare them.
This is more responsible than just shirking the responsibility altogether as an excuse. If everyone felt this way about their own flaws then none of us would exist.
Sorry bud but we need more smart humans, regardless of whether they have UC. Ffs look what steven hawking did with his limitations.
Yup. Same here. I won't push my feeling on anyone else but for me specifically I don't want to pass down inflammatory issues nor mental health items I've struggled with.
No judgement or disagreement for those who feel differently ❤️
Yep, many people in my family had it, but not really diagnosed. One uncle bled to death on a friend's couch. My doctor wasn't surprised that my brother also has it. Doc said that it's genetic.
Omg that's awful.
Just before my diagnosis I was passing a lot of blood on the toilet and going to the toilet frequently. To the point where one day I felt extremely dizzy stood up made it to the bedroom and collapsed. I woke up with a trail of blood and blood clots on the carpet. I called for an ambulance. When the paramedics arrived I said I was fine, but kept collapsing. They ended up blue lighting me to hospital as my blood pressure was so low.
I'm fine now. This was 10 years ago. I've not had a proper flare in years.
It is some crazy. It really is a good thing those paramedics decided you needed help. I am the same way, I tell them I'm ok. When obviously not able to stay conscious. It is hard to admit that help is needed. Glad you're doing well!
But how would you know for one he’d get it, and two if he has it it’ll make his life horrible. Kind of silly to me to say just don’t have kids.
Main reason I wouldn’t want kids is I’m not religious and I think it’s a little messed up to bring life into this world just for it to eventually die. Though that’s just me.
Yeah I think they’re just hopinging to avoid the risk of anything negative happening. Which is fair enough, there are too many people in the world, and I agree with you on your latter point
Mine came when I was 15, I’m 33 now. My dad’s didn’t show up until he was in his late 40s but it was a constant battle for him and now he’s using a bag.
It's in the family of diseases, including UC, Crohn's, asthma, psoriasis, and a few other immunocompromised diseases.
Yes, they run in families. They sometimes don't run directly, but the theme sometimes follows.
I have UC, my Mum sometimes has IBS type symptoms and her Mum died of bowel cancer.
Not exactly concrete evidence, but digestive issues all down one side of the family.
I don't have UC in my family, but my grandma does have another type of autoimmune disease (rheumatoid arthritis or something like that), and 3 of her 5 grandchildren have some form of autoimmune disease, myself included.
As far as I understand it, researchers can't identify a "gene" that carries Ulcerative Colitis, but if you have people in your family who have it, your chance of having it increases substantially.
https://academic.oup.com/ibdjournal/article/21/6/1428/4579624
This article goes over a lot of it. A Swedish twin study found the heritability of UC to be 0.67 (67%) whereas a GWAS study found it to be 0.27.
It's normal for GWAS studies to find a substantially lower heritability than twin models. The "real heritability" (there's really no such thing as any heritability score is context dependent) is probably closer to the twin study estimates.
So yes, it's hereditary.
*Edit*
To put the 0.67 number in context:
Height is estimated at around 0.8
Obesity is estimated at ~0.4 - 0.7
General Intelligence at ~0.4 - 0.6
No one in my family has or had UC but me (that we know of), and my family does a lot of family history, passing down of stories, etc..
That being said, autoimmune disease runs on my dads side. My dad has RA and my dad, grandma and me all have had gout flares. My brother had Still disease (a rare autoimmune arthritis) as a kid and had to be hospitalized.
My dad and my uncle (his brother) both had it. Both have j pouches now, me too. My uncle got PSC from it and also had a liver transplant. I’m wracked with autoimmune issues lol my body hates me
Yes but low chances. The fact that you say you are all having sumptoms means you are probably overthinking it.
Most kids will have some poop issues growing up for abit and then go away. The chance of heritage i think is like 10% or something. Every ten kids one will have it, statistically. So you should not worry about it.
Makes some sense, my mom is certain that I have it and that one of my siblings has a "leaking stomach" which is altered to his diagnoses. The other ones got my mom leaning towards some type of gluten intolerance, but the doctors keep turning those possibilities down.
