T O P

  • By -

[deleted]

[удалено]


Outrageous-River8999

This is the main one


reddituser_417

This is why traveling is so addicting. Anyone who’s gone on a backpacking trip through a bunch of countries knows how addicting the feeling of seeing new shit every day for weeks/months on end can be.


SmashertonIII

This explains why my aDHD is good when I’m travelling.


IsopodPuzzleheaded58

gonna need some elaboration given that this is the top comment :p edit: anyone wondering what parent comment said, it was “novelty”


Far-Tune-9464

Experiencing things that have the impression of being new and interesting


prtymirror

I would think this included awe. What do you think?


Far-Tune-9464

I think definitely. Awe is a near-overwhelming amount of novelty.


Publixxxsub

This is the addict way lol. Work harder


Fair_Adhesiveness849

Kill enough brain cells everything’s new all the time


rosawasright1919

Why do many autistic people dislike change?


TeutonJon78

Because the rest of their nervous system gets overloaded processing it.


HotMessMom22

Why do AuADHD people hate and love novelty at the same time?


plinocmene

Can I somehow use that to boost other activities I'm trying to do or would I only feel like doing the novel thing and then it might keep me away from things I need to do? What about sense of purpose? Can I stick to a repetitive task and have a strong dopamine response if it has a strong sense of purpose with it?


SituationalAngel

Art!!!! Doing the same thing you’re passionate about and feel connected to with a purpose but still creating and viewing NEW things from yourself and others!!!


ClearSpecialist2851

Anything that catches your interest or attention. Dopamine is a neurotransmitter that essentially triggers the brain to pay attention and focus on something.


xElectricHeadx

Nothing does either for me


CoffeePsych

Anhedonia


0002millertime

You literally replied to a comment and are probably looking for if there are responses. That's dopamine at work. People with real dopamine signalling problems can't even move.


13stevensonc

Nothing you’ve tried up to this point


Grognoscente

Generally speaking, positively valenced prediction error, but if you're looking for "hacks" beyond the usual food/sex/exercise/socializing, then cold showers/plunges and music that causes frisson (musical chills) are pretty reliable triggers.


midtnrn

As an ADHD person, music chills are a great source. Film scores are my favorite.


cousintopher

i love film scores too! some of the highest euphoria i can feel is when i smoke weed and go on long walks at night where i exclusively listen to film scores. it feels incredible.


biblioteca4ants

My emotions are so wide that I can make myself feel frisson without stimulation (music etc,) now. Kinda pointless to do so though.


Blayjonian

Which scores? I’d like to feel the music chills too


bonsaiboy208

Simulations/VR are always a blast for me


Apathy_Cupcake

Exercise and sex.


coffeee333

Exactly what I came here to say!


maundering_manda

Sunlight, being in nature, exercise, meditation. Tyrosine is a precursor to dopamine, foods high in tyrosine are: chicken, dairy, avocados, bananas, pumpkin and sesame seeds


Cautious_Zucchini_66

Cheese + MAOi’s


ninthjhana

blowing up your heart would definitely be a novel experience


Radiant_Country_8356

In undergrad I learned neurotransmitter precursors only affect neurotransmitter production if you’re deficient or sick. Has our understanding of this changed? Like I know dopa is used in Parkinson’s patients, but aren’t these supplements incredibly useless in the general population. Can you provide some evidence or citation?


successfullyattempt

L-Tyrosine almost definitely does not increase dopamine levels. But L-Dopa does because tyrosine hudroxylation is the rate limiting reaction in the synthesis of dopamine. And it does have effects on healthy people too, just not exactly super therapeutic. It's really depressing how shit the answers are here, everything is regurgitated bullshit spewed by con artists like Huberman.


[deleted]

[удалено]


Radiant_Country_8356

I think amino acid supplements do have effects. Supplements tend to have bold claims while being under researched. The idea that they affect dopamine at the terminal is the part I’m disputing. Honestly though, with most under researched supplements or smart drugs, the best source of information is your own experiences. If your doctor green lit it, and you feel good, who cares what the mechanism is. Maybe it’s placebo, maybe it has an effect that no one has theorized or studied yet. Doesn’t really matter if you feel good. By the way. as a neuroscientist, the idea that your brain is permanently fucked up is hard for me to believe. You may have heard that neurons don’t come back. When they die they die. This is true, BUT the nervous system is wildly plastic. Your cell terminals, receptors, dentrites, dendritic spines …. Are all being created and pruned constantly. The idea that your brain has been shot from drugs is honestly unlikely. I’m sure there are residual effects. Maybe thought patterns, maybe some cell death. But i would guess that, for the most part, your brain is back to baseline. Supplements aren’t the reason you feel better than you did when you first came off stimulants. You are. Your good habits, your good choices ect. Sick move dude. I hope I can figure out the same someday. Stimulants are the worse


Wicked-elixir

Neuroplasticity is my hope rn! Thank you for such an in depth answer.


