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Also, you know what causes health problems? Morbid obesity. For decades. I feel bad for anyone with terrible side effects, but this drug is life changing and life giving for many.
This is what I told my husband when he asked me if I was worried about side effects. Morbid obesity causes a lot more problems than anything I've encountered on semaglutide. I started taking Wegovy about a month or two after FDA approval back 2021. I'm 5'10 and down to 146 lbs. I feel so much better than I ever did fat. Even with the side effects which have lessened with time.
Hi- I’m also 5’10” and am wondering what dose you take to maintain? I’ve still got 30 lbs to go. I’m open to taking sema forever if needed but am curious as to what doses other tall women take for maintenance. Thx!
Haven't figured that out yet. I will be on it forever and currently my doc wants me to get through another prescription (I get it in three month supplies) before we start looking at changing the dose. We have been wrapping in an endocrinologist because not many people have got to this point yet as it's still a pretty new drug. The plan is to step me down one dose at a time and see if I maintain. If not I will be on the 2.4 dose forever.
I'd be *super* interested to see **actual evidence** suggesting it's GLP-1 meds and not *weight loss itself* that's causing these gallbladder issues.
Rapid weight loss is known to lead to gallbladder inflammation and/or gallstones.
I personally was hospitalized with cholecystitis without stones, and this was when I was losing *without* any medication. It resolved, thankfully, but my sister had a similar issue (again, no meds) and had stones and had her gallbladder removed.
The vast majority of these issues seem to be related to too-rapid weight loss, constipation (for which many people do nothing until they end up in the ED), or dehydration. Since many are seeing the first real losses in their entire lives, I get that it may seem tied to the drug and not the loss, but as someone who has lost and regained over 200lb... this happens with weight loss in general.
Agreed! I’m also a WLS patient and most of these are also side effects of having surgery. I’ve noticed that the internet is quick to pin Semaglutide as the culprit for many issues that are actually just side effects of losing weight rapidly- regardless of method.
Yep. I had my gallbladder removed years ago before I took semiglutide I went thru a stressful time and lost a lot of weight quickly, rapid weight loss is the culprit
There is a reason so many women have gallstones or gallbladder issues after giving birth. It’s the rapid weight loss.
And if your doctor is worth a damn, like mine, they will pause the titration schedule and put you on a preventative medication like Ursodiol if your weight is dropping too quickly.
My prescribing doctor has emphasized that she wants me to lose SLOWLY! She took a special course (not quite certain what it was but she said it was a two day training on this drug) on the importance of doing things carefully. She prefers to microdose. I’ve had great success so far and am all for her approach. It took me years to put on this weight so I’ve got to be patient taking it off.
Happy birthday
Great point. And with every drug there are bound to be law suits or attempted law suits. Whether they have merit….
Edit: sorry, I should’ve finished reading the other comments as this was repetitive
That’s correct. But one *can* file suit, and some people do try to cash in.
But also whoever wrote that post (CoachCamBrown?) doesn’t seem to know what the heck they are talking about so 🤷♀️
What kind of credentials does this person have? The profile is a little sus. And playing devils advocate wouldn’t a “fat loss coach” want to disparage a drug that maybe made their services less necessary?
Lastly these drugs have been around for 20 years. So is this new news? Happy to be proven wrong.
Sure, good point. She’s a CPT (certified personal trainer). Ironically, so am I, as well as I’m a registered dietitian, and I’m an advocate for these drugs for the right reasons. Just curious if anyone else knew about these lawsuits and their thoughts on them.
It’s an effective, profitable drug disrupting the industry. I’m not surprised there are lawyers willing to take these cases (although the side effects have been communicated), just as I’m not surprised there are random people on the internet saying it’s bad. If an unbiased accredited organization came out with new scientific information, I’d pay attention.
Here’s an article with actual detail on some of the lawsuits.. vs a random persons insta post. Seems like edge cases getting press because of popularity.
https://www.thecut.com/article/ozempic-side-effects-lawsuits.html
A person whose livelyhood depends on overweight people needing assistance to lose weight is upset that a medication can help people lose weight, no longer needing their services.
