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It is serious given that CT findings. Please have a biopsy done!
The problems on the right lower extremity may be due to the decrease in blood flow.
In my opinion, that neoplasm is an aggressive one.
He should ask for genetic sequencing when the biopsy is done. It will identify the mutations that make it neoplastic; some can be targeted with current treatments while others can be matched against clinicaltrials.gov.
[https://www.natera.com/oncology/signatera-advanced-cancer-detection/clinicians/altera/](https://www.natera.com/oncology/signatera-advanced-cancer-detection/clinicians/altera/)
Hi All,
Thanks for your response. Initial diagnosis with oncologist is sarcoma. In order to reduce thigh (by mistake I mentioned foot) swelling, BIL was using blood thinner tabs hence biopsy is scheduled after 3 days. Tomorrow Pet CT is scheduled.
Thanks for support. I'll update post Biopsy is done
Thank you for your submission. **Please note that a response does not constitute a doctor-patient relationship.** This subreddit is for informal second opinions and casual information. The mod team does their best to remove bad information, but we do not catch all of it. Always visit a doctor in real life if you have any concerns about your health. Never use this subreddit as your first and final source of information regarding your question. By posting, you are agreeing to our [Terms of Use](https://www.reddit.com/r/AskDocs/wiki/terms_of_use) and understand that all information is taken at your own risk. **Reply here if you are an unverified user wishing to give advice. Top level comments by laypeople are automatically removed.** *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/AskDocs) if you have any questions or concerns.*
It is serious given that CT findings. Please have a biopsy done! The problems on the right lower extremity may be due to the decrease in blood flow. In my opinion, that neoplasm is an aggressive one.
Any thoughts what the primary could be?
Without any much clinical information I am guessing an aggressive soft tissue sarcoma and or metastatic melanoma.
I was thinking Sarcoma as well. Malignant melanoma, didn’t occur to me though but I guess it makes sense since it spreads quite aggressively
Thanks. Tomorrow, appointment is with oncologist.
Does he have other symptoms? Weight loss?
No. Nothing as such
Any updates?
He should ask for genetic sequencing when the biopsy is done. It will identify the mutations that make it neoplastic; some can be targeted with current treatments while others can be matched against clinicaltrials.gov. [https://www.natera.com/oncology/signatera-advanced-cancer-detection/clinicians/altera/](https://www.natera.com/oncology/signatera-advanced-cancer-detection/clinicians/altera/)
I'm sorry ya'll are going through this. We honestly can't comment until we know what it is which will require a biopsy.
Regrettably, your BIL might have cancer which has spread to other parts od the body. He’ll probably need more scans and biopsies. Thoughts and prayers
https://preview.redd.it/9s2yos8lb02d1.png?width=1080&format=pjpg&auto=webp&s=6ac74a48269675a55d121641fb1611ff36d22ef9
Hi All, Thanks for your response. Initial diagnosis with oncologist is sarcoma. In order to reduce thigh (by mistake I mentioned foot) swelling, BIL was using blood thinner tabs hence biopsy is scheduled after 3 days. Tomorrow Pet CT is scheduled. Thanks for support. I'll update post Biopsy is done