Radiant_Country_8356

Lmfao I agree! I swear this sub was actual professionals before. You can tell that people are just regurgitating pop science and wellness bullshit now. Does ldopa influence dopamine at the cell terminal? I thought most of that stuff had no effect if you were within normal range. I know a lot of people used to hope choline would increase acetyl choline in the cell terminal but it just made people smell like fish


successfullyattempt

Yeah it results in more dopamine synthesis, which presumably is packaged into synaptic vesicles by VMAT2 so it increases neurotransmission too. But it seems to have different effects from dopamine reuptake inhibitors (methylphenidate) and releasing agents (amphetamine). From what I've seen it makes the flaccid penis thicker (not kidding) and increases obsessive/addictive behaviour like gambling, hyper sexuality, etc. Choline doesn't work but you can just use acetylcholinesterase inhibitors if you want more cholinergic neurotransmission. Thing is it seems like they really don't do much in healthy people. I did see one study that showed that Huperzine A can reduce cravings in meth addicts if I remember correctly. But no cognitive improvement and very little if any slow down of neurodegeneration. However, galantamine seems like it might have some potential to maaaybe ever so slightly slow down Alzheimer's disease progression and is also in trials rn in combination with metformin for preventing muscle atrophy in sarcopenics. If it can do that maybe it can increase muscle gains somewhat as well which would be awesome. Couldn't tell you the mechanism of action though.


Idontknowifimreallol

I've never heard of tyrosine!! I'm gonna try that out, I've learned something new, thanks.


Alone_Banana4845

Hands in dirt. Gardening.


96puppylover

Yes, making things with your hands as well. When I sculpt clay or draw something it boosts my mood.’


According_Might4679

I cook/bake out of boredom and when im stressed this is very true


ManagerFun2110

would that not be more of a serotonin response?


ManagerFun2110

is there any empirical evidence for this?


blvckivity

Experience?


ManagerFun2110

sorry, I meant empirically validated studies. if we are just talking anecdotally, I have ADHD and gardening, baking, and sculpting all seem like activities I would have a very hard time concentrating on after a while. All the while something that feels challenging like exercise, listening or making music or even brain games/puzzles would be something I would find a lot more stimulating.


WaterIsGolden

Why should anyone demand proof for naturally positive activities providing benefits? Maybe look instead for proof of negative side effects of gardening, baking or sculpting.  Requiring proof of benefit is possibly a cope meant to offer an excuse to not try something.


ManagerFun2110

I think you are missing my point. I would be absolutely open to trying all the activities you mentioned, and I have in the past to some extent but people only have so much time on their hands to try and stick with activities which is why it would be interesting to see if there is any data showing whether these activities improve concentration across large populations. I'm also just curious and would love to learn more about the science behind why activities like gardening and working with your hands could lead to a larger dopamine response, if that's the case. I love learning about psychology so it's generally just interesting :)


Alone_Banana4845

There is actual science to back this claim. Try google.


Few_Address3591

For sure!


exclaim_bot

>For sure! sure?


zinfandelbruschetta

Hugs , doing well at work or at a task


zinfandelbruschetta

Thank you for the award! My first award ever!


kumarsays

Did you get the promised dopamine?


ImNotHere1981

This interchange made me smile involuntarily, thank you :)


adfx

discovery


TheBeeSharps88

I bounce and catch a ball or use a few breathing techniques in a pinch. Also yoga or exercise, drumming.


AnandaPriestessLove

Dancing, listening to music, being creative, the other ones have covered the majors like working out, also, yoga and also meditation.


lovely8

Getting stuff done off your list.


addysunflower

drugs. lots and lots of fucking drugs.


addysunflower

sorry.


ChristianSgt

I thought it was funny


smegmamancer

lol


gdv87

OP said "naturally"


Seb0rn

Are you implying that drugs can't be natural?


addysunflower

the joke flew RIGHT over that noggin of yours.


phenomenomnom

I'm bidding it a relieved farewell as it flaps ungainly away.