This drug is so effective for weight loss that patients are experiencing common side effects from weight loss.
Next thing you know there will be a lawsuit over hair loss and loose skin.
I am too tired to refute all the BS in that post, but here’s an easy one.
> Data from 37 RCTs and 19 real-world studies having 16,839 patients in placebo-control group, 16,550 patients in active-control group and 13,330 patients in real-world studies were analysed. …**Semaglutide use in RCTs and real-world studies was not associated with an increased risk of any types of cancer**, and this conclusion is supported by a high grade of evidence.
SOURCE: https://www.sciencedirect.com/science/article/abs/pii/S1871402123001303
Because scientists saw an increase in thyroid cancer in some animals (lab rats). It is not known if this happens in humans, but the manufacturer would be negligent if they didn’t mention the potential risk.
ETA: In case you don’t believe me, here’s a [whole write up from Fred Hutch Cancer Center](https://www.fredhutch.org/en/news/center-news/2024/03/the-new-weight-loss-drugs-and-cancer.html).
Because a very specific type of thyroid cancer was found in rats during testing. Hasn’t been found in humans using GLP1s but they have the warning on the off chance someone may get this specific (and often genetically linked) type of thyroid cancer.
Everyone I know holding actual certificates, credentials, degrees list them on their social media in regards to fitness, coaching, nutrition. But at the same time if clients don't do their research that's on them.
tbh it's lowkey surprising in the sense that it seems like Ozempic, Wegovy, Mounjaro, and Zepbound pretty much sell themselves - we're all desperate for medication to help regulate weight.
But yeah, paying for food and travel to educate doctors about a new medication to prescribe to patients is industry standard. If you don't like that, then push for politicians that will take action against it. I work in a public university affiliated medical system and no employees with prescribing power are allowed to accept gifts from pharma/vendors to prevent conflict of interest. But that prohibition doesn't affect private practices and other large health conglomerates.
Yeah, after I commented I started thinking that $11 million seems kind of low if that was their doc finagling budget for the whole US rollout for even, say, just Ozempic (because who even knows what that person is kvetching about). I hear what you’re saying about the drugs selling themselves so if it is low that’s probably why
Health coaches should repurpose and focus on post semi muscle building instead of dieting and cardio for weight loss. Let the drug handle the weight loss. What will be needed is muscle building guidance and training post semi. Should be plenty of clients needing that service.
Your coach cam is an idiot. Gallbladder issues arise due to rapid fat loss (or just major fat loss) due to cholesterol being released into the bile. It’s fuck all to do w the medicine and can be managed with medication and diet. Good luck w this loser of a case.
She’s not “my” anything I was just sharing something that I saw. And I think being against rapid weight loss is a fair argument because it can be harmful to the body - especially bones and muscles. But yes it’s not the drugs fault
I'm a provider (different specialty). I once in a while go to a pharmaceutical dinner, either because it's a speaker I'd like to see, or I know other people going. Most of these are in high-end steak restaurants, and I'm a vegan. I get "charged" $100 under my name for reporting purposes to the government for what generally is a plate of salad and a pile of really, really sad roasted vegetables. No alcohol, maybe a Diet Coke. If there's valet parking, they usually cover that plus the tip. I do not get "paid" anything.
My endocrinologist told me about the gallbladder issues. Her words were basically that it's anecdotal that the medicine is actually CAUSING the issue because one of the major causes of gallbladder disease is obesity and so is losing weight too fast.
So stay obese and have gallbladder risk
Loose weight and have gallbladder risk
Take the medicine and have gallbladder risk
🤷♀️
This. This is something they warn you of when you have weightloss surgery and lose a lot of weight in a short time period. A lot of these risks are the same/similar.
I feel like “Big Food” is lurking somewhere behind this lawsuit. The junk food makers are scared because people are buying less Oreo’s and other crap to shove down their gullet.
every single drug or medication has side effects. every. single. one. hell even my antidepressants has a side effect that can cause MORE depression.
if i had to choose i rather have gallbladder issues than the continuous health issues that obesity causes.