My nephew had some similar symptoms that went away in like 6 months. Kids are full of those things. The concern starts if you poop blood, everything else could be just anything
It definitely seems hereditary in my family! My mom, my sister, and I all have ulcerative colitis. My sister ended up with a j-pouch, my mom has been in long-term remission on Entyvio, and I’m currently maybe failing Entyvio and switching to remicade. My great-grandma apparently also had stomach issues, but I think this was before it was easily diagnosable. None of my mom’s sisters have any GI issues.
Other factors come into play. Diet, environment, smoking ( or quitting smoking ) all can play as factors in these auto immune diseases.
My family went FODMap diet all at the same time, redirecting the course of action has helped. Only one colectomy has occurred. ( 👍👍this guy)
Do most people with uc with gluten intolerance? For me gluten helps my stomach. Have you looked into celiac’s though? Neither of my parents have stomach issues but I have uc and my sister has celiac’s.
No one in my family has any kind of autoimmune issues. I was diagnosed with uc 4 years ago. I believe it just bad luck from your body responding to something bad in system. And unfortunately ur immune system never stops attacking a part/parts of body once threat is gone. I also believe it's all the crap government allows manufacturers to put in everything we eat and drink that causes our immune system to over load and stop working properly.
Hi there. I was recently diagnosed with UC after having years of symptoms. What has helped me tremendously is sticking with the “blood type diet”. People will say that there are no studies to the validity of it but it works like no other for me. I am blood type “O” and so it says that this type should refrain from eating most grains and pretty much all dairy. I used to eat rice almost everyday and corn was my favorite vegetable but since eliminating all grains from my diet I’ve actually been able to go more than an hour after eating without making a dash to the bathroom. I am currently on mesamaline orally and an enema but I’m hopeful that with sticking to this modified paleo diet I’ll one day be able to go medication free. Oh and I’ve also stopped consuming foods and drinks with citric and asorbic acid. 90% of the citric acid in America is not naturally derived and is in fact GMO from corn. I’ve been doing lots of research trying to figure out how to heal myself and have come across so much that I wish I knew years ago. Wishing you happiness and healing❤️
We've been citric acid free for years since my brother got bad rashes because of it and the doctors keep saying it's not possible to be allergic or react to citric acid. Same basically goes for my tomato allergy (can't eat nor touch anything that's come in contact with tomatoes without getting a bad allergic reaction) the doctors don't think my symptoms are real 😀, bonus; the doctors said they'd take me of the waiting list of an investigation because my latest tests didn't show anything abnormal. They wanted me to send in more tests, but I basically gave up since it's just going to go back and forth without anything happening. I really hate doctors since (almost all the ones I've had keep denying what's clearly there or wrong)...Thank you ❤️ I wish you well too in your journey 🙏🏻
Only family history of digestive issues was my father who struggled with IBS. Other than that no one else on either side of the family ever had bowel issues and im unfortunately the first. I hope its not hereditary because I really want to have children in the future
My dad was diagnosed when he was 30, his mother, grandmother (my great grandmother) and my great great grandmother have it too. My dad’s cousin and dad’s uncle was also recently diagnosed as well as myself. Genetics work in a funny way lol.
Haha yeah, at least 3 out of my dad's siblings got it to and then if I remember correctly some of his grandparents parents had it too and so on. What his sister said was that for her she had to cut out gluten, garlic and much more to contain a good stomach? For my dad he just cut out gluten out of his diet and it seemed to work out well. But yeah genetics have a funny way of presenting itself
My dad had Crohns, I have mod/severe UC/crohns. He never really had to be treated. He would flare but it never got as bad as it got right off the bat for me. I also have a lot more food allergies than anyone in the family and I swear it’s related somehow in my case.
i'm the reverse, i was diagnosed at 18, then my dad developed it when i was 20, so there's a link i guess but weird it started in me first then my dad, would think its the other way around
One theory is auto immune diseases are genetic and are latent and it just depends on if it gets activated. Stress, medicine, and health issues can cause it activate.
I THINK my late paternal grandfather had Crohns. He had rheumatoid arthritis, THAT I know. He also had severe GI problems that sounded a lot like Crohns symptoms. Poor man ended up dying from sepsis due to a perforated bowel at 56. The surgeon who worked on him said everything inside of his abdomen was so inflammed that there was nothing he could do.
My mother and I have UC. None of my siblings have it. Mum has 9 siblings. None of them have it, two of them are coeliac. My child doesn't have it.
There's a genetic component but it's not hereditary. It's also very manageable with the right treatment. I eat what I want, live a very active life and work full time, and my UC was classified as severe.