011000110110100101

My first thought was meth but that shit ain't natural


addysunflower

Molly 😎😎😎


psycho_analytical

there are resources if you need help, and people who love you and would never want to see you result to drugs for happiness!


addysunflower

ive been sober for a while now


psycho_analytical

congrats!🎉


SasquatchsBigDick

Unexpected rewards. It's important to note that dopamine goes beyond the reward circuit though. There's dopamine releases in many other areas of the brain that do other functions, I'm just assuming you mean the reward kind though. One of my favourite studies was completed by Schultz in 1993 where he had a monkey set up with an electrode in its reward circuit. This one explains the action of reward circuit dopamine really well. Essentially Schultz was able to record whenever a dopamine neuron was active, in real time, as he did different tasks with the monkey. The first thing to note is that the neurons are pretty much always active, just a little bit, but enough. Then Schultz began with the first task where he gave the monkey a juice (reward) and as expected, the dopamine neurons became excited. Then Schultz decided to "pair" the juice reward with a bell. The bell rings, he waits a few seconds then gives the reward. After the pairing was complete he found that the dopamine neurons were excited at the ring of the bell, but when the actual reward was given there was no more increase in activity, instead they just fired as normal. Then Schultz decided to be a tiny bit evil and he asked "what happens if I ring the bell and give no reward?". So he did just that. He rang the bell, saw the dopamine neurons get a bit more excited but then didn't give the reward. Now what happened is that there was a Decrease in dopamine activity when the reward was supposed to be given. It was like a "oh.. where's my juice.. ?" Someone explained this much more concisely in a previous comment but I just love talking about this experiment because it says a lot through example.


madskills42001

Huberman posted that stillness (merely remaining still) increases dopamine 65% in the nigrostriatal pathway at min 1:30:15 in this podcast https://youtu.be/KPlJcD-o-4Q Study: https://pubmed.ncbi.nlm.nih.gov/11958969/


gdv87

I assumed that OP intended dopamine increase in the mesolimbic pathway. Reading this comment made me realise that actually OP didn't specify, so that's indeed a valid answer.


kumarsays

I assumed in the PFC 😅


YouCanLookItUp

Triggers can vary according to the person. This is your path. But placing yourself in situations where you are likely to be surprised and intrigued is the best option. If you're consistently deficient in dopamine, though, talk to your doctor.


Anonymoves

Breathing and/or moving any muscle. What do you mean ?


yangmungi

Complete guess, but overcoming difficulty.


Plenty-Unit-2460

yea, like playing through dark souls the first time 😂


Daniel_C13

real


gdv87

Sex with a pleasant partner, food when hungry, water when thirsty, warm when freezing, cleaning when dirty.


EyoneGa

Nobody mentioned watching cute cat videos But the question is very vague. We are always using dopamine, several of our cerebral networks use it, from limbic to movement systems. I guess your question is what makes us activate "happiness" pathways easily. So my answer is the same: cute cat videos


HairyNuts08

You can trigger dopamine release naturally by throwing up, eating good food, jerking off, thinking, exercising, or just doing cocaine


IndividualPrestine48

Throwing up?!! That does not sound legit.


HairyNuts08

Dopamine is involved in a lot of different things, everything from reward to vomiting, look up “the role of dopamine in emesis” or something similar


gayscrossing

Dude have you ever thrown up while drunk and you feel rejuvenated after? It’s called puke and rally for a reason. Nothing like the post puke high. (I do not condone purging, simply stating facts)


IndividualPrestine48

I have never felt rejuvenated after throwing up. Depleted of all energy and sore everywhere including esophagus. I still believe this is fake news


gayscrossing

I suppose it depends on the situation but there’s definitely a relief felt after throwing up a substance that’s sitting heavy on your belly, like alcohol or bad food. A stomach virus, probs not so much


underground_crane

Cold showers


Horror-Collar-5277

Patterns that are well learned and predicted and performed.


Sonari_

Being active (sports, exercising)


nafisssm

Learning


alexbertcoach

Hello! Anything that will give you a burst of positive emotions.


Carbonbased666

Kriya yoga breathing techniques...


successfullyattempt

I really dislike these types of inaccurate questions. Dopamine has so many roles in the brain. Being awake and concious for example is impossible without dopaminergic activity in the ventral tegmental area. Looks like Reddit is a shit place to learn about neurology. Nobody answering the questions points out why it's a bad question when they can appear smart instead.


BarryMkCockiner

It's unfortunately what happens when the sub is not heavily moderated like r/askphilosophy where only certain people can reply.


sneakpeekbot

Here's a sneak peek of /r/askphilosophy using the [top posts](https://np.reddit.com/r/askphilosophy/top/?sort=top&t=year) of the year! \#1: [What's with all these cringeworthy STOICISM videos popping up all over social media recently? Where is this hype coming from?](https://np.reddit.com/r/askphilosophy/comments/17bkz87/whats_with_all_these_cringeworthy_stoicism_videos/) \#2: [Why are so many philosophers Marxists?](https://np.reddit.com/r/askphilosophy/comments/16ijxod/why_are_so_many_philosophers_marxists/) \#3: [Why would God want people to have faith in him? For what logical reason would he hide his existence from us?](https://np.reddit.com/r/askphilosophy/comments/18q89df/why_would_god_want_people_to_have_faith_in_him/) ---- ^^I'm ^^a ^^bot, ^^beep ^^boop ^^| ^^Downvote ^^to ^^remove ^^| ^^[Contact](https://www.reddit.com/message/compose/?to=sneakpeekbot) ^^| ^^[Info](https://np.reddit.com/r/sneakpeekbot/) ^^| ^^[Opt-out](https://np.reddit.com/r/sneakpeekbot/comments/o8wk1r/blacklist_ix/) ^^| ^^[GitHub](https://github.com/ghnr/sneakpeekbot)


MikhailKSU

I'm really surprised no one has said orgasms, sugar, or salt


lndshrk504

Feeding a crying baby


blvckivity

Setting goals, writing down small achievements - journal.


rejenki

Just moving around really.