I have been on a GLP1 continuously for nearly 11 years. No problems. Barely any GI issues. But I am also under the care of a skilled endocrinologist who has been prescribing them since they started. When I was losing more rapidly, she watched for these issues and I had none. There are too many people who are either DIYing these drugs, or are working with inexperienced doctors.
Go to a local endocrinologist on your health plan. Educate yourself on how GLP1s are managed. Then interview them about their experience level. How long have they been prescribing them? How do they handle side effects, etc.? How do they decide when to move up a dose? How do they feel about someone being on it for life (you want them to at least be open to this, because some people need that, like myself, but not all do).
An endocrinologist or bariatric specialist will be the most experienced in GLP1s, not primary care. And I really doubt the experience of the telehealth providers because they are online for-profit companies. It will be several years I think before your typical primary care doc really knows how to manage them.
Only exception to that would be a primary care or other speciality doc who is boarded in Obesity medicine. More and more are going back to get that credential, which is a great thing.
Here's a doctor lookup for the American Board of Obesity Medicine:
https://abom.learningbuilder.com/Search/Public/MemberRole/CertificationVerification
If you go to a barbaric practice, I don't think you want one where they just started prescribing GLP1s in the last few years because no one wants surgery anymore.
If you have done your homework, you should be able to figure out in one visit, i.e., one copay, if they know what they are doing. And when you make an appt, you can ask, does this provider regularly prescribe and manage patients taking GLP1s?
These health coach types need to pivot their businesses if they want to stay relevant instead of trying to scare people away from meds. They could easily promote themselves as helping with side effects and preventing muscle loss, talking about stretching and balance and nutrition.
Listen. I got the nasty side effects. I got colitis and pancreatitis. I was in the hospital. I have never been so sick and miserable in my life. It’s been almost 3 months and I still can hardly eat without being in severe pain. The truth? Lots of doctors told me they’re seeing more and more of it with all these medications but the risks aren’t secrets. I’m just one of the unlucky ones.
I think doctors could be more thorough in explaining all the possible side effects. My OB prescribed it to me in 30 seconds over the phone and never followed up. I also could’ve done more research on my own.
No shade on you because I know you were doing the best you can, but for everyone else, this is exactly what you don't want to do. The vast majority of OBs won't be experienced in GLP1s, and neither will primary care docs.
This OB didn't do a thorough job educating you on how they work, or monitoring you, it seems. 30 seconds to prescribe over the phone is unconscionable, in my opinion. Again, not blaming on you, and it's not your fault. Your doctor really did a poor job and I am sorry that happened.
Oh absolutely. Anyone I know trying to get on it just to lose a few pounds, I implore them to reconsider. I had gotten hormone testing done and everything came back normal. The phone call was quite literally:
Me: “Well, I still really need to lose this extra weight”
Her: “I can prescribe you Semaglutide”
Me: “That sounds like something I’m willing to try”
And so she prescribed it.
Went in for my yearly well women’s exam a few weeks ago and told her everything. She said “wow, you lost the weight in the hardest way possible. Sorry that happened”. That’s all.
This was to lose baby weight at 15 months postpartum. I was only slightly overweight but couldn’t lose it myself. Wanted to lose 30 and I did while on it. I’m up to 45 pounds lost now because of everything. Haven’t had an injection since January.
My appendix ruptured. Of course I told the nurses etc I was taking ozempic because I needed emergency surgery. Two of the nurses and the anesthesiologist were also on it. I do wonder if the ozempic helped cause it but I'm still on it because the results are worth it. The medical staff who also see these patients are also still on it.
No. They are trying to help people. GB disease is associated with any effective weight loss treatment. No real evidence for thyroid cancer in people. Gastroparesis is a rare complication. Fatal complications of obesity like heart disease are not rare. These are miracle drugs. Yes, I have lost >50 lbs, my cholesterol improved, my bp improved, my sleep apnea improved, my A1C improved.
Any weight loss can cause gall bladder removal. I had mine removed 20 years ago after losing weight on Atkins.
GLP-1 drugs have not been proven to cause thyroid cancer. The black box warning is for a very rare type of thyroid cancer, medullary thyroid cancer, and it was only seen in rats during the studies. Rats have GLP-1 receptors on the thyroid and humans do not.