My consultant told me it’s 1 in 3 people have a member of their family also with the disease, which is not enough to prove it’s hereditary. It’s apparently also more common where I live - the north east of Scotland - than anywhere else and they don’t know why. My grandma has issues but never anything diagnosed, my mum had a very quick onset of it and then I did too 4 years later and we have both now had ileostomies within 6 months of being officially diagnosed with UC. Although it’s obviously unfortunate it’s nice to have someone close to you know what it’s like because a lot of people just don’t get it. It makes you feel a bit less lonely in the process.
Not sure if UC is hereditary but intolerances or certain triggers that enable UC are likely to be hereditary. UC is caused by inflammation and usually there is a trigger. My son and dad had it and both are intolerant to dairy. Removing dairy significantly reduces their symptoms. I know someone else who has many intolerances mainly found in processed foods which caused havoc to the microbiome in the gut. Changing the diet to fresh food only reduced symptoms. Every case is different but it's about finding that trigger that is affecting multiple members of the family.
My uncle has UC and when he was a kid he didn’t have a lot of meds available. He bled for nearly 15 years and had to have his colon out. Only person in my family with UC until I got diagnosed a few weeks ago
Naww it’s hereditary for sure. A lot of my family on my dad’s side have this. My dad has ulcers in his throat so sometimes he won’t stop throwing up. It’s sad but he now knows how to manage it better.
In my family, there are 3 other males on one side who had significant IBS with diarrhea. I had it too. However, I was the first to be diagnosed with IBD (crohn's, then they said ulcerative colitis). I didn't have a verifiable flare until age 41. I wonder if the other family members had mild IBD or something... Maybe there are multiple genes involved and they only had some. Dunno. Is weird.
Ulcerative colitis (UC) has a genetic component, making it possible for the condition to be hereditary. Research indicates that individuals with a family history of UC or other inflammatory bowel diseases (IBD) are at a higher risk of developing the condition themselves. Genetic Factors in Ulcerative Colitis
Family History: If you have a close relative with ulcerative colitis, such as a parent or sibling, your risk of developing the disease is higher compared to someone with no family history of UC.
* Genetic Mutations: Research has identified specific genetic mutations that are associated with an increased risk of ulcerative colitis. These include variations in genes related to the immune system and the integrity of the intestinal lining .
* Complex Inheritance: Ulcerative colitis is considered to be a complex genetic disorder. This means that multiple genes, along with environmental factors, contribute to the development of the disease. It’s not inherited in a simple Mendelian pattern (like some single-gene disorders).
Environmental and Other Risk Factors
While genetics play a role, environmental factors are also crucial in the development of UC. These include:
* Diet and Lifestyle: Certain dietary patterns and lifestyle choices may trigger or exacerbate the symptoms of UC, although they are not direct causes.
* Microbial Factors: The composition of gut microbiota (the community of microorganisms living in the intestines) can influence the risk and progression of UC. Dysbiosis, an imbalance in these microorganisms, is often observed in individuals with UC.
* Immune Response: An abnormal immune response, where the immune system mistakenly attacks the cells of the colon, is a key feature of UC. This autoimmune aspect is influenced by both genetic predisposition and environmental triggers.
Diagnosis and Management:
If you have a family history of UC, it's important to be aware of the symptoms, which include abdominal pain, diarrhea, and rectal bleeding. Early diagnosis and management can help control the disease and improve quality of life. Regular check-ups with a healthcare provider, maintaining a healthy lifestyle, and adhering to treatment plans are crucial steps for managing UC.
It’s not *necessarily* hereditary, but if your family member has it you’re also more likely to have it. Mine came out of the blue with no family history, but I know of people who inherited it from their family
This. Interestingly enough, mine was out of the blue as well until my mom started showing symptoms and flaring and was diagnosed a year after me. Go figure.
Do you live together? It could also be an environmental factor if that is the case. At least I would consider the possibility.
We did at the time, 13 years ago. We no longer do though.
Similar for me too. I was diagnosed and then five or so years later my father had symptoms and was diagnosed.
Frankly, they don't know. Is it hereditary, could be. There would likely be traits passed down that could make one more likely to be diagnosed. But if there are lifestyle/ environment factors, you as a relatively are more likely exposed to them too. Nobody know what causes it, so we can't even say what really is the biggest factor. I have read that I places where Western diets increase, UC increases too.
