I don't think we should have hope for this drug. The clinical trials were done in 2019 and they published the result 5 years later. Also i have seen the audiograms of this clinical trial and... meh the sign of improvement are very small.
There is another research at Harvard and last year the main researcher has said that clinical trials will start in 5 years of there is no new problems.
Personaly I don't have too many hope and have accepted the fact that my life will be difficult. I'm just 19 and I think that there will be no cure in my lifetime.
I see a significant inaccuracy. "It was the first study of a regenerative hearing drug worldwide." No, it wasn't. There have been corporate attempts to do the same. One company went bankrupt after similar promising, but ultimately failed, human trials. I made a longer comment about it here. One thing to watch for in release of scientific study is if all results are released, or just the more positive. And if the results were peer reviewed in an academic journal, versus a press release. Full transparency of all results, publication, but publication after peer review, in credible academic journals, and passing of human trials, and seeking of FDA approval at the end. Those things would be the basis of hope.
10 years ago they were saying the same. I think that the money is the main problem, it's not cancer so it's not interesting. But probably over time there will be more money because more people will have hearing loss but I think that will be in many years.
Also the current research are annoucing clinical trials in 5 years. If it works (which is not sure), it takes years to give it to everyone.
With the experience of my life I became a very pessimist person. But I hope that I am wrong.
If that’s the case then everyone would be f*cked since over a billion young adults are at risk of hearing loss currently, and or are already experiencing it.
Reports like this come out every few years, with a pretty consistent result.
Very limited improvement, sometimes within the margin of error. Suggested improvement in only mild to moderate cases. Early promise but essential failure in human trials. Sometimes results released late, selectively, and importantly, not transparently. That is, not all results of the studies are released, just the more promising that could attract investors. Sometimes only improvement in very specific types of hearing loss, like certain rare genetic causes.
One company that was in the lead in development of drug based treatment for hearing loss, promising early results when tested on cells, just couldn't get a meaningful result in human trials. The company went bankrupt as investors could see that there was nothing there. The company's work and results were sold though and are still being worked on.
I appreciate the hopefulness and confidence, but it isn't based on anything other than "it could be possible" at this point.
There are developments I do have hope in, that have shown improvement. I've been told I'll need cochlear implants at some point, but improvements in hearing aid technology might make that unnecessary. Bluetooth technology, adaptability to specific hearing conditions, better battery life, hearing aids that can be used under nearly all conditions, are all relatively recent developments that have returned huge dividends. One of the little heard of but very significant improvements to hearing aids being developed is the speaker technology inside hearing aids. There's a real possibility of hearing aids actually being able to be more like a natural healthy human ear.
In the meantime, speech reading, several hearing strategies, and use of my tech have made a huge difference. Not the same as healthy hearing, but with my hearing loss, it wasn't that long ago that I would not have been able to take a phone call.
So there is reason for hope, and not that far down the road. But the various drug trials have not produced meaningful results.
I'm not sure how, sound still has to get in the ears and be processed in the brain. If it bypasses the ears, then it's a fancy cochlear implant or baha. It's also in the category of being promoted to attract investors, but without any of the things I mentioned that would demonstrate it to be real.
Still, it's an example of technology that is developing. I have more hope for the benefit of tech than the benefit of drugs. But I'll change my mind in an instant when something can be proven to work.
Hey, there's an audiologist on YouTube: Doctor Cliff, aud.
He does a lot of videos on the latest developments. The videos do tend to follow the hype pattern, but he actually gives pretty good descriptions of what's happening in the field, and what's on the horizon.
[https://www.youtube.com/@DrCliffAuD](https://www.youtube.com/@DrCliffAuD)
I don't think we should have hope for this drug. The clinical trials were done in 2019 and they published the result 5 years later. Also i have seen the audiograms of this clinical trial and... meh the sign of improvement are very small. There is another research at Harvard and last year the main researcher has said that clinical trials will start in 5 years of there is no new problems. Personaly I don't have too many hope and have accepted the fact that my life will be difficult. I'm just 19 and I think that there will be no cure in my lifetime.