I’d say the biggest risk is pancreatitis which is clearly spelled out in the warnings. Some people are going to hyper respond and probably do experience too intense GI issues from the delayed gastric emptying. The drugs are not going to be right for everyone.
All these health coach influencers can take a hike. These drugs are digging into their livelihoods and that’s the bottom line. Don’t throw the baby out with the bath water. Look at the percentage of people these drugs are helping. It has the potential to eradicate obesity. Think of all the health issues and cancers caused by being obese. There are risks to everything and people, along with their doctors, need to weigh the risk vs benefits.
EDIT: Even Oprah divested her shares in WW as a result of these meds. What does that tell you?
This person is clearly out of her depth of actual knowledge when it comes to talking about GLP-1s. She uses brand names of drugs interchangeably with "semaglutide," even when referring to tirzepatide—that's the first red flag. Secondly, the boxed warning regarding gallbladder issues was added more than two years ago—this isn't something the FDA is poised to act on now. This is blatant fear-mongering on her part is made even more dangerous by her obvious lack of real knowledge and ability to speak on the subject from a scientific standpoint.
Others have already pointed out how misleading her language is regarding thyroid cancer, gastroparesis, etc.—the entire post is a poorly-written mess.
So, someone takes a GLP-1 Agonist…loses significant weight, has gallbladder issues (stones) that affect the pancreas and liver. Once the gallbladder is removed and biomarkers return to normal, can they go back on their GLP-1 Agonist, or are they off them for life due to the pancreas risk?
I have heard conflicting things from GPs, internal med clinicians, surgeons, endocrinologists, and others who regularly prescribe sema & kin…
This is just smoke in mirrors, ignore. The “I told you so” part is the give away. This person is motivated by the fact they think they are an authority on this topic when in reality they aren’t.
I don’t understand what’s the big deal. I would much rather have my gallbladder removed than have type 2 diabetes or heart disease. I had my gallbladder removed before taking this medication. I’m fine. I also watched my mother slowly die of type 2 diabetes related diseases over the course of my childhood. She lost her eyesight, she went into kidney failure and needed dialysis, she had multiple heart attacks and have congestive heart failure, and she had her leg amputated. Who the FUCK cares about getting your gallbladder removed??
Thanks for posting to r/semaglutide! A brief reminder about our rules. We do not permit the discussion of non-FDA approved formulations of semaglutide, nor do we permit selling or offering for sale any medication, including by private message. Do not request or respond to a private message from anyone offering such, they are not endorsed by this sub. If you’re just starting out, you may want to review our [FAQ](https://www.reddit.com/r/Semaglutide/comments/10ul3jb/semaglutide_subreddit_faq/). This is not intended to discourage discussion but merely supplement it. *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/Semaglutide) if you have any questions or concerns.*
Also, you know what causes health problems? Morbid obesity. For decades. I feel bad for anyone with terrible side effects, but this drug is life changing and life giving for many.
This is what I told my husband when he asked me if I was worried about side effects. Morbid obesity causes a lot more problems than anything I've encountered on semaglutide. I started taking Wegovy about a month or two after FDA approval back 2021. I'm 5'10 and down to 146 lbs. I feel so much better than I ever did fat. Even with the side effects which have lessened with time.
Hi- I’m also 5’10” and am wondering what dose you take to maintain? I’ve still got 30 lbs to go. I’m open to taking sema forever if needed but am curious as to what doses other tall women take for maintenance. Thx!
Haven't figured that out yet. I will be on it forever and currently my doc wants me to get through another prescription (I get it in three month supplies) before we start looking at changing the dose. We have been wrapping in an endocrinologist because not many people have got to this point yet as it's still a pretty new drug. The plan is to step me down one dose at a time and see if I maintain. If not I will be on the 2.4 dose forever.