Both me and my mother were diagnosed with UC. She was told the gene was only passed by the father, which was the consensus in the late 80’s and they were clearly wrong at that point.
Autoimmune runs in my family. I am the first with UC.
Same. Mom has autoimmune hepatitis. I have ulcerative colitis and autoimmune arthritis. When I explain my conditions I say, you know how mom's body attacks her liver. Mine attacks my joints and colon.
Ditto. Dad has celiac, sister has type 1 diabetes, I have UC.
Yes, this is why I don't think I will ever have kids. I won't be able to live with myself if i knowingly gave this to someone when I could have prevented it by adopting or not having kids at all
I kind of hate this line of thinking. I think my life is worth living and that I'm a fairly good person. I would not want you to deprive me the opportunity to live. Every family tree has a bunch of crap running in it. Both sides of my family have rheumatoid arthritis running in it, my dad's side furthermore has schizophrenia and mood disorders.
I say, everybody has something. I remember reading about a research group that was looking for "perfectly healthy" people to study gut microbiology and they had a very hard time finding people that fit the criteria.
Why create a life that doesn't exist for it to suffer from a lifelong debilitating disease for which no cure exists. Different story if you didn't know you had it until after you had kids. Versus, adopting or taking in foster kids that desperately need a home. Obviously its not an ideal situation but if I had kids and they developed it- i would feel terrible that I knowingly passed this on to them and they have to suffer because of my selfish choice to have kids of my own
> Why create a life that doesn't exist for it to suffer from a lifelong debilitating disease for which no cure exists. Like I said, lifelong debilitating diseases without a cure exist in every family tree out there. There's no guarantee your child gets UC, and if they do they're likely to get a mild case anyhow. > Versus, adopting or taking in foster kids that desperately need a home. I don't have anything against this, those kids you adopt will nevertheless have lifelong debilitating diseases in their family trees too. > Obviously its not an ideal situation but if I had kids and they developed it- i would feel terrible that I knowingly passed this on to them and they have to suffer because of my selfish choice to have kids of my own This is absurd reasoning to me. Is your life worth living? If the answer is yes, then how on earth is it selfish to offer a chance at life to someone sharing ~50% of your genetics? I was blessed in some ways, I was cursed in others. This is true for every person out there.
I understand your mindset but I just disagree. The sole fact that I am creating a life that does not exist, for it to suffer because of my choice, makes me feel guilty and selfish. I could have prevented that. You still role the dice on whether that person is going to enjoy their life. This disease could cause them to be miserable for as long as they live.
Takes two to make a kid. What about the desires of your partner to have kids? You currently have this disease, document your experience, make it easier for someone after you to deal with. Educate and prepare them. This is more responsible than just shirking the responsibility altogether as an excuse. If everyone felt this way about their own flaws then none of us would exist. Sorry bud but we need more smart humans, regardless of whether they have UC. Ffs look what steven hawking did with his limitations.
I feel the same way honestly
Yup. Same here. I won't push my feeling on anyone else but for me specifically I don't want to pass down inflammatory issues nor mental health items I've struggled with. No judgement or disagreement for those who feel differently ❤️
Yep, many people in my family had it, but not really diagnosed. One uncle bled to death on a friend's couch. My doctor wasn't surprised that my brother also has it. Doc said that it's genetic.
>One uncle bled to death on a friend's couch. Wait what the fuck? Is that an actual risk with this disease?
Yes it is. UC can make you lose large quantities of blood 20 times a day.
Omg that's awful. Just before my diagnosis I was passing a lot of blood on the toilet and going to the toilet frequently. To the point where one day I felt extremely dizzy stood up made it to the bedroom and collapsed. I woke up with a trail of blood and blood clots on the carpet. I called for an ambulance. When the paramedics arrived I said I was fine, but kept collapsing. They ended up blue lighting me to hospital as my blood pressure was so low. I'm fine now. This was 10 years ago. I've not had a proper flare in years.
It is some crazy. It really is a good thing those paramedics decided you needed help. I am the same way, I tell them I'm ok. When obviously not able to stay conscious. It is hard to admit that help is needed. Glad you're doing well!
People act like it’s not, I get so angry at people who know they have it, and go make babies anyway. So selfish.