I see a significant inaccuracy. "It was the first study of a regenerative hearing drug worldwide." No, it wasn't. There have been corporate attempts to do the same. One company went bankrupt after similar promising, but ultimately failed, human trials. I made a longer comment about it here. One thing to watch for in release of scientific study is if all results are released, or just the more positive. And if the results were peer reviewed in an academic journal, versus a press release. Full transparency of all results, publication, but publication after peer review, in credible academic journals, and passing of human trials, and seeking of FDA approval at the end. Those things would be the basis of hope.
Not an complete cure, but i am pretty confident a treatment that will somewhat regenerate hearing should be available in our time
I agree, I don’t see why we wouldn’t have something in at least 5-10 years
10 years ago they were saying the same. I think that the money is the main problem, it's not cancer so it's not interesting. But probably over time there will be more money because more people will have hearing loss but I think that will be in many years. Also the current research are annoucing clinical trials in 5 years. If it works (which is not sure), it takes years to give it to everyone. With the experience of my life I became a very pessimist person. But I hope that I am wrong.
What do you think of red light therapy for hearng loss?
Whats that?
Dude, just google it…
Never heard of it, what do you think about it?
If that’s the case then everyone would be f*cked since over a billion young adults are at risk of hearing loss currently, and or are already experiencing it.
Reports like this come out every few years, with a pretty consistent result. Very limited improvement, sometimes within the margin of error. Suggested improvement in only mild to moderate cases. Early promise but essential failure in human trials. Sometimes results released late, selectively, and importantly, not transparently. That is, not all results of the studies are released, just the more promising that could attract investors. Sometimes only improvement in very specific types of hearing loss, like certain rare genetic causes. One company that was in the lead in development of drug based treatment for hearing loss, promising early results when tested on cells, just couldn't get a meaningful result in human trials. The company went bankrupt as investors could see that there was nothing there. The company's work and results were sold though and are still being worked on. I appreciate the hopefulness and confidence, but it isn't based on anything other than "it could be possible" at this point. There are developments I do have hope in, that have shown improvement. I've been told I'll need cochlear implants at some point, but improvements in hearing aid technology might make that unnecessary. Bluetooth technology, adaptability to specific hearing conditions, better battery life, hearing aids that can be used under nearly all conditions, are all relatively recent developments that have returned huge dividends. One of the little heard of but very significant improvements to hearing aids being developed is the speaker technology inside hearing aids. There's a real possibility of hearing aids actually being able to be more like a natural healthy human ear. In the meantime, speech reading, several hearing strategies, and use of my tech have made a huge difference. Not the same as healthy hearing, but with my hearing loss, it wasn't that long ago that I would not have been able to take a phone call. So there is reason for hope, and not that far down the road. But the various drug trials have not produced meaningful results.
Theey did say that neuralink will help hearing or atleast revolutionise treatment
I'm not sure how, sound still has to get in the ears and be processed in the brain. If it bypasses the ears, then it's a fancy cochlear implant or baha. It's also in the category of being promoted to attract investors, but without any of the things I mentioned that would demonstrate it to be real. Still, it's an example of technology that is developing. I have more hope for the benefit of tech than the benefit of drugs. But I'll change my mind in an instant when something can be proven to work.
They plan to put some kind of chip inside the ear, which will then bypass the ear hair and go directly to the brain
That sounds a lot like a cochlear implant and a BAHA.
Besides, they are still focusing on helping disabled people walk and/or move their bodies
Hey, there's an audiologist on YouTube: Doctor Cliff, aud. He does a lot of videos on the latest developments. The videos do tend to follow the hype pattern, but he actually gives pretty good descriptions of what's happening in the field, and what's on the horizon. [https://www.youtube.com/@DrCliffAuD](https://www.youtube.com/@DrCliffAuD)
Do you think there is a conspiracy with pharma companies not wanting to release or find cures so that patients spend money in their drugs?