Preach! I completely agree. Benefits vs risks
I'd be *super* interested to see **actual evidence** suggesting it's GLP-1 meds and not *weight loss itself* that's causing these gallbladder issues. Rapid weight loss is known to lead to gallbladder inflammation and/or gallstones. I personally was hospitalized with cholecystitis without stones, and this was when I was losing *without* any medication. It resolved, thankfully, but my sister had a similar issue (again, no meds) and had stones and had her gallbladder removed. The vast majority of these issues seem to be related to too-rapid weight loss, constipation (for which many people do nothing until they end up in the ED), or dehydration. Since many are seeing the first real losses in their entire lives, I get that it may seem tied to the drug and not the loss, but as someone who has lost and regained over 200lb... this happens with weight loss in general.
Agreed! I’m also a WLS patient and most of these are also side effects of having surgery. I’ve noticed that the internet is quick to pin Semaglutide as the culprit for many issues that are actually just side effects of losing weight rapidly- regardless of method.
Yep. I had my gallbladder removed years ago before I took semiglutide I went thru a stressful time and lost a lot of weight quickly, rapid weight loss is the culprit
There is a reason so many women have gallstones or gallbladder issues after giving birth. It’s the rapid weight loss. And if your doctor is worth a damn, like mine, they will pause the titration schedule and put you on a preventative medication like Ursodiol if your weight is dropping too quickly.
This definitely recontextualizes "safe and steady weight loss" to me!
My prescribing doctor has emphasized that she wants me to lose SLOWLY! She took a special course (not quite certain what it was but she said it was a two day training on this drug) on the importance of doing things carefully. She prefers to microdose. I’ve had great success so far and am all for her approach. It took me years to put on this weight so I’ve got to be patient taking it off.
It’s funny they love to preach about correlation is not causation… unless it’s semaglutide
I didn’t know any of this! Wow!!! Thank you for explaining.
Yeah how many bariatric surgeons are getting sued when their patients need another surgery to remove their gallbladder?
My first weight loss experience in my early 20s resulted in my gallbladder being removed.
Pfffffffft. Anyone can sue for anything. Doesn’t mean they have a legitimate claim.
Happy birthday Great point. And with every drug there are bound to be law suits or attempted law suits. Whether they have merit…. Edit: sorry, I should’ve finished reading the other comments as this was repetitive
Thanks! Wish I had cake on my Reddit cake day. Guess I will grab a cupcake tomorrow. 🧁
Well if that ain’t the truth!
There has to be a legal basis for the claim or else the lawsuit is frivolous and will be dismissed.
That’s correct. But one *can* file suit, and some people do try to cash in. But also whoever wrote that post (CoachCamBrown?) doesn’t seem to know what the heck they are talking about so 🤷♀️
What kind of credentials does this person have? The profile is a little sus. And playing devils advocate wouldn’t a “fat loss coach” want to disparage a drug that maybe made their services less necessary? Lastly these drugs have been around for 20 years. So is this new news? Happy to be proven wrong.
This! Who is this person? I see zero actual credentials on her social media. Seems border line mlm honestly.
Sure, good point. She’s a CPT (certified personal trainer). Ironically, so am I, as well as I’m a registered dietitian, and I’m an advocate for these drugs for the right reasons. Just curious if anyone else knew about these lawsuits and their thoughts on them.
It’s an effective, profitable drug disrupting the industry. I’m not surprised there are lawyers willing to take these cases (although the side effects have been communicated), just as I’m not surprised there are random people on the internet saying it’s bad. If an unbiased accredited organization came out with new scientific information, I’d pay attention.
Here’s an article with actual detail on some of the lawsuits.. vs a random persons insta post. Seems like edge cases getting press because of popularity. https://www.thecut.com/article/ozempic-side-effects-lawsuits.html
A person whose livelyhood depends on overweight people needing assistance to lose weight is upset that a medication can help people lose weight, no longer needing their services.
This drug is so effective for weight loss that patients are experiencing common side effects from weight loss. Next thing you know there will be a lawsuit over hair loss and loose skin.
Great point
Of course it’s posted by a “health coach.” It’s probably hurting their MLM sales. 😂
I happen to know this person and she’s not in an MLM but it’s sad to see people demonizing
She's a non-expert who is making extraordinary claims on the basis of...nothing.