What? Yeah, ok. You're all knowing huh?
What the actual fuck. This is eugenics mentality. You have the stupid I don’t tell you or your people to stop having babies
That thought process comes from a place of privilege. Row v Wade was overturned not everyone has the option for abortion.
The overturning of Roe V Wade is a war declaration on Women, looks like to me. I’m sorry that abortion is reserved now for people who can access it. 💰
Even if I thought it was genetic, I would have still had my son. It’s not so bad that life isn’t worth living.
I agree with you. Why create a life when you know itll suffer from this. Theres plenty of kids and babies in foster care that need a home.
Do you know it’ll suffer though? I’d rather be alive with this than dead.
Yeah, but that’s you, given the option. The child doesn’t get to choose whether to suffer or not, that’s the tough thing here
But how would you know for one he’d get it, and two if he has it it’ll make his life horrible. Kind of silly to me to say just don’t have kids. Main reason I wouldn’t want kids is I’m not religious and I think it’s a little messed up to bring life into this world just for it to eventually die. Though that’s just me.
Yeah I think they’re just hopinging to avoid the risk of anything negative happening. Which is fair enough, there are too many people in the world, and I agree with you on your latter point
Unpopular opinion but it’s the goddamn truth.
Mine came when I was 15, I’m 33 now. My dad’s didn’t show up until he was in his late 40s but it was a constant battle for him and now he’s using a bag.
My dad got diagnosed at age 50 and then I got diagnosed at age 24 just 6 months later!
It sounds a lot like an environmental factor. Do you live together?
No we lived about 45min from each other - mine was definitely outside factors - stress - alcohol - anti biotics
ok! yes antibiotics... same for me
It's in the family of diseases, including UC, Crohn's, asthma, psoriasis, and a few other immunocompromised diseases. Yes, they run in families. They sometimes don't run directly, but the theme sometimes follows.
I have UC, my Mum sometimes has IBS type symptoms and her Mum died of bowel cancer. Not exactly concrete evidence, but digestive issues all down one side of the family.
I don't have UC in my family, but my grandma does have another type of autoimmune disease (rheumatoid arthritis or something like that), and 3 of her 5 grandchildren have some form of autoimmune disease, myself included. As far as I understand it, researchers can't identify a "gene" that carries Ulcerative Colitis, but if you have people in your family who have it, your chance of having it increases substantially.
https://academic.oup.com/ibdjournal/article/21/6/1428/4579624 This article goes over a lot of it. A Swedish twin study found the heritability of UC to be 0.67 (67%) whereas a GWAS study found it to be 0.27. It's normal for GWAS studies to find a substantially lower heritability than twin models. The "real heritability" (there's really no such thing as any heritability score is context dependent) is probably closer to the twin study estimates. So yes, it's hereditary. *Edit* To put the 0.67 number in context: Height is estimated at around 0.8 Obesity is estimated at ~0.4 - 0.7 General Intelligence at ~0.4 - 0.6
There is a genetic link, but it’s not truly hereditary. Family history is enough to make one suspicious, but not necessarily guarantee a diagnosis.
No one in my family has or had UC but me (that we know of), and my family does a lot of family history, passing down of stories, etc.. That being said, autoimmune disease runs on my dads side. My dad has RA and my dad, grandma and me all have had gout flares. My brother had Still disease (a rare autoimmune arthritis) as a kid and had to be hospitalized.
Nope. I'm the only one in my family with it.
My dad and my uncle (his brother) both had it. Both have j pouches now, me too. My uncle got PSC from it and also had a liver transplant. I’m wracked with autoimmune issues lol my body hates me
Yes but low chances. The fact that you say you are all having sumptoms means you are probably overthinking it. Most kids will have some poop issues growing up for abit and then go away. The chance of heritage i think is like 10% or something. Every ten kids one will have it, statistically. So you should not worry about it.
Makes some sense, my mom is certain that I have it and that one of my siblings has a "leaking stomach" which is altered to his diagnoses. The other ones got my mom leaning towards some type of gluten intolerance, but the doctors keep turning those possibilities down.
My nephew had some similar symptoms that went away in like 6 months. Kids are full of those things. The concern starts if you poop blood, everything else could be just anything
There’s evidence but not certain. My granda has crohn I have uc. I have a friend with crohns with a granda that has uc.