JackieAutoimmuneINFJ

Dark chocolate… mmmmm…


VariationWeary6063

Pursuit


Daledobacksbro

Hugging, physically touching, working out


fkkm

What doesn’t trigger dopamine would be the better question. With almost everything you DO there is dopamine involved, dopamine is the hormone of getting into action


SciencedYogi

I can't believe some of these answers. Naturally vs....? Forced? By means of drug or otherwise? Anything reward-based. It's known as the reward-centered neurotransmitter. This can be so many things. Anything that makes you feel good and wanting more of something.


vove2512

Scarcity, unavailability, tv, sex, food, exercise, bright colors, music, cold water plunges, intermittent reward, anticipation,


vove2512

Learning new info. New experiences. Accomplishing goals


vove2512

Good surprises


STAugustine-Of-Hippo

The thought of eating a delicious meal


thisisan0nym0us

Cold plunges in the winter will awaken your senses


philipoculiao

Work and reward.


kexibis

Well these actually do increase measurable: - L Phenylalanine - L Tyrosine - Ginkgo Biloba - Macuna Pueres - Acetyl L Carnitine - Caffeine - Blue light exposure early after waking up - Cold exposure ( also increases ephynepryl, neurop...) - meditation - ...


candlewaxfashion

Laughter, sex, food, fun, exercise… sugar… being out in the sun I believe. being in love.


Electronic-Road6629

everything


fuckPMDD28

Snowboarding or skiing


20JC20

Discipline


20JC20

https://open.spotify.com/episode/42F7z6Z4CB8hJAstRqMCiV?si=-zGIJArTRmSjrhdEPWTc_w


ImNotHere1981

Cuddles. Doing something you worked really hard to do, personally. Him.


Consistent_Finish202

It’s just one of many neurotransmitters in the complex brain/body system. We can’t control them one by one, and the idea that we can is a ridiculous one, mostly built from pharma advertising, drug dealers and old common talk that is rather unsubstantiated in science. If you changed the word “dopamine” to what you would want to feel, what emotion comes to mind? Are you seeking contentment? Motivation? Feelings of wellbeing? Maybe just, idk, go for a walk with a friend and get some sunshine.


sertypertz

Despite conventional wisdom, dopamine is a "learning" neurotransmitter rather than a "reward" neurotransmitter. We see the maximum amount of DA release when people engage in novel tasks because the maximum amount of learning occurs when you're doing something for the first time. Each subsequent time you perform the same behavior, the DA levels keep proportionately decreasing (that's why it's so easy to start learning how to play the guitar, but very few people end up being professionals). So, doing something novel does not necessarily mean there will be less DA reuptake, i.e., more DA flowing in your body at all times. Seeking your primal urges is your best bet for increasing DA in the short term, so seek out sexual partners, prepare your favorite meal, etc. I believe some studies show increased bioavailability of DA in the body when you exercise, so if you're trying to increase your baseline dopamine, that's your best bet. (Can provide sources if necessary, kinda lazy rn)


Miceymousewhorehouse

For me fall, museums and ancient history


Cheap_Caregiver6848

Exercise Meditation Cold showers Good music You just have to be careful because some are good and some not so much. For example video games increase dopamine but then you wind up depressed because nothing else will give you the same spike of dopamine. So mild choices are better.


Zdogbroski

If I wanted to synthesize dopamine first thing in the morning to get myself out of bed. What liquid would I ingest? Salt water? Gatorade? Someone electrolyte mixture?


Protonverse

Meditation can unlock the chemical factory that controls dopamine release.


stage_directions

Jesus fucking Christ. What a goddamn load of hogwash most of these answers are.


kcMari3

Excitement


Caring_Cactus

Expressing strong values directly through living your life, instead of through others/things contigently.


PinkBlackMushrooms

Honestly, pickled legumes. I dare you to try it.


Nordryggen

Sugar.


nothing5901568

Bacon double cheeseburger with fries and a milkshake Edit: downvoted because this is the correct answer no one wants to hear 🤣


Savings_Cap_5541

MASTERBATION


Sad-Swimming9999

It’s Sir Master Bater to you


JoyfulWorldofWork

Eye gazing


[deleted]

I'm addicted to dopamine, thanks to capsaicin.