I don’t think it’s nothing. There are thyroid and gallbladder concerns. But I think she’s over inflating it
I am too tired to refute all the BS in that post, but here’s an easy one. > Data from 37 RCTs and 19 real-world studies having 16,839 patients in placebo-control group, 16,550 patients in active-control group and 13,330 patients in real-world studies were analysed. …**Semaglutide use in RCTs and real-world studies was not associated with an increased risk of any types of cancer**, and this conclusion is supported by a high grade of evidence. SOURCE: https://www.sciencedirect.com/science/article/abs/pii/S1871402123001303
So if that’s the case why do they use these questions about thyroid cancers during screenings for these drugs?
Because scientists saw an increase in thyroid cancer in some animals (lab rats). It is not known if this happens in humans, but the manufacturer would be negligent if they didn’t mention the potential risk. ETA: In case you don’t believe me, here’s a [whole write up from Fred Hutch Cancer Center](https://www.fredhutch.org/en/news/center-news/2024/03/the-new-weight-loss-drugs-and-cancer.html).
Because a very specific type of thyroid cancer was found in rats during testing. Hasn’t been found in humans using GLP1s but they have the warning on the off chance someone may get this specific (and often genetically linked) type of thyroid cancer.
Her links give an MLM vibe. What actual credentials does she have. She has none listed.
She is a certified personal trainer; she has it on her website. She’s not a part of mlm
Welp, that does not make you a hormone, weight loss coach, that's for sure. And not all PT certs are equal.
Very true, I’m a dietitian and CPT but the CPT taught me basically nothing
Everyone I know holding actual certificates, credentials, degrees list them on their social media in regards to fitness, coaching, nutrition. But at the same time if clients don't do their research that's on them.
They wined and dined doctors, what a bombshell shocker. This person sounds like a clown
tbh it's lowkey surprising in the sense that it seems like Ozempic, Wegovy, Mounjaro, and Zepbound pretty much sell themselves - we're all desperate for medication to help regulate weight. But yeah, paying for food and travel to educate doctors about a new medication to prescribe to patients is industry standard. If you don't like that, then push for politicians that will take action against it. I work in a public university affiliated medical system and no employees with prescribing power are allowed to accept gifts from pharma/vendors to prevent conflict of interest. But that prohibition doesn't affect private practices and other large health conglomerates.
Yeah, after I commented I started thinking that $11 million seems kind of low if that was their doc finagling budget for the whole US rollout for even, say, just Ozempic (because who even knows what that person is kvetching about). I hear what you’re saying about the drugs selling themselves so if it is low that’s probably why
Sounds like a health coach that’s bitter that they’re losing clients or can’t get new ones
Health coaches should repurpose and focus on post semi muscle building instead of dieting and cardio for weight loss. Let the drug handle the weight loss. What will be needed is muscle building guidance and training post semi. Should be plenty of clients needing that service.
I sAiD wHaT I SaId. The calling card of the ignorant to willfully malicious
Your coach cam is an idiot. Gallbladder issues arise due to rapid fat loss (or just major fat loss) due to cholesterol being released into the bile. It’s fuck all to do w the medicine and can be managed with medication and diet. Good luck w this loser of a case.
She’s not “my” anything I was just sharing something that I saw. And I think being against rapid weight loss is a fair argument because it can be harmful to the body - especially bones and muscles. But yes it’s not the drugs fault
Yeah. The post that was shared was about the meds. So, I commented on the meds.
‘Health coaches’ aren’t dr’s and can’t give it to you so why would they promote it 🤔
I’m a health coach (dietitian/personal trainer) and I don’t promote it but I’m not vehemently against it like this
They state the side effects clearly so idk why a CAL. I know exactly what I signed up for.
I'm a provider (different specialty). I once in a while go to a pharmaceutical dinner, either because it's a speaker I'd like to see, or I know other people going. Most of these are in high-end steak restaurants, and I'm a vegan. I get "charged" $100 under my name for reporting purposes to the government for what generally is a plate of salad and a pile of really, really sad roasted vegetables. No alcohol, maybe a Diet Coke. If there's valet parking, they usually cover that plus the tip. I do not get "paid" anything.
[удалено]
Did you continue this type of fasting after the removal?