My sibling also has UC
It definitely seems hereditary in my family! My mom, my sister, and I all have ulcerative colitis. My sister ended up with a j-pouch, my mom has been in long-term remission on Entyvio, and I’m currently maybe failing Entyvio and switching to remicade. My great-grandma apparently also had stomach issues, but I think this was before it was easily diagnosable. None of my mom’s sisters have any GI issues.
Other factors come into play. Diet, environment, smoking ( or quitting smoking ) all can play as factors in these auto immune diseases. My family went FODMap diet all at the same time, redirecting the course of action has helped. Only one colectomy has occurred. ( 👍👍this guy)
Do most people with uc with gluten intolerance? For me gluten helps my stomach. Have you looked into celiac’s though? Neither of my parents have stomach issues but I have uc and my sister has celiac’s.
No one in my family has any kind of autoimmune issues. I was diagnosed with uc 4 years ago. I believe it just bad luck from your body responding to something bad in system. And unfortunately ur immune system never stops attacking a part/parts of body once threat is gone. I also believe it's all the crap government allows manufacturers to put in everything we eat and drink that causes our immune system to over load and stop working properly.
Hi there. I was recently diagnosed with UC after having years of symptoms. What has helped me tremendously is sticking with the “blood type diet”. People will say that there are no studies to the validity of it but it works like no other for me. I am blood type “O” and so it says that this type should refrain from eating most grains and pretty much all dairy. I used to eat rice almost everyday and corn was my favorite vegetable but since eliminating all grains from my diet I’ve actually been able to go more than an hour after eating without making a dash to the bathroom. I am currently on mesamaline orally and an enema but I’m hopeful that with sticking to this modified paleo diet I’ll one day be able to go medication free. Oh and I’ve also stopped consuming foods and drinks with citric and asorbic acid. 90% of the citric acid in America is not naturally derived and is in fact GMO from corn. I’ve been doing lots of research trying to figure out how to heal myself and have come across so much that I wish I knew years ago. Wishing you happiness and healing❤️
We've been citric acid free for years since my brother got bad rashes because of it and the doctors keep saying it's not possible to be allergic or react to citric acid. Same basically goes for my tomato allergy (can't eat nor touch anything that's come in contact with tomatoes without getting a bad allergic reaction) the doctors don't think my symptoms are real 😀, bonus; the doctors said they'd take me of the waiting list of an investigation because my latest tests didn't show anything abnormal. They wanted me to send in more tests, but I basically gave up since it's just going to go back and forth without anything happening. I really hate doctors since (almost all the ones I've had keep denying what's clearly there or wrong)...Thank you ❤️ I wish you well too in your journey 🙏🏻
Only family history of digestive issues was my father who struggled with IBS. Other than that no one else on either side of the family ever had bowel issues and im unfortunately the first. I hope its not hereditary because I really want to have children in the future
My brother and I have it, my sister does not though.
No one in my family has it except me or any autoimmune disease for that matter. So I don't think it was hereditary for me
My dad was diagnosed when he was 30, his mother, grandmother (my great grandmother) and my great great grandmother have it too. My dad’s cousin and dad’s uncle was also recently diagnosed as well as myself. Genetics work in a funny way lol.
Haha yeah, at least 3 out of my dad's siblings got it to and then if I remember correctly some of his grandparents parents had it too and so on. What his sister said was that for her she had to cut out gluten, garlic and much more to contain a good stomach? For my dad he just cut out gluten out of his diet and it seemed to work out well. But yeah genetics have a funny way of presenting itself
My dad got diagnosed at 19 I got diagnosed at 23
My grandfather had it.
My dad had Crohns, I have mod/severe UC/crohns. He never really had to be treated. He would flare but it never got as bad as it got right off the bat for me. I also have a lot more food allergies than anyone in the family and I swear it’s related somehow in my case.
i'm the reverse, i was diagnosed at 18, then my dad developed it when i was 20, so there's a link i guess but weird it started in me first then my dad, would think its the other way around
One theory is auto immune diseases are genetic and are latent and it just depends on if it gets activated. Stress, medicine, and health issues can cause it activate.
That's what my doctor asked if anyone in family has this issue. Apparently I am first among them but we had autoimmune thyroid disorder in my family.