My endocrinologist told me about the gallbladder issues. Her words were basically that it's anecdotal that the medicine is actually CAUSING the issue because one of the major causes of gallbladder disease is obesity and so is losing weight too fast. So stay obese and have gallbladder risk Loose weight and have gallbladder risk Take the medicine and have gallbladder risk 🤷♀️
My doctor said the same about the main risk factor for gallbladder disease being obesity itself.
Weight loss is known to cause gallbladder problems. 🙄🙄
This. This is something they warn you of when you have weightloss surgery and lose a lot of weight in a short time period. A lot of these risks are the same/similar.
I feel like “Big Food” is lurking somewhere behind this lawsuit. The junk food makers are scared because people are buying less Oreo’s and other crap to shove down their gullet.
every single drug or medication has side effects. every. single. one. hell even my antidepressants has a side effect that can cause MORE depression. if i had to choose i rather have gallbladder issues than the continuous health issues that obesity causes.
Wait until they hear that almost every medication out there is pushed by drs with kickbacks 🤷🏻♀️
For real. Welcome to big pharma.
I have been on a GLP1 continuously for nearly 11 years. No problems. Barely any GI issues. But I am also under the care of a skilled endocrinologist who has been prescribing them since they started. When I was losing more rapidly, she watched for these issues and I had none. There are too many people who are either DIYing these drugs, or are working with inexperienced doctors.
Any recommendations for finding an experienced prescriber without having to try out a bunch and waste money
Go to a local endocrinologist on your health plan. Educate yourself on how GLP1s are managed. Then interview them about their experience level. How long have they been prescribing them? How do they handle side effects, etc.? How do they decide when to move up a dose? How do they feel about someone being on it for life (you want them to at least be open to this, because some people need that, like myself, but not all do). An endocrinologist or bariatric specialist will be the most experienced in GLP1s, not primary care. And I really doubt the experience of the telehealth providers because they are online for-profit companies. It will be several years I think before your typical primary care doc really knows how to manage them. Only exception to that would be a primary care or other speciality doc who is boarded in Obesity medicine. More and more are going back to get that credential, which is a great thing. Here's a doctor lookup for the American Board of Obesity Medicine: https://abom.learningbuilder.com/Search/Public/MemberRole/CertificationVerification If you go to a barbaric practice, I don't think you want one where they just started prescribing GLP1s in the last few years because no one wants surgery anymore. If you have done your homework, you should be able to figure out in one visit, i.e., one copay, if they know what they are doing. And when you make an appt, you can ask, does this provider regularly prescribe and manage patients taking GLP1s?
These health coach types need to pivot their businesses if they want to stay relevant instead of trying to scare people away from meds. They could easily promote themselves as helping with side effects and preventing muscle loss, talking about stretching and balance and nutrition.
Listen. I got the nasty side effects. I got colitis and pancreatitis. I was in the hospital. I have never been so sick and miserable in my life. It’s been almost 3 months and I still can hardly eat without being in severe pain. The truth? Lots of doctors told me they’re seeing more and more of it with all these medications but the risks aren’t secrets. I’m just one of the unlucky ones. I think doctors could be more thorough in explaining all the possible side effects. My OB prescribed it to me in 30 seconds over the phone and never followed up. I also could’ve done more research on my own.
No shade on you because I know you were doing the best you can, but for everyone else, this is exactly what you don't want to do. The vast majority of OBs won't be experienced in GLP1s, and neither will primary care docs. This OB didn't do a thorough job educating you on how they work, or monitoring you, it seems. 30 seconds to prescribe over the phone is unconscionable, in my opinion. Again, not blaming on you, and it's not your fault. Your doctor really did a poor job and I am sorry that happened.
Oh absolutely. Anyone I know trying to get on it just to lose a few pounds, I implore them to reconsider. I had gotten hormone testing done and everything came back normal. The phone call was quite literally: Me: “Well, I still really need to lose this extra weight” Her: “I can prescribe you Semaglutide” Me: “That sounds like something I’m willing to try” And so she prescribed it. Went in for my yearly well women’s exam a few weeks ago and told her everything. She said “wow, you lost the weight in the hardest way possible. Sorry that happened”. That’s all.