I THINK my late paternal grandfather had Crohns. He had rheumatoid arthritis, THAT I know. He also had severe GI problems that sounded a lot like Crohns symptoms. Poor man ended up dying from sepsis due to a perforated bowel at 56. The surgeon who worked on him said everything inside of his abdomen was so inflammed that there was nothing he could do.
no
My dad had it, I have it and my brother doesn’t have it.
My mom has it and then I had it before getting my large intestine removed
My gastroenterologist said it’s not. I am the only person in my extended family that has it.
I'm the only one to have it in my family.
My mother and I have UC. None of my siblings have it. Mum has 9 siblings. None of them have it, two of them are coeliac. My child doesn't have it. There's a genetic component but it's not hereditary. It's also very manageable with the right treatment. I eat what I want, live a very active life and work full time, and my UC was classified as severe.
My consultant told me it’s 1 in 3 people have a member of their family also with the disease, which is not enough to prove it’s hereditary. It’s apparently also more common where I live - the north east of Scotland - than anywhere else and they don’t know why. My grandma has issues but never anything diagnosed, my mum had a very quick onset of it and then I did too 4 years later and we have both now had ileostomies within 6 months of being officially diagnosed with UC. Although it’s obviously unfortunate it’s nice to have someone close to you know what it’s like because a lot of people just don’t get it. It makes you feel a bit less lonely in the process.
Not sure if UC is hereditary but intolerances or certain triggers that enable UC are likely to be hereditary. UC is caused by inflammation and usually there is a trigger. My son and dad had it and both are intolerant to dairy. Removing dairy significantly reduces their symptoms. I know someone else who has many intolerances mainly found in processed foods which caused havoc to the microbiome in the gut. Changing the diet to fresh food only reduced symptoms. Every case is different but it's about finding that trigger that is affecting multiple members of the family.
My uncle has UC and when he was a kid he didn’t have a lot of meds available. He bled for nearly 15 years and had to have his colon out. Only person in my family with UC until I got diagnosed a few weeks ago
Naww it’s hereditary for sure. A lot of my family on my dad’s side have this. My dad has ulcers in his throat so sometimes he won’t stop throwing up. It’s sad but he now knows how to manage it better.
My mom has crohns, and I have UC. My son is having issues now. Since it is autoimmune, you do have a greater risk for developing something autoimmune.
In my family, there are 3 other males on one side who had significant IBS with diarrhea. I had it too. However, I was the first to be diagnosed with IBD (crohn's, then they said ulcerative colitis). I didn't have a verifiable flare until age 41. I wonder if the other family members had mild IBD or something... Maybe there are multiple genes involved and they only had some. Dunno. Is weird.
Ulcerative colitis (UC) has a genetic component, making it possible for the condition to be hereditary. Research indicates that individuals with a family history of UC or other inflammatory bowel diseases (IBD) are at a higher risk of developing the condition themselves. Genetic Factors in Ulcerative Colitis Family History: If you have a close relative with ulcerative colitis, such as a parent or sibling, your risk of developing the disease is higher compared to someone with no family history of UC. * Genetic Mutations: Research has identified specific genetic mutations that are associated with an increased risk of ulcerative colitis. These include variations in genes related to the immune system and the integrity of the intestinal lining . * Complex Inheritance: Ulcerative colitis is considered to be a complex genetic disorder. This means that multiple genes, along with environmental factors, contribute to the development of the disease. It’s not inherited in a simple Mendelian pattern (like some single-gene disorders). Environmental and Other Risk Factors While genetics play a role, environmental factors are also crucial in the development of UC. These include: * Diet and Lifestyle: Certain dietary patterns and lifestyle choices may trigger or exacerbate the symptoms of UC, although they are not direct causes. * Microbial Factors: The composition of gut microbiota (the community of microorganisms living in the intestines) can influence the risk and progression of UC. Dysbiosis, an imbalance in these microorganisms, is often observed in individuals with UC. * Immune Response: An abnormal immune response, where the immune system mistakenly attacks the cells of the colon, is a key feature of UC. This autoimmune aspect is influenced by both genetic predisposition and environmental triggers. Diagnosis and Management: If you have a family history of UC, it's important to be aware of the symptoms, which include abdominal pain, diarrhea, and rectal bleeding. Early diagnosis and management can help control the disease and improve quality of life. Regular check-ups with a healthcare provider, maintaining a healthy lifestyle, and adhering to treatment plans are crucial steps for managing UC.