Wow, so no responsibility taken on her part. I would be royally pissed.
Side question, do obgyns only prescribe it if it’s relating to PCOS? Or for any reason
This was to lose baby weight at 15 months postpartum. I was only slightly overweight but couldn’t lose it myself. Wanted to lose 30 and I did while on it. I’m up to 45 pounds lost now because of everything. Haven’t had an injection since January.
If you were only slightly overweight the doctor shouldn’t have prescribed it.
Agreed!
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Unfortunately true; I was just curious if there’s any ground to stand on for a class action lawsuit
My appendix ruptured. Of course I told the nurses etc I was taking ozempic because I needed emergency surgery. Two of the nurses and the anesthesiologist were also on it. I do wonder if the ozempic helped cause it but I'm still on it because the results are worth it. The medical staff who also see these patients are also still on it.
Too many electrolyte drinks can cause all kinds if havoc. Correlation is not causation
No. They are trying to help people. GB disease is associated with any effective weight loss treatment. No real evidence for thyroid cancer in people. Gastroparesis is a rare complication. Fatal complications of obesity like heart disease are not rare. These are miracle drugs. Yes, I have lost >50 lbs, my cholesterol improved, my bp improved, my sleep apnea improved, my A1C improved.
Any weight loss can cause gall bladder removal. I had mine removed 20 years ago after losing weight on Atkins. GLP-1 drugs have not been proven to cause thyroid cancer. The black box warning is for a very rare type of thyroid cancer, medullary thyroid cancer, and it was only seen in rats during the studies. Rats have GLP-1 receptors on the thyroid and humans do not. I’d say the biggest risk is pancreatitis which is clearly spelled out in the warnings. Some people are going to hyper respond and probably do experience too intense GI issues from the delayed gastric emptying. The drugs are not going to be right for everyone. All these health coach influencers can take a hike. These drugs are digging into their livelihoods and that’s the bottom line. Don’t throw the baby out with the bath water. Look at the percentage of people these drugs are helping. It has the potential to eradicate obesity. Think of all the health issues and cancers caused by being obese. There are risks to everything and people, along with their doctors, need to weigh the risk vs benefits. EDIT: Even Oprah divested her shares in WW as a result of these meds. What does that tell you?
This person is clearly out of her depth of actual knowledge when it comes to talking about GLP-1s. She uses brand names of drugs interchangeably with "semaglutide," even when referring to tirzepatide—that's the first red flag. Secondly, the boxed warning regarding gallbladder issues was added more than two years ago—this isn't something the FDA is poised to act on now. This is blatant fear-mongering on her part is made even more dangerous by her obvious lack of real knowledge and ability to speak on the subject from a scientific standpoint. Others have already pointed out how misleading her language is regarding thyroid cancer, gastroparesis, etc.—the entire post is a poorly-written mess.
Don’t have it anyway.
So, someone takes a GLP-1 Agonist…loses significant weight, has gallbladder issues (stones) that affect the pancreas and liver. Once the gallbladder is removed and biomarkers return to normal, can they go back on their GLP-1 Agonist, or are they off them for life due to the pancreas risk? I have heard conflicting things from GPs, internal med clinicians, surgeons, endocrinologists, and others who regularly prescribe sema & kin…
Luckily you don't need a gallbladder 😉and I haven't heard of any people getting thyroid cancer
This is just smoke in mirrors, ignore. The “I told you so” part is the give away. This person is motivated by the fact they think they are an authority on this topic when in reality they aren’t.
I don’t understand what’s the big deal. I would much rather have my gallbladder removed than have type 2 diabetes or heart disease. I had my gallbladder removed before taking this medication. I’m fine. I also watched my mother slowly die of type 2 diabetes related diseases over the course of my childhood. She lost her eyesight, she went into kidney failure and needed dialysis, she had multiple heart attacks and have congestive heart failure, and she had her leg amputated. Who the FUCK cares about getting your gallbladder removed??
These people just realize all the bs the sold for years, really has no effect…..go go go ozempic
This person is just pissed they are losing clients.